Clinical trials: AFib
Atrial Fibrillation
The Validation of the FibriCheck Application for the Detection of Atrial Fibrillation
Optical sensing technologies have the potential to enable long-term heart rhythm monitoring. The medically certified and clinically validated FibriCheck technology has proven its value for spot-check measurements to detect AF.
- Trial name
- FLASH-AF (NCT03620656)
- Testing
- FibriCheck
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Qompium NV
Persistent Atrial Fibrillation
A Study on the Therapeutic Value of Additional Left Atrial Posterior Wall Isolation Guided by Voltage Mapping in Persistent Atrial Fibrillation.
This prospective, multicenter, randomized controlled study was designed to investigate the feasibility, efficacy and safety of pulsed field ablation (PFA) strategies for persistent atrial fibrillation.
- Trial name
- NCT07590661
- Testing
- superior vena cava isolation, Abnormal left atrial substrate
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Hangzhou Dinova EP Technology Co., Ltd
Atrial Fibrillation, Arrhythmias, Cardiac
Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias
The Apple Heart Study (AHS) is a research study conducted to evaluate whether the Apple Heart Study App can use data collected on the Apple Watch to identify irregular heart rhythms, including those from potentially serious heart…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
- Trial name
- NCT03335800
- Testing
- Apple Heart Study App
- Where
- United States
- Volunteers
- 419,927 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Atrial Fibrillation, Atrial Flutter
HeartBeam ECG Registry
The HeartBeam ECG Registry will collect ECG recordings acquired with the HeartBeam System with relevant clinical information in clinical settings.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Bradycardia, Tachycardia
- Trial name
- NCT07501299
- Testing
- Electrocardiogram (ECG)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- HeartBeam, Inc.
Stroke, Hypertension
DELPHI in Subjects at Risk for Stroke and Dementia
The DELPhi system is a software device that is used for the noninvasive evaluation of brain plasticity and connectivity. The DELPhi software uses EEG and TMS devices as accessories.
- Conditions
- Stroke, Hypertension, Diabete Mellitus, Dyslipidemias
- Trial name
- NCT03884647
- Testing
- DELPhI system
- Where
- 4 sites in United States, Israel
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Atrial Fibrillation
The LIVMOR Data Collection Study for the Development and Validation of L-1000AF System
The LIVMOR Data Collection Study is a multicenter, IDE Exempt Study to generate a library of device-specific signals collected noninvasively.
- Trial name
- NCT04104191
- Testing
- L-1000AF System
- Where
- 2 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- LIVMOR, Inc.
Healthy
Clinical Performance of Masimo INVSENSOR00057 for Atrial Fibrillation Detection
This study is designed to validate the performance of Masimo INVSENSOR00057 in detecting atrial fibrillation. The noninvasive ECG measurements will be compared to results obtained from an FDA-cleared ECG monitor.
- Trial name
- NCT05476250
- Testing
- INVSENSOR00057
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Atrial Fibrillation, Afib
Further Study of AFGen1 Clinical Performance
AFGen1 is indicated for use on symptomatic or asymptomatic adults who are at risk of developing or who have atrial fibrillation, where a software assisted analysis of ambulatory ECG is needed to identify episodes of Afib.
- Conditions
- Atrial Fibrillation, Afib, ECG
- Trial name
- CS3 (NCT06335498)
- Testing
- ECG co-measurement, Periodic ECG triggered measurement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TriVirum, Inc.
Non-valvular Atrial Fibrillation (NVAF)
To Compare the Pharmacokinetics and Safety After a Single Dose Administration of IN-G00002 and IN-R00002 in Healthy Adult Volunteers
To compare the pharmacokinetics and safety after a single dose administration of IN-G00002 and IN-R00002 in healthy adult volunteers
- Trial name
- NCT06725355
- Testing
- IN-R00002, IN-G00002
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Arrhythmias, Cardiac, Atrial Fibrillation
Screening of Cardiac Arrhythmias With Wrist-worn Aino ECG Cardiac Monitor
The study investigates the performance pf PulseOn Arrhythmia Monitor System that includes a wrist-worn device, which combines continuous optical heartbeat interval monitoring and intermittent ECG measurement, and a data…
- Trial name
- NCT05196412
- Testing
- PulseOn Arrhythmia Monitor device
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- PulseOn Oy
Atrial Fibrillation
Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103
This study is an evaluation of the safety and tolerability of XEN-D0103 in healthy subjects. Part 1 assesses the safety, tolerability and blood levels of the ascending single doses of XEN-D0103.
- Trial name
- NCT02390258
- Testing
- 10mg XEN-D0103, 30mg XEN-D0103, 60mg XEN-D0103
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Xention Ltd
Atrial Fibrillation
Effect of Diltiazem on Pharmacokinetics of BMS-914392
The purpose of this study is to assess the effects of diltiazem on the pharmacokinetics of single-dose BMS-914392 in healthy subjects.
- Trial name
- NCT01211808
- Testing
- BMS-914832, Diltiazem
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Atrial Fibrillation
Evaluation of Blood Pressure Monitor With AFib Screening Feature
This study aims to evaluate the safety and effectiveness of the Omron blood pressure (BP) monitor with AFib screening feature. The primary outcome is to validate if the Omron BP-monitor with AFib screening feature meets…
- Trial name
- NCT05599308
- Testing
- OMRON blood pressure monitor with AFib screening feature, Microlife WatchBP Home A
- Where
- 5 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Omron Healthcare Co., Ltd.
Healthy, Atrial Fibrillation
Validation of the Performance of the Electrocardiogram (ECG) Function in the Masimo INVSENSOR00057
The objective of this study is to validate the performance of the electrocardiogram (ECG) function of the Masimo INVSENSOR00057 against contemporaneous measurements
- Trial name
- NCT06071754
- Testing
- Masimo INVSENSOR00057
- Where
- 4 sites in United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Non-valvular Atrial Fibrillation
Observe the Safety and Effectiveness of the WATCHMAN FLX™ for Subjects in Hong Kong
The primary objective of this study is to observe the safety and effectiveness of the WATCHMAN FLX™ Left Atrial Appendage Closure (LAAC) Device for subjects with non-valvular atrial fibrillation to reduce the risk of stroke in…
- Trial name
- NCT04096963
- Testing
- The WATCHMAN FLX Delivery System
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation, Syncope
LUX-Dx Insertable Cardiac Monitor Remote Programming and Performance Study
The LUX-Dx PERFORM Study had two primary objects which were (1) to characterize, in a general patient population, the utilization of the remote programming feature of the Boston Scientific (BSC) Insertable Cardiac Monitor (ICM)…
- Conditions
- Atrial Fibrillation, Syncope, Cryptogenic Stroke
- Trial name
- LUX-Dx PERFORM (NCT04732728)
- Where
- 24 sites in United States
- Volunteers
- 727 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Detection of Heart Rhythm and BP With RhythmPadBP
This study will assess a new device, the RhythmPadBP, which detects heart rhythm and measure blood pressure simply by placing palms of the hands on a pad containing titanium electrodes.
- Trial name
- SLAF-BP (NCT03813446)
- Testing
- Device: RhythmPadBP
- Where
- United Kingdom
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Cardiocity Limited
Atrial Fibrillation
Electrocardiogram Clinical Validation Study
The purpose of the study is to confirm the Garmin ECG (electrocardiogram) software algorithm can detect and classify atrial fibrillation and normal sinus rhythm on single lead ECG data derived from a Garmin wrist-worn, consumer…
- Trial name
- NCT04842123
- Testing
- Electrocardiogram
- Where
- 6 sites in United States
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Garmin International
Atrial Fibrillation
Validation Study of Frontier X Plus (FX+) Device
The main objective of this study is to validate the specificity and sensitivity of FX+ detecting atrial fibrillation (AF) in both AF and non-AF subjects using a comparative approach, which involves using both a US FDA-cleared…
- Trial name
- NCT06471764
- Testing
- FX+ and 12-Lead ECG Recording
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Fourth Frontier Technologies Pvt Ltd.