Clinical trials: - Aortic Aneurysm
Iliac Aneurysm, Aortic Aneurysm, Abdominal
iHub Stent-Graft for Iliac Artery Aneurysms: Safety, Performance, and Effectiveness Study
The goal of this clinical trial is to evaluate the safety, performance, and Preliminary effectiveness of the iHub endoprosthesis system in treating iliac artery aneurysms in adult patients requiring endovascular repair.
- Trial name
- TriHub (NCT07005141)
- Testing
- Endovascular Iliac Branch Stent-Graft Implantation
- Where
- 2 sites in Brazil
- Volunteers
- 10 people
- Sponsor
- Archo Medical S.A
Abdominal Aortic Aneurism, Surgery
Study of the Glycocalyx in Abdominal Aortic Aneurysm
The investigators want to measure the degradation of the endothelial glycocalyx before and after clamping the aorta, in patients operated for a abdominal aortic aneurism.
- Conditions
- Abdominal Aortic Aneurism, Surgery, Ischemic Reperfusion Injury
- Trial name
- Endo_eAAA (NCT01834092)
- Testing
- Plasma
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vascular Diseases, Cerebrovascular Diseases
Evaluation of the Accuracy of the Vessel Navigator Tool for Catheterization of Supra-aortic Vessels - ARCHIBALD
This study compares the accuracy of fusion imaging (Fusion Roadmap) versus real-time X-ray imaging (Roadmap) during catheterization of supra-aortic trunks of in patients with aneurysms or arteriovenous malformations.
- Conditions
- Vascular Diseases, Cerebrovascular Diseases, Cardiovascular Diseases, Aortic Aneurysm
- Trial name
- ARCHIBALD (NCT03269734)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Vascular Graft Infection, Infectious Aortitis
China Aortic Infection and Graft Infection Study: An Ambispective Cohort
Vascular infections are uncommon but severe infections involving the arterial wall, vascular grafts, or endografts, and their diagnosis and management remain challenging.
- Conditions
- Vascular Graft Infection, Infectious Aortitis, Aortoenteric Fistula
- Trial name
- CAIGIS (NCT07847346)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Aortic Aneurysm, Aortic Aneurysm and Dissection
A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta
The Goal of this Clinical Study is to evaluate the safety and effectiveness of the Rapidlink device in the repair or replacement of the supra-aortic vessels during open surgical repair of aortic disease affecting the thoracic…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm and Dissection, Aortic Diseases, Aneurysm of Aorta, Thoracic
- Trial name
- RAPID (NCT07078383)
- Testing
- Rapidlink
- Where
- 21 sites in United States, Austria and 3 more
- Volunteers
- 150 people
- Sponsor
- Vascutek Ltd.
Endoleak, Abdominal Aortic Aneurysm
Contrast Enhanced Ultrasound, Endoleak Detection Following EVAR v1.3
A single site cross-sectional comparison of paired diagnostic imaging modalities. This study will show the sensitivity and specificity of CEUS in detecting the various types of endoleaks, in comparison to tCTA, following EVAR.
- Trial name
- NCT02688751
- Testing
- time-resolved CT Angiography, Contrast Enhanced Ultrasound
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Abdominal Aortic Aneurysm, Cardiovascular Events
Tonometry and Duplex Ultrasound to Predict AAA Progression and CV Events in Aneurysm Patients (1-2-3 Trial)
Abdominal aortic aneurysm (AAA) is a common vascular disease and associated with risk of rupture, but also with a high cardiovascular (CV) event rate.
- Trial name
- NCT03989011
- Testing
- Carotid Artery Reactivity test (CAR test), Arterial stiffness
- Where
- 3 sites in Netherlands
- Volunteers
- 167 people
- Sponsor
- Rijnstate Hospital
Aortic Dissection, Systemic Inflammatory Response Syndrome
Protective Effect of Sivelestat Against Negative Pulmonary Function and Organ Dysfunction After Cardiovascular Surgery (PANDA VI)
Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with cardiovascular diseases.
- Conditions
- Aortic Dissection, Systemic Inflammatory Response Syndrome, Cardiovascular Diseases (CVD)
- Trial name
- PANDA (NCT06195267)
- Testing
- Sivelestat, Blank control
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Abdominal Aortic Aneurysm, AAA
First In Human Study for Small to Medium-sized Abdominal Aortic Aneurysm (AAA)
This is a first in human study to evaluate the safety and clinical utility of an investigational medical device called the Nectero EAST System to treat Abdominal Aortic Aneurysms or AAA.
- Conditions
- Abdominal Aortic Aneurysm, AAA, Dilation Aorta
- Trial name
- AAA (NCT05133492)
- Testing
- Endovascular Aneurysm Stabilization Treatment (EAST)
- Where
- 5 sites in Australia, China and 3 more
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nectero Medical, Inc.
EHLERS-DANLOS SYNDROME, TYPE IV, AUTOSOMAL DOMINANT, CHROMOSOME 2q31.2 DELETION SYNDROME
Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular Type
Ehlers-Danlos syndrome vascular type (EDS-IV) is caused by a genetic defect of collagen type III. Patient die (median 40 yrs) of vascular complications. There is no treatment.
- Trial name
- NCT00190411
- Testing
- celiprolol, Control
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Aortic Aneurysm
Transthoracic Ultrasound Evaluation of Thoracic Aortic Aneurysms
The Diagnosis of a thoracic Aortic Aneruysms usually made when imaging an abdominal aortic aneurysm which has reached threshold or as an incidental finding during a chest scan by computed tomography (CT) or magnetic resonance…
- Trial name
- NCT05137366
- Testing
- Transthoracic ultrasound scan
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Aortic Dissection
The Relationship Between ALDH2 and Aortic Dissection
The purpose of this study is to evaluate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection.
- Trial name
- RALAD (NCT02630212)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Qilu Hospital of Shandong University
Vascular Ehlers-Danlos Syndrome
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients
Vascular Ehlers-Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein.
- Trial name
- NCT05994664
- Testing
- Heartmath Intervention, Control Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Aortic Aneurysm, Abdominal
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
The aim of this randomized study is to compare the safety and performance of EndoVascular Aneurysm Repair with ESAR using Endurant + Heli-FX™ EndoAnchor™ system and FEVAR using customizable grafts from Cook (Zenith Fenestrated…
- Trial name
- SOCRATES (NCT04503395)
- Testing
- ESAR treatment: Endograft + Heli-FX Endoanchor, FEVAR treatment : Fenestrated endograft
- Where
- 33 sites in United States, Austria and 8 more
- Volunteers
- 204 people
- Sponsor
- FCRE (Foundation for Cardiovascular Research and Education)
Aortic Valve Disease
Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)
The ASCEND post-market clinical follow-up study is undertaken to evaluate safety and clinical performance of the On-X Ascending Aortic Prosthesis (AAP) used in surgical aortic valve replacement.
- Trial name
- ASCEND (NCT05082454)
- Testing
- Open repair
- Where
- 11 sites in United States, Germany and 3 more
- Volunteers
- 108 people
- Sponsor
- JOTEC GmbH
Abdominal Compartment Syndrome
Abdominal Compartment Syndrome and Ruptured Aortic Aneurysm : Validation of a Predictive Test
It is an observational study on ruptured abdominal aortic aneurysm and abdominal compartment syndrome. the aim of this study is to assess the qualities of a predictive score on the occurence of this syndrome after surgery of…
- Trial name
- SCA-AAR (NCT02859662)
- Testing
- ruptured aortic aneurysm
- Where
- 10 sites in France
- Volunteers
- 165 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Aortic Aneurysm, Aortic Dissection
Characterization of Aortic Tissue at Reoperation
This study will analyse factors contributing to cardiac re-operation to determine causative effects
- Trial name
- NCT02375542
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- CryoLife Europa
Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Surgery and Thrombosis
The aim of our study is to evaluate the incidence of post-operative thrombotic complications after abdominal aortic aneurysm surgery in the context of atherosclerosis or infectious aneurysm and its links with preoperative…
- Trial name
- AAA-IT (NCT04325373)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease, Arteriosclerosis
Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension.
- Conditions
- Coronary Artery Disease, Arteriosclerosis, Carotid Stenosis, Thrombosis
- Trial name
- NCT01106573
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
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