Clinical trials: ANS Function
Generalized Anxiety Disorder
The Effects of Emotional Exposure on State Anxiety
A randomized repeated-measures crossover clinical trial was performed. Forty healthy, female college students completed a 30 min session of YogaFit and a time-matched seated rest condition on separate days.
- Trial name
- NCT03458702
- Testing
- YogaFit, Quiet Rest
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Stroke
Tai Chi Training in Stroke Survivors
People with stroke suffer from different impairments, including the ability to dual-tasking, increased arterial stiffness, and dysfunction of the autonomic nervous system.
- Trial name
- NCT03252236
- Testing
- Tai Chi, Conventional exercise
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The Hong Kong Polytechnic University
Reflex Sympathetic Dystrophy
Investigation of the Efficacy of tDCS in the Treatment of Complex Regional Pain Syndrome (CRPS) Type 1
The efficacy of the current standard non-pharmacological treatments for complex regional pain syndrome (CRPS), a painful syndrome mostly occurring after musculoskeletal trauma, is suboptimal.
- Trial name
- NCT01960400
- Testing
- Graded motor imagery (GMI)
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Université de Sherbrooke
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function
Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.
Spinal anaesthesia has the advantage that produced nerve block by the injection of local anaesthetic into cerebrospinal fluid (CSF).
- Trial name
- NCT04275375
- Testing
- observation study about the autonomic response after spinal anesthesia
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- National Central University
Autonomic Nervous System (ANS) Functioning and Mood State
Effects of Barefoot Running vs. in Shoes on Physiology and Mood
Aerobic exercise impacts bodily processes implicated in the pathophysiology of major depression. Consistent with these effects, aerobic exercise in general, and running in particular, has been repeatedly shown to have both…
- Trial name
- NCT01733381
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Complex Regional Pain Syndrome, Type I
Pain Exposure Physical Therapy (PEPT) Versus CBO in Patients With Complex Regional Pain Syndrome Type I (CRPS-1)
The current Dutch CBO guideline treatment of Complex Regional Pain Syndrome Type I (CRPS-1) is very disappointing with chronification, disability and subsequent high medical costs and personal suffering.
- Trial name
- PEPTOC (NCT00817128)
- Testing
- PEPT, CBO standard
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Radboud University Medical Center
Type 2 Diabetes, Diabetes Mellitus, Type 2
Heart Rate Variability-Guided Exercise Training in Type 2 Diabetes
The primary aim of this randomized clinical trial is to determine the effectiveness of a 16 wk individualized aerobic exercise program, using heart rate variability to guide the exercise prescription, for increasing aerobic…
- Conditions
- Type 2 Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus in Obese
- Trial name
- NCT04910997
- Testing
- Aerobic exercise training
- Where
- United States
- Sponsor
- University of Illinois Chicago
Spinal Cord Injuries
Task-specific Epidural Stimulation Study
The investigators propose to understand the role of lumbosacral spinal cord epidural stimulation (scES) in recovery of autonomic nervous system function, voluntary movement, and standing in individuals with severe spinal cord…
- Trial name
- TSEPI (NCT03364660)
- Testing
- Acute epidural stimulation for cardiovascular stability, Long Term Epidural Stimulation for Cardiovascular Stability, Participants undergo approximately 4 months of epidural stimulation for voluntary movement.
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Spinal Cord Injuries (SCI), Spinal Cord Injury
Transcutaneous Spinal Electrical Stimulation to Improve Exercise Function After Spinal Cord Injury.
Our overall objective is to decrease the prevalence of multiple sedentary-related diseases that are secondary consequences of spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Spinal Injury
- Trial name
- NCT07692191
- Testing
- Transcutaneous spinal electrical stimulation (TSES)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Primary Headaches (Migraines, Tension, Cluster Headaches)
Osteopathic Manual Therapy (OMT) and Brain Structure and Function in Primary Headache Patients: A Pilot Study
Chronic headaches are associated with changes in brain structure and function that may be associated with increased suffering and disability.
- Trial name
- NCT06841627
- Testing
- Osteopathic Manipulative Therapy
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Immune System Processes, Inflammatory Activation and Modulation
The Compassion and Attention Longitudinal Meditation Study
The increasingly widespread use of meditation for stress-related emotional and medical conditions highlights the urgent need to rigorously evaluate mechanisms through which the benefits of practice might be conferred.
- Conditions
- Immune System Processes, Inflammatory Activation and Modulation, ANS Function
- Trial name
- CALM (NCT01251341)
- Testing
- Cognitive-Based Compassion Training, Mindful Attention Training, Adult Health Education Curriculum
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Resistant Hypertension, Medication Adherence
Heart Rate Variability and Medication Adherence in Resistant Hypertension
This single-center, cross-sectional observational study examines the relationship between adherence to antihypertensive therapy - verified objectively by therapeutic drug monitoring (TDM) - and heart rate variability (HRV) in…
- Conditions
- Resistant Hypertension, Medication Adherence, Autonomic Nervous System
- Trial name
- HRV-HYP-1 (NCT07707583)
- Testing
- Heart rate variability recording (Polar H10) ·, Therapeutic drug monitoring (antihypertensive drug levels), Questionnaires (MARS-CZ, PHQ-9, SF-36, IPAQ)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Peripheral Diabetic Neuropathy, Cardiovascular Autonomic Neuropathy
The Association Between Cognitive Function and Neuropathy in Individuals With Type 2 Diabetes
The goal of this observational study is to evaluate whether individuals with different types of diabetic neuropathy (peripheral and cardiovascular autonomic neuropathy) are at an increased risk of cognitive impairment and to…
- Conditions
- Peripheral Diabetic Neuropathy, Cardiovascular Autonomic Neuropathy, Cognitive Impairment, Diabetes Type 2
- Trial name
- ASCEND (NCT06857994)
- Where
- Denmark
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Traumatic Brain Injury
Effects of Intranasal Nerve Growth Factor for Traumatic Brain Injury
Traumatic bain injury(TBI) remains a hidden epidemic involving individuals affected predominantly at a young age who in the most severe cases remain with permanent physical,psychological and cognitive deficits.This study will…
- Trial name
- NCT01212679
- Testing
- nerve growth factor, nomral saline
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Jinling Hospital, China
Stroke, Vagus Nerve Stimulation
Vagal Stimulation in Individuals With Stroke
The aim of this study is to investigate the effects of manual vagus nerve stimulation (VNS) on motor, autonomic, and cognitive functions in individuals with chronic stroke.
- Conditions
- Stroke, Vagus Nerve Stimulation, Motor Function, Otonomic Function
- Trial name
- NCT07822854
- Testing
- vagus nerve stimulation, classic rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Nermin KART
COVID-19
An Observational Study of Neurologic Function After COVID-19 Infection
Background: COVID-19 is an infection caused by a coronavirus. It can affect different parts of the body. For most people, it causes fevers or trouble breathing. Some people can have symptoms long after they recover.
- Trial name
- NCT04564287
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Atrial Fibrillation Recurrent
The Impact of Autonomic Function on Atrial Fibrillation Recurrence After Pulmonary Vein Ablation
This is a prospective and observational study. The investigator speculated that the use of DC in patients with paroxysmal AF can serve as a predictor for early and late AF recurrence following CPVI.
- Trial name
- NCT06202209
- Testing
- Circumferential Pulmonary Vein Isolation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Prediabetes, Obese
Inflammation Inhibition in Prediabetic Humans
Prediabetes, characterized by elevated fasting blood sugar or exaggerated blood sugar response to sugar ingestion, effects over 79 million adult Americans and is a precursor to the development of Type 2 diabetes.
- Trial name
- INCITE (NCT01977417)
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce
Ischemic Stroke
Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
The purpose of this study is to determine whether remote ischemic postconditioning (RIPostC) initiates autonomic nervous system response and affects the prognosis in patients with acute ischemic stroke.
- Trial name
- IRAS (NCT02777099)
- Testing
- remote ischemic postconditioning
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine