Clinical trials: AIDS-Related Opportunistic Infections, open to volunteers
HIV, AIDS
Efficacy and Safety of Immune Checkpoint Inhibitors for Refractory Opportunistic Infections in AIDS
This prospective, single-arm, open-label study aims to evaluate the efficacy and safety of a PD-1 inhibitor (Sintilimab) combined with standard anti-infective therapy in patients with advanced HIV disease (AHD) who are suffering…
- Conditions
- HIV, AIDS, Immune Checkpoint Inhibitors, Refractory Opportunistic Infection
- Trial name
- NCT07579247
- Testing
- Sintilimab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Public Health Clinical Center
Opportunistic Infections, HIV Related, Disseminated Mycobacterium Avium Complex Infection
Enhanced Treatment Strategy for Disseminated MAC Infection in HIV Patients: A Randomized Controlled Trial
Background: Disseminated Mycobacterium avium complex (MAC) infection remains a serious opportunistic infection in patients with advanced HIV infection, particularly among those with severe immunosuppression.
- Trial name
- NCT07585461
- Testing
- Standard Triple Therapy, Experimental: Standard Triple Therapy Plus Fluoroquinolone
- Volunteers
- 124 people
- Sponsor
- Shanghai Public Health Clinical Center
Opportunistic Infections, HIV Related
Real-world Cohort Study of Antiretroviral Therapy in HIV Patients With Opportunistic Infections
This study stratified and compared the differences in virological efficacy and sustained viral suppression status between HIV-infected patients with and without opportunistic infections, providing a basis for optimizing…
- Trial name
- NCT07526363
- Volunteers
- 8,000 people
- Sponsor
- Shanghai Public Health Clinical Center