Clinical trials: A
Primary Hypertension
Effects of Telmisartan/Hydrochlorothiazide Treatment in Hypertensive Patients Under Real-life Setting
One of the most common adverse effects resulting from the therapy with thiazides, thiazide-like diuretics and loop diuretics is increased potassium secretion.
- Trial name
- POTASSIUM (NCT01392534)
- Testing
- Telmisartan/hydrochlorothiazide (Pritor Plus, BAY98-7103)
- Where
- Poland
- Volunteers
- 1,586 people
- Sponsor
- Bayer
Gastric Cancer
A Feasibility Study for Convernsion Therapy Using S1/Paclitaxel Chemotherapy Plus Apatinib in ELM Gastric Cancer
The prognosis of Extensive lymph nodes metastatic(ELM) gastric cancer is poor. Chemotherapy occasionally converts it to a resectable cancer.
- Trial name
- NCT03258034
- Testing
- SPA
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Thyroid Neoplasms, Hypothyroidism
Individual Dosing of Levothyroxine After Thyroidectomy
Recently, Zaborek et al. raised a Poisson regression model for levothyroxine(LT4) dosing scheme to predict individual dose of LT4 after thyroidectomy: daily LT4 dose=e[2.02+0.01(W)-0.0037(A…
- Conditions
- Thyroid Neoplasms, Hypothyroidism, Surgery
- Trial name
- NCT05240911
- Testing
- Levothyroxine Sodium Tablets
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Palsy (CP), Activities of Daily Living
NAO Robot in Pediatric Occupational Therapy
Cerebral Palsy (CP) is a non-progressive neurological disorder that affects movement and posture, often impairing upper extremity function and daily activity performance.
- Trial name
- NAO Robot (NCT07283211)
- Testing
- Occupational Therapy Intervention, NAO Robot-Assisted Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ankara Medipol University
Pain
Compare the Efficacy and Safety of Norspan to Tramadol/Acetaminophen With Prolonged Postoperative Pain (PASSION)
The purpose of this study is to compare the efficacy and safety of buprenorphine transdermal system to tramadol/acetaminophen.
- Trial name
- NCT01983111
- Testing
- buprenorphine, tramadol/acetaminophen
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Mundipharma Korea Ltd
Benign Prostate Hyperplasia, Erectile Dysfunction
A Study of Tadalafil in Men With Benign Prostatic Hyperplasia (BPH) and Erectile Dysfunction (ED)
The purpose of this study is to see whether tadalafil can reduce the signs and symptoms in men with Erectile Dysfunction (ED) and Benign Prostatic Hyperplasia-Lower Urinary Tract Symptoms (BPH-LUTS) and improve their quality of…
- Trial name
- NCT01937871
- Testing
- 5 mg Tadalafil, 0.2 mg Tamsulosin
- Where
- 14 sites in China
- Volunteers
- 909 people
- Sponsor
- Eli Lilly and Company
Cardiac Arrhythmia
EnSite Precision Observational Study
This document is a clinical investigation plan (CIP) for the EnSite Precision Observational Study. This clinical study is intended to quantify and characterize the usage of the EnSite Precision™ Cardiac Mapping System (Software…
- Trial name
- NCT03260244
- Testing
- cardiac mapping and radiofrequency ablation procedure
- Where
- 7 sites in United States
- Volunteers
- 1,065 people
- Sponsor
- Abbott Medical Devices
Postoperative Pain, Cardiac Surgery
Parasternal Block Versus Wound Infiltration for Pain After Median Sternotomy:A Salivary Opiorphin-Based Study
This study evaluated the effects of parasternal block and wound site infiltration on postoperative pain in patients undergoing median sternotomy.
- Conditions
- Postoperative Pain, Cardiac Surgery, Median Sternotomy
- Trial name
- NCT07621744
- Testing
- Parasternal blocks, Wound Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk University
Class II Malocclusion
Evaluation of the Levels of Pain, Discomfort, and Functional Impairment With Two Techniques of Retraction
Thirty-eight patients requiring extraction of maxillary first premolars will participate in the study. They will be divided randomly into two groups: an en-masse retraction group and a two-step group.
- Trial name
- NCT05652244
- Testing
- Mini-implants, Transpalatal arche (TPA)
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Suicide
THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers
Suicide is a major public health concern in the United States, with more than 1.4 million adults attempting suicide and nearly 50,000 adults dying by suicide each year.
- Trial name
- THRIVE (NCT07784634)
- Testing
- Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE), Center Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- University of Alabama at Birmingham
Schizophrenia and Schizoaffective Disorder
A Trial of Group Cognitive Behavioral Therapy for Psychosis (the Feeling Safe Programme)
Schizophrenia is a serious psychiatric disorder characterized by delusions, hallucinations, negative symptoms and disorganized behaviour.
- Trial name
- NCT07408934
- Testing
- Cognitive Behavioral Therapy for Psychosis
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Breast Cancer Female
Immediate Breast Reconstruction Following Mastectomy (IRMA)
Based on data from the US Surveillance, Epidemiology and End Result Program (SEER), the rates of nipple-sparing mastectomy (NSM) have risen 202% since 2009.
- Trial name
- IRMA (NCT04390529)
- Testing
- quality-of-life questionnaire: BREAST-Q
- Where
- 15 sites in Switzerland
- Volunteers
- 515 people
- Sponsor
- Thurgau Breast Center
Smoking Cessation
Early Health Warning Intervention in Tobacco Control
This is a multi-center, randomized, controlled intervention clinical trial. A total of 1000 current smokers with rapid decline in lung function will be recruited and equally divided into two groups, comprehensive smoking…
- Trial name
- NCT04996329
- Testing
- early health warning intervention
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Erectile Dysfunction
Vardenafil Orodispersible Tablet (ODT) Versus Placebo in Males With Erectile Dysfunction, 50% of Whom Are to be 65 Years or Older.
This study investigates the safety and efficacy of a new dosage form of Vardenafil, an orodispersible tablet (ODT), and compares it to the safety and efficacy of a placebo (inactive) tablet in the treatment of erectile…
- Trial name
- NCT00655629
- Testing
- Vardenafil ODT (STAXYN, BAY38-9456)
- Where
- 40 sites in United States, Australia and 2 more
- Volunteers
- 339 people
- Sponsor
- Bayer
Psychological Well-being, Childbirth
Supportive Care During Childbirth and Well-being
The aim of this study is to evaluate the effects of continuous supportive care (ICSC) at birth on some parameters of maternal psychological well-being.
- Conditions
- Psychological Well-being, Childbirth, Care Pattern, Maternal
- Trial name
- NCT05333653
- Testing
- Continouse supportive care, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mersin University
Healthy Non-dependent, Recreational Sedative Users, Abuse Potential
A Study to Determine the Abuse Potential of Seltorexant Compared to Suvorexant and Zolpidem
The purpose of this study is to evaluate the abuse potential of seltorexant compared to placebo and two active comparators (zolpidem and suvorexant) in non-dependent, recreational sedative users.
- Trial name
- NCT05106153
- Testing
- Suvorexant, Zolpidem, Seltorexant
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Steatosis
Clinical Validation of a Raman Spectroscope to Determine Hepatic Fat Content
Fatty liver disease including liver steatosis (fat deposition) is a major health problem worldwide. It is considered pathological when fat accumulation exceeds 5% of the liver weight.
- Trial name
- NCT02621853
- Testing
- Raman spectroscopy of the liver
- Volunteers
- 3 people
- Sponsor
- Nova Scotia Health Authority
Hemophilia, Hemophilia A
ATHN 8: Previously Untreated Patients (PUPs) Matter Study
This is a multi-center cohort study of approximately 250 previously untreated patients (PUPs) with congenital moderate to severe hemophilia A or B in a network of up to 50 US Hemophilia Treatment Centers (HTCs).
- Conditions
- Hemophilia, Hemophilia A, Hemophilia B, Hemophilia A With Inhibitor
- Trial name
- NCT03818529
- Where
- 27 sites in United States
- Volunteers
- 237 people
- Sponsor
- American Thrombosis and Hemostasis Network
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Endometriosis, Pain
Is Repetitive Transcranial Magnetic Stimulation Effective in Reducing Endometriosis-associated Pain
The goal of this research is to improve pain outcomes for the over 500K Canadian women, girls and gender-diverse individuals who are newly diagnosed with endometriosis each year.
- Trial name
- NCT06333353
- Testing
- Real RepetitiveTranscranial Magnetic Stimulation 5 sessions, Real RepetitiveTranscranial Magnetic Stimulation 10 sessions
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- University of Ottawa
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