Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Knee Injuries
Clinical Trial Comparing Three Anterior Cruciate Ligament Reconstructive Procedures
The objective of this prospective study is to assess the clinical, functional and radiological outcomes of three different ACL reconstruction procedures: Bone Patella Bone graft, Single bundle hamstring graft and anatomical…
- Trial name
- NCT00418964
- Testing
- Single bundle hamstring, Double bundle hamstring, Bone patellar tendon bone
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Comparative Evaluation of Functional Results and Survival Rate of Peroneus Longus Tendon - PLT and Hamstring Tendon - HT Used for Reconstruction of the Anterior Cruciate Ligament.
Comparative evaluation of functional results and survival rate of peroneus longus tendon - PLT and hamstring tendon - HT used for reconstruction of the anterior cruciate ligament.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05579067
- Testing
- ACL Reconstruction using an autograph of the peroneus longus tendon, folded twice., ACL Reconstruction using an autograph of Hamstrings muscle tendons.
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Anterior Cruciate Ligament Injury, Knee Injury
Anterior Cruciate Ligament (ACL) Tunnel Widening Comparing All-inside and Interference Screw Fixation Technique
The purpose of this study is to evaluate the incidence and degree of bone tunnel widening between two groups who have undergone anterior cruciate ligament reconstructive surgery.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, ACL Injury
- Trial name
- NCT02052856
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
The Effectıveness Of Structured Myofascial Chain Exercise Training After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament reconstruction(ACLR) surgery accepts best choices which condicions are totaly ruptured ACL or partial ruputures when patients with high activity level.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05423184
- Testing
- Exercise Therapy For Lower Extremities, Exercise Therapy For Myofascial Chains
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Anterior Cruciate Ligament Injury
Effect of Adding Vastus Medialis Nerve Block to Adductor Canal Block After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction is frequently associated with moderate to severe postoperative pain, which can delay mobilization and rehabilitation.
- Trial name
- VAMA (NCT07683078)
- Testing
- Adductor Canal Block (ACB) Only, Vastus Medialis Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
ACL Tear
Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier
The goal of this observational study is to compare patient outcomes for reconstructive surgery of ACL tears. This study utilizes two randomized groups, one being the control group that receives standard ACL reconstructive…
- Trial name
- BioACL (NCT05582226)
- Testing
- ACL reconstruction, Mesenchymal stem cell implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Andrews Research & Education Foundation
Anterior Cruciate Ligament Injuries
All-Inside Single-Bundle for Anterior Cruciate Ligament Reconstruction With Full Thickness of the Peroneus Longus Tendon Compared to the Six-strand-hamstring Autograft (ACL)
Anterior cruciate ligament reconstruction is the current gold standard for restoring knee stability. Hamstring tendon (HT) autograft is the most popular graft choice for ACL reconstruction worldwide.
- Trial name
- ACL (NCT05580133)
- Testing
- anterior cruciate ligament reconstruction
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Anterior Cruciate Ligament
Effects of Femoral vs Saphenous Nerve Blocks on Function After ACL Repair
The primary objective of the study is to compare motor strength in knee extension between two groups of patients. One group receiving a proximal thigh block of the femoral nerve, and one receiving a distal thigh block of the…
- Trial name
- NCT01919658
- Testing
- nerve block
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Robert A. Gallo
Pain
A Trial Assessing the Outcome of Celecoxib Administration Versus Placebo Following Anterior Cruciate Ligament (ACL) Reconstruction
The aim of this study is to directly compare the clinical outcomes of both the celecoxib and placebo groups following anterior cruciate ligament (ACL) reconstruction. The study will have short and long term goals.
- Trial name
- NCT01186887
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
ACL Tears
The Effect of Tranexamic Acid Vs Torniquet on Visual Clarity in Knee Arthroscopic ACL Reconstruction
Study Objective: The study aims to determine if tranexamic acid (TXA) is as effective as a tourniquet in improving visual clarity during arthroscopic ACL reconstruction surgery.
- Trial name
- NCT06781021
- Testing
- Tourniquet, TXA
- Where
- Jamaica
- Volunteers
- 60 people
- Sponsor
- The University of The West Indies
Anterior Cruciate Ligament Injuries
Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction
This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT)…
- Trial name
- NCT07346326
- Testing
- Hamstring Tendon Autograft Harvest and ACL Reconstruction, Peroneus Longus Tendon Autograft Harvest and ACL Reconstruction
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Khyber Medical University Peshawar
Bone Graft; Complications, ACL Injuries
Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction
All patients will be randomly assigned using a computer randomization algorithm to one of two matched cohort groups. Patients will not be advised which group they belong to until after the completion of the study.
- Trial name
- BTB BackFill (NCT06975306)
- Testing
- autologous bone grafts, Demineralized bone matrix (DBM)
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Arizona
Anterior Cruciate Ligament Injuries
Infection Rates Between Using of Vancomycin Versus Gentamycin in Primary ACLR
The purpose of the study is to compare the efficacy of Vancomycin versus Gentamycin , in reducing infection rates following Anterior Cruciate Ligament Reconstruction .
- Trial name
- ACLR (NCT06050785)
- Testing
- Vancomycin
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain, Anterior Cruciate Ligament Injury
Combined Saphenous Nerve and IPACK Blocks Versus Infiltration Analgesia After Anterior Cruciate Ligament Reconstruction
A lot of patient have posterior knee pain after ACL reconstruction despite saphenous nerve block. Recently a new block has been described, know as IPACK block (interspace between the popliteal artery and the capsule of the…
- Conditions
- Postoperative Pain, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03680716
- Testing
- Ropivacaine injection
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Anterior Cruciate Ligament Injury, Knee Injuries
Sensory Deficit Following ACL Reconstruction: PRF Pilot Study
Pilot, single-center, non-randomized, parallel-group clinical study designed to assess whether intraoperative application of autologous platelet-rich fibrin (PRF) at the bone-patellar tendon-bone (BPTB) donor site reduces…
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injuries, Sensory Disorders, Bone-Patellar Tendon-Bone Autograft
- Trial name
- PRF-ACL (NCT07257666)
- Testing
- Platelet-rich fibrin (PRF), Standard Closure (Control)
- Where
- Serbia
- Volunteers
- 53 people
- Sponsor
- University of Belgrade
Injury of Anterior Cruciate Ligament
Adductor Canal Block: Continuous Infusion Versus Automatic Intermittent Bolus
The aim of this prospective, randomized , blinded study is to compare two different infusion techniques (continuous VS intermittent automatic bolus) to assess the effects of postoperative analgesia after Day-Case anterior…
- Trial name
- NCT02589288
- Testing
- Continuous Infusion of ropivacaine 0.2%, Automatic Intermittent Bolus of ropivacaine 0.2%
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ASST Gaetano Pini-CTO
Rupture of Anterior Cruciate Ligament
Quadriceps Function Prior to Anterior Cruciate Ligament Reconstruction
Patients who are diagnosed with an isolated tear of the anterior cruciate ligament and scheduled for arthroscopic reconstruction using bone-patellar tendon-bone autograft will be recruited to participate.
- Trial name
- NCT00971451
- Testing
- cryotherapy, TENS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Anterior Cruciate Ligament Rupture
Central Sensitization Symptoms and Psychosocial Factors in Athletes After ACL Reconstruction
The main research objective of this study is whether athletes who have sustained an anterior cruciate ligament injury, experience chronic nociplastic pain and psychosocial factors, including kinesiophobia and pain…
- Trial name
- NCT04393129
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- University of Thessaly
Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes
Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction
This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft.
- Conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation, Strength Outcomes, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- GRAFT-ACL (NCT07523854)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Ligament; Laxity, Knee, Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament-reconstruction: Quadriceps Tendon or Hamstrings Tendon? A Prospective Trial
The purpose of this study is to determine whether there is a difference in muscle strength after anterior cruciate ligament comparing 2 surgery technics. Using either autograft hamstrings tendon or a autograft quadriceps tendon.
- Trial name
- NCT02173483
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital