Clinical trials: 2019-nCoV
Coronavirus Infections
French COVID Cohort
Infectious disease is the single biggest cause of death worldwide. New infectious agents, such as the SARS, MERS and other novel coronavirus, novel influenza viruses, viruses causing viral haemorrhagic fever (e.g.
- Trial name
- FrenchCOVID (NCT04262921)
- Where
- 98 sites in France
- Volunteers
- 4,415 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
2019-nCoV Severe Pneumonia
The Efficacy of Different Hormone Doses in 2019-nCoV Severe Pneumonia
At present, there is no specific and effective antiviral therapy.In this study, an open, prospective/retrospective, randomized controlled cohort study was designed to compare the efficacy of different hormone doses in the…
- Trial name
- NCT04263402
- Testing
- Methylprednisolone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Covid19, Pneumonia
Coronavirus: Ventilator Outcomes Using Artificial Intelligence Chest Radiographs & Other Evidence-based Co-variates
We will determine ventilator outcomes to Coronavirus Infectious Disease 2019 (COVID-19) using artificial Intelligence with inputs of chest radiographs and other evidence-based co-variates.
- Trial name
- COVID VOICE (NCT04855539)
- Where
- 3 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- King's College Hospital NHS Trust
Colorectal Carcinoma, COVID 19
Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer
The goal of this observational study is to assess the impact of the COVID-19 pandemic on colorectal cancer (CRC) outcomes, particularly focusing on stage distribution and recurrence-free survival in patients undergoing surgery at…
- Trial name
- NCT06638957
- Where
- South Korea
- Volunteers
- 14,951 people
- Sponsor
- In Ja Park
Infection of Upper Respiratory Tract Caused by 2019-nCoV
SA55 Injection Phase II Study in the Treatment of Mild/Moderate COVID-19 Patients
Evaluating the efficacy and safety of SA55 injection in light/medium COVID-19 patients
- Trial name
- NCT06042764
- Testing
- SA55 Injection
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Coronavirus Infection, Disease Prevention
Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment
The purpose of this study is to assess the safety and efficiency of an assembled modified mask in protecting health care workers against Coronavirus in case of any personal protective equipment shortage.
- Trial name
- NCT04416919
- Testing
- Assembled mask
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
COVID-19 Pneumonia, Thrombosis
Practice Variation on Antithrombotics in COVID-19
Evidence suggests coronavirus disease 2019 (COVID-19) is associated with an increased incidence of thromboembolic manifestations.
- Conditions
- COVID-19 Pneumonia, Thrombosis, COVID-19 Acute Respiratory Distress Syndrome, Severe Acute Respiratory Syndrome (SARS) Pneumonia
- Trial name
- NCT04998799
- Testing
- Current clinical practices of participating physicians
- Where
- India
- Volunteers
- 435 people
- Sponsor
- NMC Specialty Hospital
2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection
LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)
This master protocol serves as a common reference for the inpatient and outpatient clinical studies that share common elements.
- Conditions
- 2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection, 2019-nCoV Disease, 2019-nCoV Infection
- Trial name
- NCT05077332
- Testing
- Famotidine, Celecoxib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Leidos Life Sciences
Acute Myeloblastic Leukemia, Acute Lymphoblastic Leukemia
Multicentric Registry of Patients With Acute Leukemia Infected by COVID-19
The COVID-19 epidemic (Coronavirus Disease 2019) currently raging in France is an emerging infectious disease linked to a virus of the genus coronavirus (SARS-CoV-2).
- Conditions
- Acute Myeloblastic Leukemia, Acute Lymphoblastic Leukemia, SARS-CoV-2
- Trial name
- COVLA (NCT04452604)
- Where
- 27 sites in France
- Volunteers
- 79 people
- Sponsor
- French Innovative Leukemia Organisation
Sarcoidosis, COVID-19
Number of Participants Diagnosed With Sarcoidosis by Bronchoscopic Transbronchial Needle Aspiration After COVID- 2019 .
The goal of this observational study is to learn about sarcoidosis development after COVID-19 infection. The main question it aims to answer is: prevalence of Sarcoidosis among patients previously infected with COVID-19.
- Trial name
- NCT06043882
- Testing
- flexible bronchoscopy
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Ain Shams University
SARS-CoV2
CANnabiDiol for CoviD-19 pATiEnts With Mild to Moderate Symptoms
The aim of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabidiol (CBD - 300 mg a day) in patients infected with SARS-CoV-2.
- Trial name
- CANDIDATE (NCT04467918)
- Testing
- Cannabidiol
- Where
- 2 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
COVID-19, Pneumonia
A Study of LY3127804 in Participants With COVID-19
A randomized, double-blind, placebo-controlled, clinical trial of LY3127804 in participants who are hospitalized with pneumonia and presumed or confirmed COVID-19.
- Trial name
- NCT04342897
- Testing
- LY3127804
- Where
- 13 sites in United States
- Volunteers
- 95 people
- Sponsor
- Eli Lilly and Company
Coronavirus
Viral Excretion in Contact Subjects at High/Moderate Risk of Coronavirus 2019-nCoV Infection. COVID-19.
In December 2019, a pneumonia due to a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, in China. In a few weeks, the number of confirmed cases of SARS-CoV-2 infection has dramatically increased, with almost 150'000…
- Trial name
- Cov-CONTACT (NCT04259892)
- Testing
- 2019-nCoV PCR
- Where
- 16 sites in France, French Guiana
- Volunteers
- 324 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Critical Illness, Infections, Respiratory
Using Telemedicine to Optimize Teamwork and Infection Control of Critical and Highly-infectious Patients in an Emergency Department
Since 2000, various emerging infectious diseases have repeatedly caused serious impact on the health of the global population and the healthcare systems.
- Conditions
- Critical Illness, Infections, Respiratory, Emergency Service, Hospital, Telemedicine
- Trial name
- NCT04591873
- Testing
- telemedicine, traditional communication tools
- Where
- Taiwan
- Volunteers
- 74 people
- Sponsor
- National Taiwan University Hospital
Pneumonia Caused by Human Coronavirus
Clinical Progressive Characteristics and Treatment Effects of 2019-novel Coronavirus
Objects: The purpose of this study was to observe the characteristics of morbidity, disease progression and therapeutic effects of 2019-novel coronavirus pneumonia patients with different clinical types.
- Trial name
- 2019-nCoV (NCT04292327)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Fujian Provincial Hospital
SARS-CoV-2 Infection, COVID-19
Safety and Effects of an Investigational COVID-19 Vaccine as Booster in Healthy People
This was an exploratory Phase I, randomized, observer-blind, active-controlled, dose-escalation trial to evaluate four dose levels (DLs) of BNT162b4 given in combination with BNT162b2 Bivalent (original/Omicron BA.4/BA.5) to…
- Trial name
- NCT05541861
- Testing
- BNT162b2 Bivalent (original/Omicron BA.4/BA.5) 30 mcg, BNT162b4 5 mcg, BNT162b4 10 mcg
- Where
- 17 sites in United States
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Covid19
Microbial Infection and AMR in Hospitalized Patients With Covid 19
To detect microbial infection and AMR associated with COVID 19 infection. To correlate risk factors of COVID 19 patients with microbial infections and their effects on disease.
- Trial name
- NCT04479982
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
COVID-19; SARS-CoV-2; 2019 Novel Coronavirus Disease
eVusheld Assessment reaL wORld Effectiveness in DoD Health System
An AstraZeneca-sponsored observational, electronic healthcare record (EHR)-embedded retrospective cohort study to assess the real-world effectiveness of EVUSHELD against SARS-CoV-2 infection, COVID-19-related hospitalization, and…
- Trial name
- VALOR DoD (NCT05569408)
- Testing
- EVUSHELD
- Where
- United States
- Volunteers
- 4,724 people
- Sponsor
- AstraZeneca
Covid19
Prevention With Chloroquine in Health Personnel Exposed to Infection With Coronavirus Disease 2019 (COVID-19) (TS-COVID)
The purpose of this study is to assess the efficacy and safety of chloroquine prophylaxis on the incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections in healthcare workers exposed to patients with…
- Trial name
- TS-COVID (NCT04627467)
- Testing
- Chloroquine
- Where
- Colombia
- Volunteers
- 3,217 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili
COVID-19
Prazosin to Prevent COVID-19 (PREVENT-COVID Trial)
The purpose of this study is to assess the efficacy and safety of prazosin to prevent cytokine storm syndrome and severe complications in hospitalized patients with Coronavirus disease 2019 (COVID-19).
- Trial name
- PREVENT (NCT04365257)
- Testing
- Prazosin, Standard of care
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University