Clinical trials: A
Acne Vulgaris
A Phase 2 Safety and Efficacy Study of UHE-101 Cream in Subjects With Acne Vulgaris
UHE-101 cream, 1% ("UHE-101") is being developed for the topical treatment of acne vulgaris. The purpose of this study is to compare the safety and efficacy of twice daily topical application of UHE-101 cream for 12 weeks to its…
- Trial name
- NCT03307577
- Testing
- UHE-101 Cream, Vehicle Cream
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Therapeutics, Inc.
HIV
Evaluate the Tolerability and Therapeutic Effects of Repeated Doses of Autologous T Cells With VRX496 in HIV
The study is intended for individuals who are doing well on HAART therapy. In Step 1 of the trial, individuals will be given up to 6 infusions of the study drug VRX496 to see the effect on viral load and CD4 counts.
- Trial name
- NCT00295477
- Testing
- VRX496
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pennsylvania
OCD
A Clinical Protocol for VR-Assisted CBT Targeting Quality of Life Outcomes for OCD
This study aims to evaluate the effectiveness of VR interventions in improving the psychological quality of life among OCD patients.
- Trial name
- NCT07857577
- Testing
- VR-CBT, G-VRET
- Where
- Malaysia
- Volunteers
- 36 people
- Sponsor
- National University of Malaysia
Injury Prevention in Sports, Sports Performance
Effectiveness of a Judo-specific Injury Prevention Programme on Performance in Judo Athletes
Judo is a popular international combat sport with an estimated 20 million active participants world-wide and participation in judo entails a substantial risk of injury in both elite and recreational judo.
- Conditions
- Injury Prevention in Sports, Sports Performance, Sports
- Trial name
- JUDO-RCT (NCT06929377)
- Testing
- IPPON warm-up programme
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Heart Rate Variability, Body Fat
The Impact of Re-training Following Detraining on Greco-Roman Wrestlers
The aim of this study is to analyse the alterations in the physical, physiological, and performance characteristics of the elite Greco-Roman wrestlers who experienced a prolonged period of detraining (14 weeks) as a result of the…
- Conditions
- Heart Rate Variability, Body Fat, Wrestling, Fitness Testing
- Trial name
- NCT06606977
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tuba Melekoğlu
Primary Breast Cancer
Neoadjuvant Doxorubicin/Cyclophosphamide Followed by Docetaxel (AC-Doc) Versus Dose-Dense Doxorubicin and Docetaxel (ADoc) in Breast Cancer
The primary objective of this trial is to compare the rate of pathologically complete remissions achieved using a preoperative dose-intensified 8 week therapy consisting of adriamycin and docetaxel with a preoperative sequential…
- Trial name
- NCT00793377
- Testing
- Adriamycin (Doxorubicin), Docetaxel, Tamoxifen, Adriamycin (Doxorubicin), Docetaxel, Tamoxifen, Cyclophosphamid
- Where
- Germany
- Volunteers
- 913 people
- Sponsor
- GBG Forschungs GmbH
Emotional Processing, Mental Exercise
Effects of a Brief Mental Exercise on Emotional Processing
The aim of this study is to explore whether a brief mental exercise (developed and widely advocated in the field of positive psychology) can change the processing of emotion-related information in a similar way as previously…
- Trial name
- BME (NCT03698175)
- Testing
- Three good things exercise
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Aging, Diagnostic Techniques, Cardiovascular
Evolution of the Relationship Between Central and Peripheral Arterial Wave Velocities as a Function of Age
Acquisition of synchronized cardiovascular signals from non-invasive measurements (ECG, photoplethysmography pulse sensors, inductance plethysmography) in healthy volunteers aged from 18 to 75, during spontaneous ventilation with…
- Trial name
- EvolVOAge (NCT06742775)
- Testing
- physiological signal acquisitions
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Traumatic Brain Injury
Traumatic Brain Injury and Effects of Acute Cyclosporine A
This is a prospective, randomized, placebo-controlled study about Cyclosporine A (CSP) and traumatic brain injury (TBI). Cyclosporine A is a drug already marketed and available for other diseases, but is not approved by the Food…
- Trial name
- NCT02496975
- Testing
- Cyclosporine A
- Where
- United States
- Sponsor
- Edward Hall,PhD
Spinal Diseases
Effect of PEEP on Intraoperative Hypothermia
Intraoperative hypothermia is associated with many clinical adverse outcomes. Many techniques were applied to prevent intraoperative hypothermia, and positive end-expiratory pressure (PEEP) has been known to blunt intraoperative…
- Trial name
- NCT02416557
- Testing
- PEEP
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Seoul National University Hospital
Osteoarthitis
Effects of Kinesiotaping in Osteoarthritis
Knee osteoarthritis will be recognized as a leading cause of pain and functional disability, and conventional physiotherapy will remain a cornerstone of its management.
- Trial name
- Taping (NCT07606157)
- Testing
- Kinesiotaping
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nazli Cigercioglu
Diabetes Mellitus: Type 1
A Study Designed to Compare 2 Dose Strengths of TI Inhalation Powder in Adults With Type 1 Diabetes Mellitus and to Compare One of Those Formulations (30Units) With an Injection of Insulin Lispro
28 subjects to be enrolled for a screening period, 3 dosing visits \& a follow-up visit. Visits 2 and 3 dosing of TI Inhalation Powder, cross over between two 15 U cartridges and one 30 U cartridge.
- Trial name
- NCT00662857
- Testing
- Technosphere® Insulin Inhalation Powder, Technosphere Insulin® Inhalation Powder, RAA Population
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Mannkind Corporation
Lung Neoplasms, Quality of Life
Impact on Quality of Life From Multi-modality Lung Cancer
The investigators aim to explore how lung cancer patients and their family carers are affected by different types of cancer treatment. The investigators are focusing on a particular type of lung cancer called Stage III N2.
- Trial name
- PIONEER (NCT04540757)
- Testing
- Surgery, No surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 66 people
- Sponsor
- The Christie NHS Foundation Trust
Pneumothorax, Biopsy Wound
Pneumothorax After CT-guided Lung Biopsy: Standard vs Autologous Blood Patching
The aim of this prospective, randomized study is to compare the rate of postoperative pneumothorax between standard CT-guided core needle biopsy (CNB) versus CNB followed by autologous blood patch injection (ABPI).
- Trial name
- BloodyBiopsy (NCT03804957)
- Testing
- Autologous blood patch injection (ABPI), CT-guided core needle biopsy (CNB)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Humanitas Clinical and Research Center
COPD Exacerbation
A Cross Sectional, Diagnostic Accuracy Study to Validate the Use of a New Device(Inflammacheck™) in Diagnosing COPD
A cross-sectional, diagnostic accuracy study to evaluate the use of the 'Inflammacheck™' device in the diagnosis of COPD. Participants will be asked to provide an exhaled breath sample for measurement of their EBC H2O2 using…
- Trial name
- EXHALE 1V (NCT04024657)
- Where
- United Kingdom
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Diabetes, Senile Dementia, Alzheimer Type
A Study of Mobile Medical Supportive Care Program for Family Caregivers With Dementia Combined With Diabetes
The purpose of this project is to evaluate the effectiveness of the clinical application of a mHealth supportive care program for family caregivers with dementia combined with diabetes based on the supportive care framework.
- Trial name
- NCT06785857
- Testing
- mHealth Supportive Care Program, Offline supportive care
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuanjiao Yan
COVID-19
Epidemiology of IgA Selective Deficiency - Clinical Manifestations and Risk of Transmission
The management of patients with a selective IgA deficiency currently consists of symptomatic treatment with treatment of infections by occasional or prolonged antibiotic therapy, immunosuppressive treatments for autoimmune…
- Trial name
- EpIgA (NCT06125457)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Antimicrobial Resistance
Algorithm Using a Rapid Diagnostic Test for the Management of Childhood Febrile Diseases.
In Sub-Saharan Africa (SSA), fever remains a major public health problem in children. The introduction of malaria rapid diagnostic tests (RDTs) in routine healthcare has greatly improved the management of malaria.
- Trial name
- e-MANIC (NCT05285657)
- Testing
- Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)
- Where
- 2 sites in Burkina Faso
- Volunteers
- 1,176 people
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso
Schizophrenia, Schizoaffective Disorder
Pharmacologic and Clinical Testing of a D1 Agonist for Cognitive Enhancement in Neuropsychiatric Disorders
The investigators propose to recruit individuals with schizophrenia who are symptomatically stable and already taking medications to participate in this study.
- Trial name
- NCT01519557
- Testing
- DAR-100A
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- New York State Psychiatric Institute
Fatigue
Nonpharmacological Method and Postpartum Fatigue
Postpartum fatigue is common in women after cesarean section and it affects the woman and the baby. Many noninvasive applications help to overcome this problem.
- Trial name
- NCT05201157
- Testing
- acupressure group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- resmiye kaya odabaş
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