Clinical trials: ALLOGRAFT
Bone Volume, Immediate Implant With Bone Graft
Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars
Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients.
- Trial name
- NCT06962878
- Testing
- Xenograft, Allograft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
B-cell Chronic Lymphocytic Leukemia, Nodal Marginal Zone B-cell Lymphoma
Yttrium Y 90 Ibritumomab Tiuxetan, Fludarabine, Radiation Therapy, and Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Monoclonal antibodies, such as yttrium Y 90 ibritumomab tiuxetan, can block find cancer cells and either kill them or carry cancer-killing substances to them without harming normal cells.
- Conditions
- B-cell Chronic Lymphocytic Leukemia, Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma
- Trial name
- NCT00119392
- Testing
- rituximab, cyclosporine, fludarabine phosphate
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Fred Hutchinson Cancer Center
Nonterminal Premolar Needing Extraction
OsteoGen Plug vs. Freeze-dried Bone Allograft With Collagen Barrier
The study will be a multi-site, randomized, two-arm, controlled clinical trial using OsteoGen® Plug (Test) vs Freeze-dried Bone Allograft with collagen barrier (Control) for alveolar ridge preservation (ARP) in posterior…
- Trial name
- NCT06447844
- Testing
- OsteoGen Plug, BioGide
- Where
- 9 sites in United States
- Volunteers
- 70 people
- Sponsor
- McGuire Institute
Prostate Cancer
Miami Membrane for Potency (MMEP) Trial
The use of dehydrated human amnionic membrane allograft improves erectile function recovery (as measured by (Sexual History Inventory for Men (SHIM) score) at 12 months after robotic assisted radical prostatectomy (RARP) compared…
- Trial name
- MMEP (NCT02710422)
- Testing
- Amniotic Membrane Placement, EPIC 26, PSA Measurement
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Miami
Bronchiolitis Obliterans
Immune Mechanisms of Rejection in Human Lung Allografts
The investigators have obtained compelling evidence that the development of anti-human leukocyte antigen (anti-HLA) antibodies against mismatched donor antigens significantly correlates with the development of bronchiolitis…
- Trial name
- NCT00861900
- Volunteers
- 778 people
- Sponsor
- Washington University School of Medicine
Dexmedetomidine, Liver Transplantation, Allograft Function, Survival
Dexmedetomidine and Liver Transplantation
1.1. Background 1.1.1. Perioperative ischaemia/reperfusion (I/R) injury during liver transplantation is strongly associated with early allograft dysfunction, graft loss, and mortality. 1.1.2.
- Trial name
- NCT03770130
- Testing
- Dexmedetomidine, Saline
- Where
- China
- Volunteers
- 330 people
- Sponsor
- RenJi Hospital
Graft Rejection, Kidney Transplantation
TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Response to Extracorporeal Photo-aphereSiS
With this project, the research team aims to identify the molecular pathways associated with the response to extracorporeal photonchemioapheresis (ECP) in kidney or lung transplant patients suffering from chronic rejection, by…
- Conditions
- Graft Rejection, Kidney Transplantation, Lung Transplantation, Antibody-Mediated Rejection
- Trial name
- TRACKLESS (NCT07316829)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Keloid Scar
Pilot Study to Evaluate Clinical Outcomes With the Use of Biovance Following Keloid Scar Revision Surgery
The main purpose of this study is to see if there is clinical benefit of using Biovance in reduction of the recurrence of keloids when used to revise them. It will also assess the postoperative complications.
- Trial name
- NCT02521402
- Testing
- Biovance
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Golla Center for Plastic Surgery
Alveolar Ridge Augmentation, Bone Transplantation
Peri-Implant Soft and Hard Tissue Stability Following Socket Preservation
The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature.
- Trial name
- NCT05005377
- Testing
- Socket Preservation with Platelet-Rich Fibrin, Socket Preservation with Freeze-Dried Bone Allograft
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Psychiatric Diagnosis, Cognition Disorders
Mood and Cognitive Outcome After Heart Transplantation (the MOODHEART Study)
The investigators aim at characterizing neuropsychiatric consequences of heart transplantation (HTX) and at assessing the impact of depressive symptoms after HTX on mortality and cardiac allograft vasculopathy (CAV).
- Trial name
- NCT02035865
- Where
- Norway
- Volunteers
- 74 people
- Sponsor
- Oslo University Hospital
Liver Damage
Hypothermic Machine Preservation-Phase 2
This is a study comparing a technique of continuous circulation to the liver as a means of preventing liver damage during transportation to the transplant hospital.
- Trial name
- HMP2 (NCT01274520)
- Testing
- The Medtronic Portable Bypass System (PBS®)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Columbia University
Kidney Transplant Rejection, Kidney Transplant; Complications
Australian Genomics Of Chronic Allograft Dysfunction Study
The goal of the Australian Genomics of Chronic Allograft Dysfunction (AUSCAD) study is a single centre (Westmead Hospital), prospective, observational study, which enrols patients at time of kidney (or kidney-transplant)…
- Trial name
- AUSCAD (NCT06314230)
- Where
- 2 sites in Australia
- Volunteers
- 500 people
- Sponsor
- Western Sydney Local Health District
Kidney Failure, Chronic
Mineralocorticoid Receptor Antagonist and Kidney Allograft Histology
Chronic allograft nephropathy is one of dominant causes of long term kidney transplant failure. Its main histological determinant is interstitial fibrosis and tubular atrophy.
- Trial name
- NCT01510795
- Testing
- spironolactone
- Volunteers
- 40 people
- Sponsor
- Clinical Hospital Merkur
Lymphoma, Disorder Related to Bone Marrow Transplantation
Allogeneic Transplantation in Patients With Cutaneous T-Cell Lymphoma
The goal of this clinical research study is to see if receiving a transplant of blood stem cells (cells that can produce blood) or bone marrow from either a related donor (brother, sister or other relative) or an unrelated…
- Trial name
- NCT00506129
- Testing
- Fludarabine, Melphalan, Allogeneic Transplant
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Tooth Loss
Ridge Preservation With Putty Allografts
The study will consist of randomized controlled clinical study trial comparing the results of a demineralized putty allorgraft versus a combined mineralized/demineralized putty allograft in approximately 30 patients, 15 per…
- Trial name
- NCT03956251
- Testing
- Combined Mineralized/Demineralized Putty Allograft, Demineralized Putty Allograft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pulp Disease, Dental
Evaluation of Different Materials in Pulpotomy of Primary Molars
The aim of the current study is to evaluate and compare clinical and radiographic success and antibacterial effect of Hyaluronic Acid and Amniotic membrane pulpotomy in primary molars in comparison with MTA pulpotomy (Randomized…
- Trial name
- NCT05981352
- Testing
- mineral trioxide aggregate pulpotomy, Dehydrated amniotic membrane pulpotomy, Hyaluronic acid pulpotomy
- Volunteers
- 36 people
- Sponsor
- Ain Shams University
Blood Stem Cell Transplant Failure, Leukemia
Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide
The goal of this clinical research study is to learn about the safety of giving a stem cell transplant from a tissue-mismatched donor, followed by cyclophosphamide, to patients with certain types of blood disorders or blood…
- Conditions
- Blood Stem Cell Transplant Failure, Leukemia, Hematologic Malignancies
- Trial name
- NCT01010217
- Testing
- Cyclophosphamide, Fludarabine, Melphalan
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- M.D. Anderson Cancer Center
Bone Neoplasm
Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute
This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone defects following surgical…
- Trial name
- BAGvsTCP (NCT00841152)
- Testing
- Bioactive glass, Beta-tricalcium phosphate (ChronOs), Autograft
- Where
- 5 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Acute Myeloid Leukemia
Feasibility and Efficiency Study of Leukemic Cell Mobilization With Plerixafor Injection
The study will be conducted as a single center Phase I/II study to evaluate the safety of administering Plerixafor administered as part of a myeloablative preparative regimen (Institutional Protocol:Fludarabine 50mg/m2/da x 4…
- Trial name
- NCT01141543
- Testing
- Plerixafor (mozobil)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Allograft
Study of Drug Acceptance and Its Persistence Over Time in Patients Receiving a Haematopoietic Stem Cell Allograft
Allograft patients have a complex care pathway and are left with a large number of prescribed medications. They have to deal with changes linked to the transplant (change in taste, fatigue, regular monitoring, risk of GVH (graft…
- Trial name
- AdHemLim (NCT05164835)
- Testing
- pharmaceutical follow-up
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Limoges
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