Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament (ACL) Reconstruction
Subdermal Implant-bioabsorbable Oxandrolone Pellet For Rehabilitation Following Anterior Cruciate Ligament (ACL) Surgical Reconstruction
Rehabilitation of knee stability and function after anterior cruciate ligament (ACL) reconstruction is slow and costly. The use of anabolic steroids, such as oxandrolone, may aid in the recovery of muscle mass and strength, as…
- Trial name
- IMOX (NCT06974526)
- Testing
- Oxandrolone
- Where
- 6 sites in Brazil
- Volunteers
- 96 people
- Sponsor
- Science Valley Research Institute
ACL - Anterior Cruciate Ligament Rupture
Description of Return to Sport in Amateur Athletes Who Underwent Several Functional Tests (K-STARTS, Vertical Jumps and Soleus Muscle Strength) After Initial ACL Reconstruction
ACL injuries are incapacitating for both professional and amateur athletes, with long-term repercussions on performance and return to sport (RTS). Surgical reconstruction of the ACL is the main treatment option.
- Trial name
- K-STARTS + (NCT07249645)
- Testing
- Physical tests
- Volunteers
- 230 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Injury
Maximum Oxygen Uptake in ACL-injured Professional Soccer Players
Our purpose is to evaluate maximum oxygen uptake (VO2max) in ACL-injured professional soccer players and after a six-month period of post-operative rehabilitation, compared to a control group of healthy professional soccer…
- Trial name
- NCT02674282
- Testing
- ACL reconstruction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anterior Cruciate Ligament Rupture
Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial
The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction.
- Trial name
- NCT04042688
- Testing
- intraarticular administration of tranexamic acid
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
ACL Reconstruction, Tenodesis
Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)
The anterior cruciate ligament (ACL) is one of the main stabilizers of the knee joint, and its injury is among the most common soft tissue injuries of the knee.
- Conditions
- ACL Reconstruction, Tenodesis, ACL Injuries
- Trial name
- LETOTT (NCT07049484)
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Stefano Zaffagnini
Anterior Cruciate Ligament Rupture
The Effects of Remnant-Preserving Anterior Cruciate Ligament Reconstruction on Proprioception and Functionality
Anterior cruciate ligament (ACL) reconstruction is a frequently performed surgical procedure to stabilize the knee joint biomechanically.
- Trial name
- NCT05057442
- Testing
- Proprioception assessment, functionality assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Acibadem University
Anterior Cruciate Ligament Reconstruction
A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery
The purpose of the study is to determine if there is difference in immediate postoperative pain levels (48 hours) between patients who wear a knee immobilizer splint compared to patients who do not wear a knee immobilizer splint…
- Trial name
- NCT00338663
- Testing
- knee immobilization splint
- Where
- 2 sites in Canada
- Volunteers
- 88 people
- Sponsor
- LifeMark Health Research Group
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction
Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People
Comparison of kinematic movements between patients with anterior cruciate ligament rupture and post-operative patients and normal people using a mobile dynamic X-ray device.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Healthy People
- Trial name
- NCT05619393
- Testing
- Mobilie Bi-planar X-ray Imaging system
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wang Joon Ho
Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee
Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction
The purpose of this trial is to define knee joint pathomechanics (KJPM) in the first 2 years after ACL reconstruction (ACLR) and relate these KJPM with changes in articular cartilage morphology and quality.
- Trial name
- NCT06201442
- Testing
- Imaging - magnetic resonance imaging (MRI), Blood sampling, Assessment of functionality and strength
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
ACL Injury, ACL Reconstruction
Ultrasonic Backscatter Imaging for ACL Reconstruction and Shoulder Diseases
This study explores ultrasonic scattering imaging technology in patients undergoing anterior cruciate ligament (ACL) reconstruction and those with shoulder musculoskeletal disorders.
- Trial name
- NCT06361082
- Testing
- ACL reconstruction
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Anterior Cruciate Ligament Reconstruction
interACTION: A Portable Joint Function Monitoring and Training System to Supplement Home Exercise Programs Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to ascertain if home-based therapy with monitoring via telemedicine can overcome many barriers to compliance and improve rehabilitation following ACL reconstruction.
- Trial name
- NCT02775188
- Testing
- interACTION, Standard of Care Physical Therapy
- Where
- United States
- Sponsor
- University of Pittsburgh
Adductor Canal Block
Effect of Combining Peri-hamstring Injection or Anterior Obturator Nerve Block on the Analgesic Efficacy of Adductor Canal Block for Arthroscopic Anterior Cruciate Ligament Reconstruction Under General Anesthesia
Pain after anterior cruciate ligament reconstruction with autologous hamstring graft can be attributed to both arthroscopic surgery and the graft donor site.
- Trial name
- NCT06398717
- Testing
- adductor canal block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Ruptures of the Anterior Cruciate Ligament
L-C Ligament Versus Hamstring Autograft for Primary ACL Reconstruction
The purpose of this study is to compare safety and efficacy outcomes of the L-C Ligament versus Hamstring Autograft for treatment of acute rupture of the ACL.
- Trial name
- NCT02183727
- Testing
- L-C Ligament, Hamstring Autograft
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Soft Tissue Regeneration, Inc.
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Reconstruction
Pediatric ACL: Understanding Treatment Options
Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four…
- Trial name
- PLUTO (NCT02772770)
- Testing
- Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions, Surgical technique: Transphyseal reconstruction, Surgical technique: Partial transphyseal reconstruction
- Where
- 10 sites in United States
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anterior Cruciate Ligament (ACL) Rupture, Anterior Cruciate Ligament (ACL) Reconstruction
Comparison of Video Based Phone App vs. Supervised Preoperative Exercise for ACL Reconstruction
The goal of this clinical trial is to learn if using a phone app for exercises is as effective as working with a physical therapist before anterior cruciate ligament knee surgery.
- Conditions
- Anterior Cruciate Ligament (ACL) Rupture, Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament (ACL) Injury
- Trial name
- ACL-PREHAB-APP (NCT07322497)
- Testing
- Mobile App Exercise Program, Supervised Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Bone Autograft
Anterior cruciate ligament injuries are one of the most common sports knee injuries. Their effect on the knee joint can be detrimental with patients experiencing instability and progressive damage of the intraarticular…
- Conditions
- Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
- Trial name
- NCT05673356
- Testing
- Arthroscopic anterior cruciate ligament reconstruction with quadriceps tendon bone autograft (QTB)
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Anterior Cruciate Ligament Injury
Light Load Blood Flow Restriction Training in Anterior Cruciate Ligament Reconstruction Patient Rehabilitation
This study is examining the post-operative rehabilitation of anterior cruciate ligament (ACL) reconstruction patients within the National Health Service (NHS).
- Trial name
- NCT03419169
- Testing
- Light load BFR resistance training, Heavy load resistance training
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Anterior Cruciate Ligament Injuries, Cartilage Degeneration
Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction
A randomized controlled clinical study was conducted to elucidate the relationship between the lower extremity biomechanics of patients undergoing early gait training after ACLR surgery.The relationship between the biochemical…
- Trial name
- NCT06368544
- Testing
- lower-body positive-pressure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital