Clinical trials: A
Cervical Cancer, Precancerous Condition
Combined Digital Colposcopy Analysis to Improve Cervical Precancer and Cancer Detection
Precancerous lesions of the cervix occur frequently and are treatable. This justifies a population-based screening program. Following an abnormal Pap smear, patients are referred for a colposcopic exam to confirm the…
- Trial name
- MDC_Algo (NCT01094132)
- Testing
- Multispectral Digital Colposcope (MDC)
- Where
- 3 sites in United States, Canada
- Volunteers
- 551 people
- Sponsor
- British Columbia Cancer Agency
Depression, Anxiety
Depression and Anxiety in the Aetiology and Prognosis of Specific Cardiovascular Disease Syndromes: a CALIBER Study
People report feeling sad and low (depression) or worried (anxiety) appear more likely to subsequently suffer a heart attack, or angina. However it is not known whether depression or anxiety actually causes heart disease.
- Conditions
- Depression, Anxiety, Coronary Disease, Cardiovascular Disease
- Trial name
- NCT01240798
- Where
- United Kingdom
- Sponsor
- University College, London
Gingivitis, Plaque, Dental
Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems as Compared to a Control Mouthwash
Qualified subjects will be enrolled and randomized to either one of the two study groups described above based on their initial modified gingivitis and plaque scores.
- Trial name
- NCT07263698
- Testing
- cetylpyridinium chloride (CPC), zinc lactate and sodium fluoride Mouthwash, sodium fluoride Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Neovascular
Panretinal Photocoagulation for Proliferative Diabetic Retinopathy in a Single Session Using Low Fluence Parameters
Is it possible to do a panretinal photocoagulation for proliferative diabetic retinopathy in a single session using low fluence parameters?
- Trial name
- PFC (NCT01023698)
- Testing
- laser photocoagulation
- Volunteers
- 30 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Executive Functions (EF), Decision Making
Effects of Cognitive Training on Executive Functions and Decision-Making in Adolescent Female Volleyball Players
This randomized controlled trial aims to evaluate the effects of a four-week tablet-based cognitive training program on executive functions and on-court decision-making performance in adolescent female volleyball players.
- Conditions
- Executive Functions (EF), Decision Making, Volleyball
- Trial name
- NCT07692698
- Testing
- Tablet-Based Cognitive Training, Routine Volleyball Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Firat University
Stroke
Pilot Study on Comparisons Between the Effectiveness of Mobile Video-guided and Paper-based Home Exercise Programs of Patients With Stroke Randomized Controlled Trial
This is a pilot study and a randomized, controlled, assessor-blinded clinical trial for patients who will complete the inpatient Stroke Rehabilitation Program in the Department of Medical and Geriatrics of Tai Po Hospital and…
- Trial name
- NCT03509363
- Testing
- Stroke physiotherapy home exercise video
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- Tai Po Hospital
PreDiabetes
Digital Diabetes Prevention Program Study
The aim of this study is to determine if completion of the Diabetes Prevention Program (DPP) via the Transform 10 website can significantly decrease hemoglobin A1c (HbA1c) levels and Body Mass Index (BMI) in prediabetic…
- Trial name
- NCT06137963
- Testing
- Transform10 Diabetes Prevention Program
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Ergonomics, Virtual Reality Headset
Feasibility and Ergonomic Impact of A Virtual Reality Headset in Endoscopic Procedures
The purpose of this study is to assess the feasibility of using a virtual reality headset (VRH) during endoscopy and its impact on the endoscopist ergonomics.
- Conditions
- Ergonomics, Virtual Reality Headset, Virtual Reality, Endoscopy
- Trial name
- NCT07493863
- Testing
- Virtual reality headset, MYSELF checklist
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Osteoporosis
Effect of Class IV Laser Therapy and Pilates Exercises on Bone Density and Pain in Primary Osteoporosis: A Randomized Controlled Trial
the current study was to investigate the effect of class IV laser therapy and Pilates exercises on bone density in Osteoporosis.Sixty patients with osteoporosis (T-score values below -2.5) in lumbar spine with no evidence of…
- Trial name
- NCT04646863
- Testing
- laser therapy, exercise, combination
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Iron Metabolic Homeostasis
Effect of Vitamin A Supplementation on Iron Metabolic Homeostasis of Preschool Children in Sichuan,China
The investigators plan to perform a randomized, mutual-control and double-blinded cohort study to further exploit the vitamin A supplementation on iron metabolic homeostasis (including iron reserve, mobilization and absorption…
- Trial name
- NCT01355263
- Testing
- iron and vitamin a
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Chengdu Maternal and Children's Health Care Hospital
Labor, Induced
'Extended Balloon Catheter' Labour Induction; a Single Arm Pilot Trial'
The overall aim of the single arm pilot study was to assess the effectiveness, safety and acceptance of the 'extended balloon catheter' as a method of induction of labour in women receiving care at Princess Marina Hospital(PMH)…
- Trial name
- NCT05885087
- Testing
- Foley or balloon catheter
- Where
- Botswana
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Botswana
Solid Tumor, Adult
Tolerability and Safety of HF1K16 Injection in Patients With Refractory Solid Tumors
HF1K16 is an investigational pegylated liposome formulation of All-Trans Retinoic Acid (ATRA) for the induction of remission in patients with acute promyelocytic leukemia (APL) and for the treatment of solid tumors through…
- Trial name
- NCT05388487
- Testing
- HF1K16 /Arm 45 mg/m², HF1K16 /Arm 90 mg/m², HF1K16 /Arm 120 mg/m²
- Where
- 7 sites in China
- Volunteers
- 54 people
- Sponsor
- HighField Biopharmaceuticals Corporation
Healthy
Safety and Efficacy of Lidocaine Infiltration in Suction Assisted Lipectomy
RCT of S/E of lidocaine infiltration in tumescent technique.
- Trial name
- NCT00591487
- Testing
- Lidocaine
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Militar de Santiago
Infection, Human Immunodeficiency Virus
A Drug Interaction Study Evaluating GSK2248761 and Raltegravir Pharmacokinetics in Healthy Adult Subjects
In this study, approximately 16 subjects will receive raltegravir 400mg twice daily for 5 days (Treatment A) followed by a washout period. In Period 2, subjects will receive GSK2248761 200mg once daily for 5 days (Treatment B).
- Trial name
- NCT01101893
- Testing
- Raltegravir, GSK2248761, GSK2248761 + Raltegravir
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Cocaine Use, Cocaine Intoxication
Comparing Efficacy & Safety Of TNX-1300 To Placebo With UC For Treatment Of Acute Cocaine Intoxication In ED Subjects (CATALYST)
This is a Phase 2 single-blind, randomized, multicenter study to compare the efficacy and safety of a single dose of TNX-1300 to placebo with usual care in patients with acute cocaine intoxication within the emergency department…
- Conditions
- Cocaine Use, Cocaine Intoxication, Cocaine Toxicity, Cocaine Abuse
- Trial name
- CATALYST (NCT06045793)
- Testing
- TNX-1300 (Injection)
- Where
- 6 sites in United States
- Volunteers
- 3 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Hamstring Injury, Masseter
Immediate Effects of Hamstring Stretching Alone or Combined With Myofascial Release
To assess the immediate effects of hamstring stretching alone or combined with myofascial release of the hamstring muscle on masseter muscle activity, pressure pain threshold, active mouth opening, hamstring flexibility, and…
- Conditions
- Hamstring Injury, Masseter, Myofascial Release, Stretching
- Trial name
- NCT05702593
- Testing
- Static stretching, Myofascial Release
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Chronic Migraine Headache, Psychologic Adaptation
Psychological Support for Chronic Migraine Patients Treated With Anti-CGRP (Anti-Calcitonin Gene-Related Peptide ) Monoclonal Antibodies
Chronic migraine is a disabling neurological condition that can significantly affect quality of life, emotional well-being, social participation, and daily functioning.
- Trial name
- MIG-PSY-CGRP (NCT07877493)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Rhinitis, Allergic, Perennial
A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis
The purpose of this study is to assess long-term ocular safety of fluticasone furoate nasal spray in adult and adolescent subjects diagnosed with perennial allergic rhinitis.
- Trial name
- NCT00682643
- Testing
- fluticasone furoate nasal spray
- Where
- 56 sites in United States
- Volunteers
- 550 people
- Sponsor
- GlaxoSmithKline
Solid Tumors
MSB0011359C (M7824) in Participants With Metastatic or Locally Advanced Solid Tumors
The main purpose of this study was to assess the safety and tolerability of MSB0011359C. Study consists of dose-escalation part and an expansion part in participants with metastatic or locally advanced solid tumors, for which no…
- Trial name
- NCT02699515
- Testing
- MSB0011359C
- Where
- 18 sites in Japan, South Korea and 1 more
- Volunteers
- 114 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Constriction, Pathologic
FLAIR™ Delivery System Study
The objective of this clinical study is to evaluate the performance of the Optimized FLAIR™ Delivery System.
- Trial name
- FLAIR DS (NCT00614315)
- Testing
- FLAIR™ Endovascular Stent Graft
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- C. R. Bard
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