Clinical trials: 18F-FAPI, open to volunteers
Thyroid Eye Disease
Exploring the Value of 18F-AlF-FAPI PET/CT in Assessing the Activity of Thyroid Eye Disease
FAPI PET has been developed as a promising approach for the evaluation of fibroinflammatory, such as in inflammatory bowel disease.
- Trial name
- NCT06359795
- Testing
- 18F-AlF-FAPI PET/CT, 99mTc-DTPA SPECT/CT
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Advanced Colorectal Cancer
The Role of 18F-FDG and 68Ga-FAPI PET/CT in the Diagnosis and the Efficacy Evaluation of Advanced Colorectal Cancer (peritoneal Metastasis With/without Other Metastases)
This study aims to investigate the value of 18F-FDG and 68Ga-FAPI PET/CT in evaluating the outcome of conversion therapy and the prognosis of advanced colorectal cancer (peritoneal metastasis with/without other metastases)
- Trial name
- NCT06601075
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital
Cholangiocarcinoma
The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal Cholangiocarcinoma
Background Bile duct cancer (cholangiocarcinoma) represents the second most common type of hepatobiliary cancer worldwide with an incidence of 0.35 to 2 per 100.000 annually.
- Trial name
- FAPIChol (NCT06355427)
- Testing
- [18F]F-FAPI PET-CT
- Where
- 3 sites in Netherlands
- Volunteers
- 81 people
- Sponsor
- Mara Veenstra, MD
Breast Neoplasm Female
Piloting 18F-FAPI PET/MRI for Applications in Breast Cancer
Breast cancer is the most common type of cancer in Norwegian women, with 4,224 new cases in 2022. More precise diagnosis are expected to result in more accurate assessment of treatment effect, and to contribute to both providing…
- Trial name
- NCT07180433
- Testing
- FAPI PET/MR
- Volunteers
- 60 people
- Sponsor
- St. Olavs Hospital
Allogeneic Stem Cell Transplantation, Lung Allograft Transplantation
Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging
Background: Injury or diseases of the heart and lung can sometimes cause scar tissue (fibrosis) to build up in those organs. Current imaging scans can see this scar tissue once it has formed, but researchers want to find a way to…
- Conditions
- Allogeneic Stem Cell Transplantation, Lung Allograft Transplantation, Interstitial Lung Disease, Acute Lung Injury
- Trial name
- NCT07613099
- Testing
- [18F]FAPI-74, 18F-FAPI-74 PET/CT Imaging
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myelofibrosis
18F-FAPI PET/MRI Imaging in Myelofibrosis: a Prospective Observational Study.
This study intends to use a prospective, observational, self-controlled, multi-center study design to evaluate the feasibility and diagnostic efficacy of 18F-FDG PET/CT and 18F-FAPI PET/MRI imaging for the evaluation of systemic…
- Trial name
- NCT06164561
- Where
- China
- Volunteers
- 57 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Pancreatic Ductal Adenocarcinoma (PDAC)
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)
This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of [¹⁸F]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically confirmed pancreatic ductal…
- Trial name
- FAPI-PRO (NCT07217717)
- Testing
- [18F]FAPI-74 PET/CT
- Where
- 19 sites in United States
- Volunteers
- 200 people
- Sponsor
- SOFIE
Cancer of Unknown Primary
[18F]F-FAPI PET-CT to Identify Carcinoma of Unknown Primary Origin
The investigators will determine the proportion of CUP patients in whom the primary tumor can be identified by [18F]F-FAPI PET-CT.
- Trial name
- FAPI for CUP (NCT06644716)
- Testing
- [18F]F-FAPI PET-CT
- Where
- 6 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasmus Medical Center
Acute Myocardial Infarction, Ventricular Aneurysm Following Acute Myocardial Infarction
Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm
The study will use 18F-FAPI PET/CT to study myocardial fibrosis in patients diagnosed with myocardial infarction-associated ventricular aneurysm (MI-VA).
- Conditions
- Acute Myocardial Infarction, Ventricular Aneurysm Following Acute Myocardial Infarction, Myocardial Fibrosis
- Trial name
- NCT06994221
- Testing
- 18F FAPI-42 PET/CT scan
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Chronic Kidney Disease, Cardiac Magnetic Resonance
Multimodal Imaging Assessment of Chronic Kidney Disease Patients at Different Stages From a Cardio-Renal Interaction Perspective
This study is a prospective cohort investigation in which consecutive eligible patients undergo 18F-FAPI PET/MR imaging. Chronic kidney disease (CKD) participants are stratified into two groups:Group I ：CKD stages 1-3（eGFR ≥ 30…
- Conditions
- Chronic Kidney Disease, Cardiac Magnetic Resonance, 18F-FAPI
- Trial name
- NCT07107919
- Testing
- 18F PET/MR
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastric Cancer
18F-FAPI PET/CT and MRI in Gastric Cancer
The purpose of this study was to evaluate the diagnostic efficacy and prognostic value of 18F-FAPI PET/CT combined with multiparameter MRI in gastric cancer.
- Trial name
- NCT07510867
- Testing
- patients with suspected or confirmed gastric cancer who have undergone 18F-FAPI PET/CT and MRI (non-contrast + contrast-enhanced scans)
- Where
- China
- Volunteers
- 230 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
AL Amyloidosis (AL), Cardiac Amyloidosis
Multimodal Radiomics Model (18F-FAPI PET/CT + CMR) for AL Cardiac Amyloidosis Prognosis
1. Goal of the Study: The goal of this prospective observational study is to develop and validate a novel, non-invasive method for predicting the prognosis of patients with light-chain cardiac amyloidosis (AL-CA).
- Trial name
- AL-CA (NCT07103863)
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Beijing Anzhen Hospital