Clinical trials: A
Hyperglycemia
Feasibility Study to Evaluate Safety and Device Performance of the Hospital Glucose Management System (HGMS)
The purpose of this study is to assess safety and device performance of the Medtronic Hospital Glucose Management System (HGMS) for up to 72-hours.
- Trial name
- MAHI (NCT01763567)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Medtronic MiniMed, Inc.
Neovascular Age-related Macular Degeneration
A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration
This is a Phase 1/Phase 2 multicenter study to evaluate the safety and efficacy of a one-time single-eye intravitreal dose of SAR402663 in participants with neovascular age-related macular degeneration.
- Trial name
- NCT06660667
- Testing
- SAR402663, Diluent
- Where
- 26 sites in United States, United Kingdom
- Volunteers
- 66 people
- Sponsor
- Sanofi
Asthma
Examining the Effects of a Remote Pulmonary Rehabilitation Program in the Severe Asthma Population.
This is a randomized control trial evaluating the effect of a novel mobile application-delivered pulmonary rehabilitation program in adult severe asthma patients.
- Trial name
- STAPLE (NCT06150300)
- Testing
- Pulmonary rehab program
- Volunteers
- 34 people
- Sponsor
- University of Saskatchewan
Antibiotics, Subcutaneous Injection
Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC)
Background: Multidrug-resistant bacteria are a major public health problem worldwide, notably due to excess mortality and an increase in the length of hospital stay.
- Conditions
- Antibiotics, Subcutaneous Injection, Daptomycin
- Trial name
- DAPTOSC (NCT04434300)
- Testing
- Daptomycin
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Femoral Neck Fractures, Osteoporosis
Complications and Functional Outcome of Displaced Femoral Neck Fractures in Patients Younger Than 70 Years
Patients younger than 70 years with a displaced femoral neck are in serious conditions. The femoral neck fracture is associated with low activity levels, hip pain and substantially reduced quality of life.
- Trial name
- NCT02085707
- Testing
- Total hip replacement arthroplasty, Closed reduction and internal fixation
- Where
- 4 sites in Norway
- Volunteers
- 118 people
- Sponsor
- University Hospital, Akershus
Diaper Dermatitis
Probiotics for Diaper Dermatitis
The goal of this randomized controlled clinical trial is to determine the effect of the probiotic OMNiBiOTiC® Panda in treating diaper dermatitis in children under the age of two years.
- Trial name
- ProDiaper II (NCT06755307)
- Testing
- OMNiBiOTiC® Panda
- Where
- Slovenia
- Volunteers
- 42 people
- Sponsor
- University Maribor
Common Cold, Sinusitis
A Study of Olynth Saline/Ectomed Nasal Drops/Spray Based Upon Previous Usage
The purpose of this study is to proactively collect customer feedback on the performance aspects and risk factors of Olynth Nasal Saline Drops/Spray and Olynth Ectomed Nasal Spray.
- Conditions
- Common Cold, Sinusitis, Hypersensitivity
- Trial name
- NCT05126407
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Postpartum Rheumatism
Efficacy and Safety of Saussurea Involucrata Liquid Tonic in Patient With Postpartum Rheumatism
This study is a multi-center, randomized, double-blinded, controlled trial with two parallel arms. The study aims to evaluate the efficacy and safety of Involucrata Liquid Tonic in patients with Postpartum Rheumatism.
- Trial name
- NCT06430307
- Testing
- Saussurea Involucrata Liquid Tonic
- Volunteers
- 128 people
- Sponsor
- Quan Jiang
Healthy Volunteers
I.V. Selonabant in Healthy Adult Subjects
This is a Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenous Selonabant in Healthy Adult Subjects Aged 18 to 30 Years
- Trial name
- NCT07211607
- Testing
- selonabant
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anebulo Pharmaceuticals
Influenza, Human, Flu, Human
Safety and Immunogenicity of Two Doses of aH5N1 Vaccine in Adult and Elderly Subjects With and Without Immunosuppressive Conditions *aH5N1:Monovalent H5N1 Influenza Vaccine
Evaluate the safety, immune response and reactogenicity of aH5N1 vaccination in adult (18 through 60 years of age) and elderly (≥61 years of age) subjects with and without immunosuppressive conditions.
- Conditions
- Influenza, Human, Flu, Human, Flu, Avian, Influenza
- Trial name
- NCT02107807
- Testing
- Novartis Investigational H5N1 vaccine, Novartis Seasonal Influenza Vaccine
- Where
- 17 sites in Australia, Germany and 1 more
- Volunteers
- 539 people, healthy volunteers welcome
- Sponsor
- Seqirus
Post Operative Pain, Laparoscopic Colorectal Surgery
Analgesic Effect of Bilateral Quadratus Lumborum Block in the End of Colorectal Laparosopic Surgery.
The primary purpose of COLOQUAL study is to demonstrate the superiority of analgesic effect of a bilateral quadratus lumborum block (QLB), performed at the end of laparoscopic colorectal surgery, compared to standard of care.
- Trial name
- Coloqual (NCT03966092)
- Testing
- Quadratus lumborum block
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Clermont-Ferrand
Psoriasis
Swiss Dermatology Network of Targeted Therapies (SDNTT)
The purpose of this study is to evaluate the long-term course of patients with psoriasis and psoriatic-arthritis in systemic treatments such as, methotrexate, cyclosporin A, fumaric acids, acitretin, systemic PUVA, etanercept…
- Trial name
- SDNTT (NCT01706692)
- Testing
- Adalimumab, Etanercept, Infliximab
- Where
- 6 sites in Switzerland
- Volunteers
- 1,121 people
- Sponsor
- Swiss Dermatology Network for Targeted Therapies
Sacro Iliac Joint Pain, Low Back Pain
Effectiveness Of Alcohol Addition In Ultrasound-Guided Periarticular Sacroiliac Joint Injection
The aim of this work is to evaluate the efficacy of adding alcohol to local anesthetics and steroids to provide pain relief in patients with sacroiliac joint pain.
- Conditions
- Sacro Iliac Joint Pain, Low Back Pain, Alcohol Induced Neurolysis
- Trial name
- NCT07151027
- Testing
- sacroiliac joint injection
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Fayoum University
Relapsed/Refractory B-cell Malignancies
UBX-303061 in Subjects With Relapsed/Refractory B-Cell Malignancies
This is a first-in-human Phase 1a/1b multicenter, open-label study designed to evaluate the safety and anti-cancer activity of UBX-303061 in patients with relapsed/refractory B-cell malignancies.
- Trial name
- NCT06590961
- Testing
- UBX-303061
- Where
- 11 sites in United States, Poland and 1 more
- Volunteers
- 94 people
- Sponsor
- Ubix Therapeutics, Inc.
Breast Cancer
An Innovative Smartphone Application for Adverse Event Management During Breast Cancer Adjuvant Chemotherapy
The aim of this study is to evaluate benefits of the app in breast cancer patients receiving the docetaxel, doxorubicin, and cyclophosphamide (TAC) chemotherapy.
- Trial name
- NCT05258461
- Testing
- use of a smartphone app for adverse event management, conventional adverse event management
- Volunteers
- 108 people
- Sponsor
- Peking Union Medical College Hospital
Menopause
Effects of a Recreational Team Handball-based Programme on Health and Physical Fitness of Postmenopausal Women
This study aimed at determining the short- (16 weeks) and long-term (36 weeks) health and physical fitness effects and adherence of recreational team handball training for postmenopausal women without previous experience with the…
- Trial name
- H4HW (NCT05292261)
- Testing
- Recreational team handball
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- University Institute of Maia
Knee Osteoarthritis
Ultrasonographic Evaluation of Osteoarthritis.
Assessment of the effectiveness of ultrasonography in correlation to conventional imaging for the detection of the definite grading of knee osteoarthritis.
- Trial name
- NCT07001761
- Testing
- Ultrasound/ x rays
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
HRV
Measuring Accuracy of Wristband for Registration of ECG RR-Intervals for One Hand, SenceBand in Comparison to Holter
The purpose of the study is to evaluate the measuring accuracy of the Wristband for registration of ECG RR intervals for one hand, SenceBand icompared to the Holter monitor (LabTech Ltd).
- Trial name
- NCT03747861
- Testing
- SenceBand
- Where
- Ukraine
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Planexta, Inc
Taste Perception, Orthodontic Appliance Complication
Alteration of Taste Among Orthodontic Patients Following Clear Aligners Treatment
The goal of this clinical trial is aimed to assess the gustatory perception and alteration in patients using either clear aligners or fix orthodontics treatment in orthodontic patient aged +18 years and not have any endocrine…
- Conditions
- Taste Perception, Orthodontic Appliance Complication, Fixed Orthodontic Appliances
- Trial name
- NCT06124742
- Testing
- clear aligners
- Where
- Saudi Arabia
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Osteoporosis
A Retrospective Comparison Between CPS and HC Techniques for Osteoporotic Fractures in the Thoracic or Lumbar Spine
Cement-augmented pedicle screws (CPS) and hybrid construct (HC) consisting of pedicle screws and additional hooks are common methods in osteoporotic fracture of the thoracic and lumbar spine.
- Trial name
- NCT05130242
- Testing
- Cement-augmented Pedicle Screws (CPS), Hybrid Construct (HC)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
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