Clinical trials: ACL Surgery, open to volunteers
Tendinopathy, Musculoskeletal Diseases or Conditions
Human Tendon Tissue Collection
The goal of this study is to improve understanding of tendon health and disease by using surplus tendon tissue that is routinely removed during planned orthopaedic surgeries in adults.
- Conditions
- Tendinopathy, Musculoskeletal Diseases or Conditions, ACL Surgery, Achilles Tendon Surgery
- Trial name
- NCT07606092
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- Queen Mary University of London
Anterior Cruciate Ligament Injuries, Postoperative Pain
Multimodal Analgesia vs. Femoral Block in ACL Surgery
This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative
- Trial name
- MAPvsFTB (NCT06936995)
- Testing
- Preemptive Multimodal Intravenous Analgesia, Femoral Triangle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara University
Anterior Cruciate Ligament Reconstruction
Tourniquet vs. Dual-flow Arthroscopy Sheath in Anterior Cruciate Ligament (ACL) Reconstruction
This is a prospective randomized study comparing tourniquet use versus a dual-flow arthroscopy sheath in Anterior Cruciate Ligament (ACL) reconstruction surgery.
- Trial name
- RELICA (NCT06819696)
- Testing
- ACL reconstruction with a dual-flow arthroscopy sheath, ACL reconstruction with a thigh tourniquet
- Where
- 3 sites in France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
ACL Injury
Effect of Contralateral NMES on Quadriceps Activation After ACL Injury or Surgery
A major complication after cruciate ligament injury and surgery is arthrogenic muscle inhibition of the quadriceps, which is characterised by a deficit in voluntary muscle activation in the affected leg.
- Trial name
- ACLQuadAct (NCT07156734)
- Testing
- Neuromuscular Electrical Stimulation
- Volunteers
- 25 people
- Sponsor
- Schulthess Klinik
ACL Injury
Functional Movement Training Versus Functional Stability Training in Post-ACL Surgery
This randomized controlled trial study will include 32 athletes aged 18-35 who had ACL surgery. After surgery, participants will be selected and assigned randomly to the Functional Movement Training or Functional Stability…
- Trial name
- NCT07725016
- Testing
- Functional Movement training, Functional stability training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament (ACL) Revision Surgery: French National Study
This is a national multicentric study led by the French Arthroscopy Society (SFA) evaluating clinical practice in anterior cruciate ligament (ACL) revision surgery (epidemiological data, morphological data, operative data…
- Trial name
- NCT06379308
- Testing
- questionaries, datas of medical record
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Anterior Cruciate Ligament Reconstruction
Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction
Scientific Research Question Overall Purpose: Regarding rehabilitation after anterior cruciate ligament reconstruction (ACLR), there is a knowledge gap - a lack of evidence.
- Trial name
- NCT06318039
- Testing
- Novel program, Traditional program
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Linnaeus University
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Anterior Cruciate Ligament Rupture
Assessing the Efficacy of a Preoperative Navigation System in Anterior Cruciate Ligament Reconstruction
The ACL surgery robot features a preoperative navigation system that enhances the precision of bone tunnel placement. As the first dual-bundle reconstruction surgical robot developed in China, it integrates advanced technology to…
- Trial name
- NCT06858930
- Testing
- ACL footprint localization after preoperative navigation executed by robotic arm, ACL footprint localization after preoperative navigation executed by rmanual execution
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Anterior Cruciate Ligament Injury, Tunneling Technique
Evaluation of the Correlation Between Bone Tunnel Projection Placement and Clinical Outcomes in Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) rupture is a common and clinically significant injury, particularly among young, active, and athletic adults, and may lead to knee instability and functional impairment.
- Conditions
- Anterior Cruciate Ligament Injury, Tunneling Technique, Tendon Graft; Complication, Mechanical
- Trial name
- NCT07876635
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries
Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament Reconstruction (ACLR) Using Peroneus Longus Tendon Graft (PL-ACL-2025)
This clinical trial aims to investigate the correlation between psychological readiness, knee function, and isokinetic performance after anterior cruciate ligament reconstruction (ACLR) using the Peroneus Longus tendon graft…
- Conditions
- Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries, Knee Injuries
- Trial name
- PL-ACLR (NCT07201597)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Reconstruction, Pain Management
Comparison of Analgesic Effects of ACB Versus ACB Combined With BiFeS Block in ACL Reconstruction Surgery
Anterior cruciate ligament (ACL) reconstruction is commonly associated with moderate to severe postoperative pain, particularly during the early postoperative period and rehabilitation.
- Trial name
- NCT07859397
- Testing
- Adductor Canal Block, BiFeS Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara Etlik City Hospital
ACL Injury
Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries
Currently, most patients with an anterior cruciate ligament injury undergo surgery. There is a general belief that surgical reconstruction is necessary to safely return to sports and to prevent early knee osteoarthritis or…
- Trial name
- IODA (NCT05747079)
- Testing
- Rehabilitation, Optional delayed anterior cruciate ligament reconstruction, Immediate anterior cruciate ligament reconstruction
- Where
- Belgium
- Volunteers
- 280 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Quadriceps Atrophy, ACL Reconstruction
Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?
The purpose of this study is to evaluate the effectiveness of physical therapy (PT) plus BFR training compared to PT alone (without BFR training) after ACL reconstruction in patients who require extended limited weight bearing…
- Trial name
- NCT03096366
- Testing
- Blood flow restriction, Physical therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under SA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under spinal anesthesia.
- Trial name
- NCT06048874
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under GA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under general anesthesia.
- Trial name
- NCT06048848
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anterior Cruciate Ligament Rupture
Cross Bracing Protocol Versus Surgery for Acute Anterior Cruciate Ligament Rupture
The aim of the EMBRACE clinical trial is to compare outcomes (knee pain, symptoms, function and quality of life) between people with anterior cruciate ligament (ACL) rupture who are managed with either a novel bracing protocol…
- Trial name
- EMBRACE (NCT06956339)
- Testing
- Early anterior cruciate ligament surgery, Novel bracing protocol
- Where
- Australia
- Volunteers
- 180 people
- Sponsor
- University of Melbourne
Anterior Cruciate Ligament Tear, Medial Collateral Ligament
A Study to Evaluate the Incrediwear Products Immediately After ACL Repair
To assess the benefits of using the Incrediwear knee products after ACL or ACL+MCL arthroscopic surgery, on the postoperative pain, range of motion and effusion.
- Trial name
- NCT06668376
- Testing
- Leg Sleeve
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Cruciate Ligament Reconstruction
Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction
Aim: Comparison of tendon to bone ingrowth in bone tunnels and intra-articular remodeling of the graft after anterior cruciate ligament surgery with a muscle-tendon graft and those with a tendon graft.
- Trial name
- CandyStripe (NCT07404046)
- Testing
- ACL reconstruction
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Dubrava