Clinical trials: ACT
Malaria
Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria
The purpose of this study is to compare the efficacy and safety of the fixed combination of pyronaridine artesunate (Pyramax®, PA) (180:60 mg) with that of standard chloroquine therapy in children and adults with acute…
- Trial name
- NCT00440999
- Testing
- Pyronaridine artesunate, Chloroquine
- Where
- 5 sites in Cambodia, India and 2 more
- Volunteers
- 456 people
- Sponsor
- Medicines for Malaria Venture
Anxiety, Depression
The Effectiveness of Acceptance and Commitment Therapy (ACT) on Dysfunctional Attitudes and Difficulties in Emotion Regulation Among University Students in Malaysia
The goal of this clinical trial is to learn if Acceptance and Commitment Therapy (ACT) can reduce dysfunctional attitudes and difficulties in emotion regulation among university students in Malaysia.The main questions it aims to…
- Conditions
- Anxiety, Depression, Stress
- Trial name
- NCT07256093
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- Universiti Sains Malaysia
Alcohol Use Disorder
Effectiveness of Internet-Based Self-Help ACT With Behavioral Activation in Improving Alcohol Use Abstinence Among Ethnic Minority Young Adults With Alcohol Use Disorder
The goal of this clinical trial is to examine the preliminary effectiveness and feasibility of internet-based self-help acceptance and commitment therapy with behavioral activation for ethnic minority young adults with alcohol…
- Trial name
- NCT06779006
- Testing
- Self-help acceptance and commitment therapy with behavioral activation
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Eye Manifestations
Comparison of Ectoin® Containing Eye Drops and Ectoin® Containing Eye Spray With the Eye Spray Tears Again®
This study aims to gain knowledge on the duration of symptom relief of environmental disorders of the eye as might be present in allergy sufferers after allergen exposure following application of the study products.
- Trial name
- NCT04021225
- Testing
- Ectoin® Allergy Eye Drops 2%, Ectoin® Eye Spray Colloidal, Tears Again® eye spray
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Bitop AG
Shame, Stigma, Social
Feasibility Trial of an Acceptance and Commitment Therapy Intervention for Individuals Experiencing Homelessness
The current project's overall aim is to develop and evaluate the feasibility and preliminary efficacy of an ACT intervention to promote psychological well-being and mitigate the deleterious effects of shame and self-stigma in…
- Conditions
- Shame, Stigma, Social, Well-Being
- Trial name
- NCT04243018
- Testing
- Acceptance and Commitment Therapy Group Treatment, Peer Support Group
- Where
- 3 sites in Ireland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Problem Gambling
Brief ACT Intervention for Problem Gambling: A Pilot Study
The goal of this pilot study is to learn if Acceptance and Commitment Therapy (ACT) works to treat Problem Gambling in young adults.The main questions it aims to answer are: Does ACT therapy improve health and gambling behavior?…
- Trial name
- NCT07066488
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Universidad Europea de Madrid
Fear of Cancer Recurrence, Cancer Survivorship
Acceptance and Commitment Therapy (ACT) Versus Cognitive Behavioural Therapy (CBT) for Fear of Cancer Recurrence (FCR) in Cancer Survivors and Their Spouses
Fear of cancer recurrence (FCR) is one of the most significant psychological burdens faced by cancer survivors. FCR describes the fear, worry, or concern relating to the possibility that cancer will come back or progress, and is…
- Trial name
- CARE-Pilot (NCT07749560)
- Testing
- ACT couple intervention, CBT couple intervention
- Volunteers
- 128 people
- Sponsor
- University Center of Tumor Diseases, Frankfurt University Hospital
Carcinoma, Adrenal Cortical
Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)
The purpose of this study is to determine whether treatment with etoposide, doxorubicin, cisplatin and mitotane (EDP/M) prolongs survival as compared to streptozotocin and mitotane (Sz/M) in patients with advanced adrenocortical…
- Trial name
- NCT00094497
- Testing
- Etoposide, Doxorubicin, Cisplatin
- Where
- 32 sites in United States, Australia and 6 more
- Volunteers
- 304 people
- Sponsor
- Collaborative Group for Adrenocortical Carcinoma Treatment
Major Depressive Disorder
Storytelling Video Intervention for Depressed Primary Care Patients - Open Trial
The overall aim of this program of research is to develop a collaborative narrative intervention for patients with depression being treated in primary care.
- Trial name
- sTVi-Open (NCT02309060)
- Testing
- Storytelling Video Intervention (sTVi)
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Butler Hospital
Chronic Pain
Internet-delivered ACT for Chronic Pain
The overall aim of the present study is to evaluate an internet-delivered Acceptance and Commitment therapy treatment (iACT) for patients with chronic pain.
- Trial name
- iACT (NCT03105908)
- Testing
- Internet delivered Acceptance and Commitment therapy, Waiting list control condition
- Where
- Sweden
- Volunteers
- 113 people
- Sponsor
- Rikard Wicksell
Alzheimer Disease, Smell Loss
Olfactory Biopsies
This research study aims to investigate the function of the olfactory lining in the nasal cavity and its potential alterations in both healthy and diseased conditions. The olfactory lining is involved in the sense of smell.
- Conditions
- Alzheimer Disease, Smell Loss, Smell Dysfunction
- Trial name
- NCT07021040
- Testing
- olfactory testing, Odor stimulation, Olfactory biopsy
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Duke University
Caregiver Burden
Comparison of ACT and CBSM for Caregivers in Cancer
The goal of this clinical trial is to compare the effectiveness of cognitive-behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the fear of recurrence, quality of life, psychological distress, and…
- Trial name
- NCT07329868
- Testing
- Cognitive Behavioral Stress Management (CBSM), Acceptance and Commitment Therapy (ACT)
- Where
- Iran
- Volunteers
- 66 people
- Sponsor
- Ardakan University
Psychotic Disorders, Acceptance and Commitment Therapy
Inpatient Group Acceptance and Commitment Therapy (ACT) for Psychosis Spectrum Disorder
The pilot study that will serve as the basis for the larger project - a multicenter randomized controlled single-blinded trial (RCT) will focus on testing the feasibility and efficacy of an inpatient group ACT treatment program…
- Conditions
- Psychotic Disorders, Acceptance and Commitment Therapy, Psychotherapy, Group, Inpatients
- Trial name
- ASPIRE (NCT06086184)
- Testing
- ACT group therapy
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Vivantes Netzwerk für Gesundheit GmbH
Rudeness/Incivility, Aggression or Violence Against Healthcare Workers in an Ophthalmic Emergencies Unit.
Antisocial Behavior on Healthcare Professionals in an Emergency Unit.
At the hospital, the attacks against health professionals are becoming commonplace, making working conditions difficult. The ophthalmological emergencies are a perfect testing ground to evaluate the effectiveness of a series of…
- Trial name
- PREVURGO (NCT02015884)
- Where
- France
- Volunteers
- 58,465 people
- Sponsor
- Hospices Civils de Lyon
Atrial Fibrillation
Arterial Versus Venous Activated Clotting Time (ACT) Measurements During Atrial Fibrillation Ablations
Activated clotting times (ACTs) are routinely measured throughout atrial fibrillation ablations to monitor anticoagulation prior to and after heparin administration.
- Trial name
- NCT04285840
- Testing
- Venous ACT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Non-cystic Fibrosis Bronchiectasis, Chronic Mucus Hypersecretion
Simeox Therapy at Home Versus Standard of Care in NCFB Patients With CMH
This pilot RCT will assess benefits of Simeox technology on lung function, respiratory symptoms, health-related quality of life, subjective efficiency, device adherence at home, Patient satisfaction, tolerance, safety, and…
- Trial name
- NCT06237348
- Testing
- Simeox, Control
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Physio-Assist
Healthy Participants Study
ACT-based EMI in College Students
This study aims to evaluate the acceptability and effectiveness of a transdiagnostic, Acceptance and Commitment Therapy (ACT)-based ecological momentary intervention (EMI) among college students.
- Trial name
- NCT06843395
- Testing
- ACT-based ecological momentary intervention, Mood monitoring
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Psychological Distress
Guided Eight-week Online Acceptance and Commitment Therapy for Distressed Family Caregivers of People With Dementia
The pilot randomized controlled trial aims to assess effects of a guided online acceptance and commitment therapy (ACT) intervention on distressed family caregivers of people with dementia (PwD) compared to the control group.
- Trial name
- NCT04847986
- Testing
- acceptance and commitment therapy (ACT), Control group
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Alabama at Birmingham
Smoking Cessation
Individual Acceptance and Commitment Therapy (ACT) for Smoking Cessation for Schizophrenic Patients
The purpose of this study is to evaluate the efficacy of using Acceptance and commitment therapy for smoking cessation for schizophrenic patients.
- Trial name
- NCT03253445
- Testing
- Acceptance and commitment therapy, Control
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Malaria, Falciparum
Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers
The aim of such a study is to evaluate the impact of a therapeutic dose of Eurartesim™ compared to Riamet®, after multiple dose administration for 3 days in healthy male and female subjects on electrocardiographic parameters.
- Trial name
- NCT01103830
- Testing
- Eurartesim™, Riamet®
- Where
- France
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- sigma-tau i.f.r. S.p.A.