Clinical trials: ACS
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Registry of Bleeding Risk in Real World Chinese Acute Coronary Syndrome Patients-II
The present study was designed to observe the incidence of bleeding events and characteristics of bleeding and exploratively analyse bleeding related biomarkers and gene polymorphisms in ACS patients undergoing PCI.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Bleeding
- Trial name
- NCT03402711
- Where
- China
- Volunteers
- 5,500 people
- Sponsor
- Chinese PLA General Hospital
Cardio Vascular Disease, Acute Coronary Syndromes (ACS)
Qatar Cardiometabolic Retrospective Cohort-Analysis Using Artificial Intelligence
Cardiovascular disease is the leading cause of death worldwide, and individuals with diabetes or other cardiometabolic conditions are at increased risk of adverse cardiovascular outcomes.
- Conditions
- Cardio Vascular Disease, Acute Coronary Syndromes (ACS), Type 2 Diabetes, Pre Diabetes
- Trial name
- QCRC-AI (NCT07515807)
- Where
- Qatar
- Volunteers
- 10,000 people
- Sponsor
- Weill Cornell Medical College in Qatar
Acute Coronary Syndrome
Paradigm Shift in the Treatment of Patients With ACS
This protocol describes a pilot study intended to test the hypothesis that patients with acute coronary syndrome (ACS) caused by plaque erosion can be stabilized by effective antithrombotic treatment without stent implantation…
- Trial name
- NCT02041650
- Testing
- Ticagrelor
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Yu Bo
Acute Coronary Syndrome
Positive Psychology for ACS Patients: a Factorial Design Study
This trial is part of a multi-phase study to develop and test positive psychology (PP) interventions in patients hospitalized for an acute coronary syndrome (ACS).Using a factorial design, the investigators will: (a) assess the…
- Trial name
- PEACEIII (NCT02754895)
- Testing
- Positive Psychology (PP), Motivational Interviewing (MI)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Massachusetts General Hospital
Coronary Artery Disease, Acute Coronary Syndrome
Shanghai Registry of Acute Coronary Events
SRACE is an multicenter observational database of outcomes for patients who are hospitalized with an acute coronary events. SRACE includes over 20 hospitals in Shanghai China that have enrolled a total of more than 3,000 patients…
- Trial name
- NCT00713557
- Testing
- drug-eluting stent, Tirofiban
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Acute Myocardial Infarction
Effect of the Biomarker Copeptin in Managing Patients With Suspected Acute Coronary Syndrome (ACS)
Acute chest pain is commonly known to be the classic symptom of acute myocardial infarction. Of the many patients which visit the Emergency Department because of chest pain, less than half do actually suffer from an acute…
- Trial name
- BiC-8 (NCT01498731)
- Testing
- Discharge home
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 902 people
- Sponsor
- Charite University, Berlin, Germany
Stable Angina (SA), Unstable Angina (UA)
Breaking Fasts Ahead of Cardiac Caths
The goal of this clinical trial is to find out whether fasting is necessary before urgent inpatient cardiac catheterizations. For patients presenting with urgent heart-related pain or even mild heart attacks, researchers want to…
- Conditions
- Stable Angina (SA), Unstable Angina (UA), NSTEMI - Non-ST Segment Elevation MI
- Trial name
- BACON-RCT (NCT06996639)
- Testing
- Non-Fasting, Fasting
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of South Florida
Liver Surgery, Hepatectomy
ACS-NSQIP Calculator for Liver Surgery
The American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) calculator has been endorsed by the surgeons' community to counsel patients and relatives regarding estimated postoperative…
- Conditions
- Liver Surgery, Hepatectomy, Outcome After Hepatectomy
- Trial name
- NCT03793933
- Testing
- Liver resection
- Volunteers
- 450 people
- Sponsor
- Humanitas Clinical and Research Center
Preterm Delivery
A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome
The hypothesis is that administration of two courses of antenatal corticosteroids, compared to one course, will show a 40% reduction in the incidence of composite neonatal morbidity in patients delivering prior to 34 weeks'…
- Trial name
- ACS (NCT00201643)
- Testing
- Betamethasone or Dexamethasone (2nd course of ACS)
- Where
- 22 sites in United States
- Volunteers
- 437 people
- Sponsor
- Obstetrix Medical Group
Acute Coronary Syndrome
Effect of CER-001 on Atherosclerosis in Acute Coronary Syndrome (ACS) Patients - Efficacy and Safety: The CHI SQUARE Trial
Cardiovascular disease remains the most pressing healthcare issue for developed countries and is becoming so for developing countries. There are a number of chronic therapies available for long-term management of risk.
- Trial name
- CHI SQUARE (NCT01201837)
- Testing
- CER-001
- Where
- 47 sites in United States, Canada and 2 more
- Volunteers
- 507 people
- Sponsor
- Cerenis Therapeutics, SA
Acute Coronary Syndrome, Physical Inactivity
Online Tai Chi Plus Fitbit After ACS
This projects studies the role of tai chi exercise and wearable fitness trackers to promote physical activity in acute coronary syndrome (ACS) survivors.
- Trial name
- Mind2Move (NCT05699642)
- Testing
- Tai chi + wearable
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Non ST Segment Elevation Acute Coronary Syndrome
COLchicine On-admission to Reduce Inflammation in Acute Coronary Syndrome (COLOR-ACS)
Since colchicine is known to have anti-inflammatory effects and inflammation is an early component of acute coronary syndrome (ACS), this study aims to evaluate the acute effects of low-dose colchicine, in addition to…
- Trial name
- COLOR-ACS (NCT05250596)
- Testing
- Colchicine, Atorvastatin
- Where
- 3 sites in Italy
- Volunteers
- 182 people
- Sponsor
- Azienda USL Toscana Centro
Coronary, Coronary Artery Disease
CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS
The CAPRA-EVO trial is a single-center, randomized, open-label study with blinded endpoint assessment comparing early evolocumab plus standard lipid-lowering therapy versus standard-of-care lipid-lowering therapy in patients with…
- Trial name
- CAPRA-EVO (NCT07612774)
- Testing
- Evolocumab, Serial photon-counting coronary computed tomography angiography, Standard Lipid-Lowering Therapy
- Where
- 2 sites in China
- Volunteers
- 232 people
- Sponsor
- West China Hospital
Acute Coronary Syndrome (ACS)
Prasugrel Switching Study in Patients With Acute Coronary Syndrome (ACS) Who Underwent Percutaneous Coronary Intervention (PCI)
This Phase IV, multicenter trial is designed to assess the efficacy of prasugrel in preventing the formation of blood clots in Taiwanese patients with ACS who have been treated with PCI.
- Trial name
- NCT03672097
- Testing
- Prasugrel
- Where
- 10 sites in Taiwan
- Volunteers
- 204 people
- Sponsor
- Daiichi Sankyo Taiwan Ltd., a Daiichi Sankyo Company
Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome
Add-on Cangrelor in STEMI-triggered Cardiac Arrest
In patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary angioplasty (PCI) P2Y12 receptor (P2Y12r) inhibition should be achieved as soon as possible.
- Conditions
- Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome, Hypothermia, Induced
- Trial name
- NCT03273075
- Testing
- Cangrelor, Prasugrel, Ticagrelor
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Myocardial Ischemia, Acute Coronary Syndrome
EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)
The purpose of this study is to see if early INTEGRILIN® (eptifibatide) therapy in patients with non-ST-segment elevation acute coronary syndrome (ACS) reduces the occurence of death, heart attack and urgent cardiac intervention…
- Trial name
- NCT00089895
- Testing
- Eptifibatide (Integrilin)
- Volunteers
- 9,406 people
- Sponsor
- Organon and Co
Acute Coronary Syndrome, Helicobacter Pylori Infection
The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients
Patients with acute coronary syndrome (ACS) after Percutaneous Coronary Intervention (PCI) require routine treatment with dual antiplatelet (DAPT) treatment, but with the high risk of bleeding, gastrointestinal bleeding is the…
- Trial name
- NCT04728516
- Testing
- Vonoprazan-based dual eradication therapy for two weeks, amoxicillin, Pantoprazole
- Where
- 42 sites in China
- Volunteers
- 2,600 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Myocardial Infarction (AMI), Chest Pain
One-hoUr Troponin Using a High-sensitivity Point-Of-Care Assay in Emergency Primary Care
Acute chest pain is a prevalent medical emergency in primary emergency care settings. Triage of chest pain prior to hospital admission presents significant challenges due to the absence of sufficiently sensitive diagnostic tools.
- Conditions
- Acute Myocardial Infarction (AMI), Chest Pain, Acute Coronary Syndromes (ACS), Non-cardiac Chest Pain
- Trial name
- OUT-POC (NCT06853626)
- Testing
- QuidelOrthos TriageTrue hs-cTnI whole-blood assay
- Where
- 6 sites in Norway
- Volunteers
- 2,500 people
- Sponsor
- University of Oslo
Stable Angina, Unstable Angina
Safety and Effectiveness Evaluation of COBRA PzF Coronary Stent System: A Post Marketing Observational Registry
A multi-center, prospective, consecutive enrolled, observational registry. The population being studied includes all patients undergoing treatment of "de novo" lesions in native coronary vessels, saphenous vein graft and/or…
- Conditions
- Stable Angina, Unstable Angina, ACS - Acute Coronary Syndrome, STEMI
- Trial name
- eCOBRA (NCT03103620)
- Testing
- COBRA PzF Coronary Stent System
- Where
- 18 sites in France
- Volunteers
- 1,027 people
- Sponsor
- CeloNova BioSciences, Inc.
Acute Coronary Syndromes
Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors With Statin for ACS Patients
Cardiovascular diseases (CVDs) remain the leading cause of death globally, with a dominant contribution from atherosclerotic CVD (ASCVD).
- Trial name
- NCT07736313
- Testing
- PCSK9 inhibitor plus rosuvastatin 20 mg tab, Rosuvastatin 20 Mg Oral Tablet
- Volunteers
- 120 people
- Sponsor
- Assiut University