Clinical trials: ACL Injuries
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear
Effects of Whole Body Vibration on Quadriceps Function, Landing Biomechanics, and Performance in Individuals With ACL Reconstruction
Individuals who undergo anterior cruciate ligament reconstruction (ACLR) are at heightened risk of secondary anterior cruciate ligament (ACL) injury (e.g. additional injury to the ACL in either knee).
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear, ACL Injury, ACL Tear
- Trial name
- NCT07681193
- Testing
- Whole body vibration (WBV)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of North Carolina, Chapel Hill
Telerehabilitation, Anterior Cruciate Ligament Injuries
Telerehabilitation for Anterior Cruciate Ligament Reconstruction - TAR Program in Adolescents
Anterior cruciate ligament (ACL) injuries are common in adolescents and its prevalence has increased over the years, especially with more adolescents engaging in physical activities and competitive sports.
- Conditions
- Telerehabilitation, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament
- Trial name
- TAR (NCT05799235)
- Testing
- Telerehabilitation TAR program using a mobile application, Standard rehabilitation sessions
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
ACL Injury
Influence of Combined Double-Bundle ACL Reconstruction With Lateral Retinacular Release to Prevent Patellofemoral Malalignment in Isolated ACL Rupture
Anterior knee pain which might be due to patellofemoral malalignment is an inevitable post operative complication after an ACL reconstruction (ACLR).
- Trial name
- NCT06004297
- Testing
- ACL reconstruction
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
ACL, Anterior Cruciate Ligament Injuries
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor…
- Trial name
- NCT05720949
- Testing
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Tear, Osteoarthritis, Knee
Long Term Clinical and Radiographical Outcomes of Different Anterior Cruciate Ligament Reconstruction Techniques
The purpose of this study is to evaluate the long-term results of various anterior cruciate ligament reconstruction techniques. This assessment is necessary for the current context of anterior cruciate ligament research as…
- Trial name
- NCT05088278
- Testing
- Anatomical single bundle ACL reconstruction with hamstrings, Anatomical single bundle ACL reconstruction with patellar tendon, ACL reconstruction with over the top plus lateral plasty technique
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Anterior Cruciate Ligament Injuries Posterior Cruciate Ligament Tear
Interference Screw Mectascrew-B Postmarket Study
An observational prospective study with the aim to assess the clinical outcomes at 1year after surgery for a specific composite IS (Medacta Mectascrew B) in the reconstructive treatment of ruptured ACL or PCL by means of an…
- Trial name
- NCT06166784
- Testing
- Mectascrew B
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- Medacta International SA
Rupture of Anterior Cruciate Ligament
Multicenter Orthopaedics Outcomes Network for ACL Reconstructions
The purpose of this study is to determine the effect of modifiable risk factors on knee function, osteoarthritis, and re-rupture of the anterior cruciate ligament (ACL) following ACL reconstruction.
- Trial name
- NCT00463099
- Where
- 8 sites in United States
- Volunteers
- 3,294 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Injuries, Reconstruction
Return to Sports After ACLR
Patients who were surgically treated with ACL reconstruction at a single clinic between 2013 and 2018 will be approached by a questionnaire regarding their return to sport after surgery.
- Trial name
- RTSACL (NCT04862013)
- Where
- Switzerland
- Volunteers
- 133 people
- Sponsor
- crossklinik AG
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Injuries
Wearable Vibration Effect on Biomechanics and Biomarkers After ACL Reconstruction
Anterior cruciate ligament (ACL) injuries account for up to 25% of knee injuries, it is estimated that 32,000-400,000 new cases of ACL tears occur in the USA every year.
- Trial name
- NCT05001594
- Testing
- Active vibratory knee device
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Technion, Israel Institute of Technology
Anterior Cruciate Ligament Injury
Effects of Elastic Therapeutic Tape on Biomechanical Changes of Knee Joint During Drop Vertical Jump in ACL Injuries
The purpose of this study to investigate joint angle and joint moment in flexion-extension, adduction-abduction and internal -external rotation of elastic therapeutic tape and elastic therapeutic tape are effective in…
- Trial name
- NCT02271061
- Testing
- Kinesio tape, Control tape
- Volunteers
- 8 people
- Sponsor
- Mahidol University
ACL Injury
ADC in Assessing Femoral Tunnel Position
To examine the consistency between postoperative CT scan and intraoperative arthroscopic measurement in evaluating femoral tunnel position for anterior cruciate ligament （ACL）reconstruction，both using the apex of the deep…
- Trial name
- NCT04937517
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Machine Learning
MUSCLE-ML: Multimodal Integration of Muscle Strength, Structure by Machine Learning for Precision Rehabilitation After ACL Injury
The goal of this clinical trial is to use machine learning (ML) to predict functional recovery by integrating muscle-related factors and other relevant parameters for identification of non-responders to conventional…
- Trial name
- NCT07284771
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Anterior Cruciate Ligament Injury
Effects of a Targeted Prevention Program on Change-of-Direction Biomechanics and Performance in Elite Female Soccer Players
Anterior cruciate ligament (ACL) injuries are common in female soccer and frequently occur during change-of-direction (COD) movements without contact.
- Trial name
- PREV-COD-FF (NCT07523178)
- Testing
- Targeted Injury Prevention Program
- Where
- Belgium
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liege
Anterior Cruciate Ligament Injury
Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of anterior cruciate ligament reconstruction: a treatment…
- Trial name
- NCT03818932
- Testing
- Celecoxib, Hydrocodone-Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Knee Ligament Injury
TEL and Clam Shell Exercises Affect After ACL
The purpose of this study to determine the effects of the addition of isolated hip strengthening exercises to traditional rehabilitation after Anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT05856071
- Testing
- goniometer, clamshells exercises, traditional physical therapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Rupture
Femoral Tunnel Position on Conventional MRI After Anterior Cruciate Ligament Reconstruction-Transtibial Technique Versus Transportal Technique
The position of the femoral tunnel in anterior cruciate ligament (ACL) reconstruction has been assessed on three dimensional CT (3D-CT) scan or in cadaveric study.
- Trial name
- NCT01513434
- Testing
- transtibial technique, Transportal technique, anterior cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- National Police Hospital
ACL Injury, Gait
The Influence of Running to ACL Deficiency
The aim of this study is to investigate the influence of running to kinematic parameters of patients with anterior cruciate ligament.
- Trial name
- NCT03135600
- Testing
- Procedure
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command