Clinical trials: ACL Injuries
Anterior Cruciate Ligament Injuries
Can Sensorimotor Function Predict Graft Rupture After ACL Reconstruction
In this longitudinal prospective cohort study including young people with anterior cruciate ligament (ACL) reconstruction, the investigators will evaluate if poor sensorimotor function at baseline can predict 1) graft rupture 2)…
- Trial name
- NCT04162613
- Testing
- Different measures of muscle function such as muscle strength, hop tests, postural orientation and muscle activation
- Where
- Sweden
- Volunteers
- 201 people
- Sponsor
- Umeå University
Anterior Cruciate Ligament Rupture
Absorbable Interface Screw Clinical Trial
Validation of the safety and efficacy of absorbable interface screws for clinical use
- Trial name
- NCT05431790
- Testing
- Absorbable interface screws manufactured by Natong Biotechnology, Absorbable interface screws manufactured by INION.
- Volunteers
- 86 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture, Electroencephalography
Functional Connectivity After Anterior Cruciate Ligament Reconstruction
Background: Despite surgical reconstruction and rehabilitation, individuals after a primary anterior cruciate ligament injury have a significantly increased risk of relapse.
- Conditions
- Anterior Cruciate Ligament Rupture, Electroencephalography, Injuries
- Trial name
- FCACLR (NCT05487768)
- Testing
- EEG measurement
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Anterior Cruciate Ligament Injuries
Clinical and Radiological Evaluation of ACL Reconstruction Results
The study is intended to include all patients who will undergo surgical reconstruction of the anterior cruciate ligament (ACL). The patients will be monitored and evaluated preoperatively and also at 6 months and 1 years after…
- Trial name
- NCT05504018
- Testing
- ACL reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Samsun University
ACL Tear
Safe Return to Play After ACL Reconstruction
Recent studies report that as few as 44% of athletes undergoing ACL reconstruction were able to return to their prior level of competitive level of sports.
- Trial name
- NCT04827264
- Testing
- Safe Return to Play Following ACL Reconstruction Checklist
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Rothman Institute Orthopaedics
Anterior Cruciate Ligament Injuries
Operant Conditioning After ACL Reconstruction
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT05519345
- Testing
- Operant Conditioning, Control
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
ACL - Anterior Cruciate Ligament Rupture
Microbiological Molecular Profile of the Knee Joint During Primary Reconstruction or Revision Surgery of the ACL
Anterior cruciate ligament (ACL) reconstructions are common surgical procedures, but a significant number fail for reasons that are not fully understood.
- Trial name
- INFECTIOGEN (NCT07009392)
- Testing
- NGS Analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
ACL Tear
ACL Bone Health and Loading Study
The purpose of this study is to look at the effects of bone density on lower extremity loading mechanics using Blood Flow Restriction (BFR) to provide the control group for bone health.
- Trial name
- ACLBONE (NCT04682392)
- Testing
- Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Candice Dunkin, MS, LAT, ATC
Anterior Cruciate Ligament Rupture
The Effects of Remnant-Preserving Anterior Cruciate Ligament Reconstruction on Proprioception and Functionality
Anterior cruciate ligament (ACL) reconstruction is a frequently performed surgical procedure to stabilize the knee joint biomechanically.
- Trial name
- NCT05057442
- Testing
- Proprioception assessment, functionality assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Acibadem University
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
ACL Reconstruction, ACL Injury
Validity of the SHD-LESS Scale After ACL Reconstruction
After anterior cruciate ligament reconstruction (ACL-R), Single Hop for Distance (SHD) performance aids in decision-making, particularly for return-to-sport assessments.
- Trial name
- ACL-LESS (NCT06829849)
- Testing
- Landing error assessment during a SHD task using the SHD-LESS scale
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Rupture
Obtain Safety and Effectiveness of CT-ACL001, a Regenerative Ligament Using Biological Tissue, in ACLR
A randomized, multicenter study comparing the safety and efficacy of CT-ACL001, a regenerative ligament, with standard treatment in anterior cruciate ligament reconstruction
- Trial name
- NCT07129694
- Testing
- Anterior cruciate ligament reconstruction
- Where
- 6 sites in Japan
- Volunteers
- 64 people
- Sponsor
- CoreTissue BioEngineering Inc.
ACL Injury
A Prehab Strengthening Program Prior to ACL Surgery on Lower Limb Structure and Function
Atrophy and weakness are ubiquitous after a ACL rupture and associated with a worsened long-term recovery of individual capacities, despite surgery and rehabilitation.
- Trial name
- ACL-Strong (NCT05374382)
- Testing
- Strengthening, Conventional
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Université de Nantes
Anterior Cruciate Ligament Injuries
The Impact of Germanium-Embedded Knee Brace on Patient Recovery After ACL Reconstruction
Anti-inflammatory brace technology has demonstrated superior clinical outcomes in the management of knee osteoarthritis and accelerate recovery time for Major League Soccer players.
- Trial name
- NCT05068297
- Testing
- Incrediwear Germanium-Embedded Knee Brace following ACL reconstruction, Replica Knee Brace
- Volunteers
- 100 people
- Sponsor
- Total Sports Medicine & Orthopedics
Anterior Cruciate Ligament Rupture
Induced ACL Healing With the Ligamys Technique: a Prospective, Multicenter Observational Case Series
The purpose of this study is to evaluate the safety and effectiveness of the Ligamys technique for the treatment of acute ruptures of the anterior cruciate ligament in a multicenter routine clinical setting.
- Trial name
- Ligamys (NCT02203214)
- Testing
- Ligamys
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 110 people
- Sponsor
- Mathys Ltd Bettlach
ACL, Meniscus Lesion
THE EFFECT OF RAMP LESION REPAIR ON RETURN TO SPORTS IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Purpose/reason of the research: The anterior cruciate ligament (ACL) is an important ligament in maintaining knee function. In patients with anterior cruciate ligament (ACL) injury, concomitant intra-articular lesions are usually…
- Conditions
- ACL, Meniscus Lesion, Sport Injury
- Trial name
- NCT05048420
- Testing
- surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Medipol University
ACL, Anterior Curciate Ligament
Risk of Osteoarthritis of the Knee at Least 5 Years After ACL Reconstruction: Comparative Study Between an Isolated ACL Reconstruction and a Reconstruction Combining ACL and ALL
The main objective of this study is to compare, with a minimum follow-up of 5 years, the prevalence of femoro-tibial osteoarthritis after an isolated ACL ligamentoplasty or after an ACL ligamentoplasty combining ACL and ALL.
- Conditions
- ACL, Anterior Curciate Ligament, Anterolateral Ligament, Knee Injuries
- Trial name
- NCT05123456
- Testing
- Radiography
- Where
- France
- Volunteers
- 180 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
ACL - Anterior Cruciate Ligament Rupture
Correlation Study Between the Classification of Arthrogenic Motor Inhibition (AMI) and Clinical Assessment After ACL Rupture
The goal of this interventional study is to measure medial vastus inhibition and associate it with AMI classification in patients with ACL rupture.
- Trial name
- AMIVAL (NCT06945133)
- Testing
- Clinical testing
- Where
- France
- Volunteers
- 90 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.
The goal of this clinical trial is to evaluate the effectiveness of adding Blood Flow Restriction (BFR) therapy to a standardized rehabilitation protocol in patients undergoing postoperative rehabilitation following anterior…
- Trial name
- NCT06762392
- Testing
- Blood Flow Restriction, Standard Rehabilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Valencia