Clinical trials: ADHF
Acute Decompensated Heart Failure
Reprieve System Pilot Study
The objective of the study is to evaluate the use of the Reprieve System to decongest subjects with acute decompensated heart failure.
- Trial name
- NCT06272734
- Testing
- Reprieve System
- Where
- Georgia
- Volunteers
- 50 people
- Sponsor
- Reprieve Cardiovascular, Inc
Heart Failure, Congestive, Heart Decompensation
Longitudinal Registry for Advanced Heart Failure Patients
The purpose of this study is to gather information to better understand the characteristics, medical management techniques and outcomes of patients with chronic severe Heart Failure (HF).
- Trial name
- NCT00364416
- Testing
- Any treatment used to treat CHF
- Volunteers
- 1,466 people
- Sponsor
- Scios, Inc.
Acute Decompensated Heart Failure
Does Ultrasound Assessment for Extravascular Lung Water and IVC Measurement Affect Outcomes in Inpatient Heart Failure Management?
This study evaluates daily POCUS/FCU exams on patients admitted for acute decompensated heart failure with primary end point of acute kidney injury while in hospital.
- Trial name
- NCT04436718
- Testing
- Daily pocus exam
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Riverside University Health System Medical Center
Heart Failure
The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure
Evidence showed that glucocorticoids could induce potent diuretic actions and improve renal functions in patients with decompensated congestive heart failure.
- Trial name
- NCT00953303
- Testing
- glucocorticoid, standard care
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Hebei Medical University
CHF, ADHF
Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)
The purpose of this study is to determine the relationship between the levels of Ribonucleic acid (RNA) circulating molecules, including ones in extracellular vesicles from different organs in the blood and in the saliva of…
- Conditions
- CHF, ADHF, Control
- Trial name
- SEAL-HF (NCT06169540)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Heart Failure, Acute Heart Failure
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.
- Trial name
- REDEFINE-HF (NCT06008197)
- Testing
- Finerenone
- Where
- 356 sites in United States, Argentina and 24 more
- Volunteers
- 5,200 people
- Sponsor
- Colorado Prevention Center
Acute Heart Failure
Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure.
Intravenous (IV) loop diuretics have been a key component in treating pulmonary edema since the 1960s and has a Class 1 recommendation in the 2021 guidelines for acute heart failure.
- Trial name
- NCT06024889
- Testing
- Furosemide Injection
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Johannes Grand