Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament Injuries
Operant Conditioning After ACL Reconstruction
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT05519345
- Testing
- Operant Conditioning, Control
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Anterior Cruciate Ligament Rupture
Initial Graft Tension and ACL Surgery
The anterior cruciate ligament (ACL) is one of four strong ligaments connecting the bones of the knee joint. If overstretched, the ACL can tear. Reconstruction of a torn ACL is now a common surgical procedure.
- Trial name
- NCT00434837
- Testing
- Initial graft tension during ACL reconstruction surgery
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
ACL - Anterior Cruciate Ligament Rupture
SharkScrew ACL RCT
This prospective, randomized controlled trial will compare three tibial interference screw types used for graft fixation during primary anterior cruciate ligament (ACL) reconstruction: a polyetheretherketone (PEEK) screw, a…
- Trial name
- NCT07830953
- Testing
- ACL Reconstruction with a Biocomposite Screw, ACL Reconstruction using a PEEK Screw, ACL Reconstruction using an Allograft Screw
- Where
- Austria
- Volunteers
- 33 people
- Sponsor
- Austrian Workers Compensation Board Styria
Anterior Cruciate Ligament Rupture
Assessing the Efficacy of a Preoperative Navigation System in Anterior Cruciate Ligament Reconstruction
The ACL surgery robot features a preoperative navigation system that enhances the precision of bone tunnel placement. As the first dual-bundle reconstruction surgical robot developed in China, it integrates advanced technology to…
- Trial name
- NCT06858930
- Testing
- ACL footprint localization after preoperative navigation executed by robotic arm, ACL footprint localization after preoperative navigation executed by rmanual execution
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
ACL Surgery
Muscle Function Following Anterior Cruciate Ligament Reconstruction: Impaired Power Output in Physically Active Individuals
The goal of this clinical trial is to to determine the extent of the association between objective changes in the muscle function of the knee extensors (strength and power) and the function reported by the patient following ACL…
- Trial name
- ReGAIN (NCT07765173)
- Testing
- assessment
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Reconstruction With a Periosteal - Patellar Tendon - Bone Autograft - The Kocabey Press-Fit Technique
This study aims to evaluate the clinical and radiological outcomes of patients undergoing anatomical single-bundle anterior cruciate ligament reconstruction with periosteal-patellar tendon-bone autograft and press-fit tibial…
- Trial name
- NCT06190223
- Testing
- Anterior cruciate ligament (ACL) reconstruction with a periost-patellar-tendon-bone (PPTB) autograft and a tibial press-fit technique
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara City Hospital Bilkent
Knee Injuries
Establishing the Clinical Significance Values of the Lysholm Knee Score
The goal of this observational study is to learn about patients who will undergo anterior cruciate ligament reconstruction. The main questions it aims to answer are: What is the minimal clinically important difference value of…
- Trial name
- NCT06571227
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Kırklareli University
Anterior Cruciate Ligament Injury, Knee Injuries
Bone Tunnel Widening Following ACL Reconstruction
Hypothesis 1: There is less tunnel-widening with bone-patella tendon-bone graft compared with the hamstring graft when the same fixation method is used.
- Trial name
- NCT00198042
- Testing
- Surgical reconstruction of the ACL
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
ACL Reconstruction
Psychological and Physiological Parameters for Return-to-sport After ACL Reconstruction
Injuries to the anterior cruciate ligament are common and are usually treated with reconstruction and subsequent rehabilitation. Many people succeed in return to sport (RTS), but not to the original level.
- Trial name
- ACL-RTS (NCT07259083)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Johannes Kepler University of Linz
Anterior Cruciate Ligament Rupture
Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is surgery that is done to repair a damaged ligament in the knee. In this study we will look at whether the femoral nerve block, a commonly used method for pain relief after ACL…
- Trial name
- NCT00022854
- Testing
- Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Pittsburgh
Anterior Cruciate Ligament Injury
Quadrupled Semitendinosus Graft in Anterior Cruciate Ligament Reconstruction
Randomized controlled trial comparing reconstruction of anterior cruciate ligament (ACL) with autologous quadrupled semitendinosus graft or with both semitendinosus and gracilis.
- Trial name
- NCT03433170
- Testing
- Quadrupled semitendinosus graft, ST-Gracilis graft
- Where
- Colombia
- Volunteers
- 42 people
- Sponsor
- Fundacion Clinica Valle del Lili
Anterior Cruciate Ligament (ACL) Reconstruction
Gabapentin Premedication for ACL Reconstruction: RCT
This double blind randomized control trial will enroll 100 participants ages 12-18 years, undergoing ACL repair. Participants receive gabapentin or placebo preoperatively.
- Trial name
- NCT03417479
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
ACL - Anterior Cruciate Ligament Rupture, ACL Injuries
Non-Narcotic Pain Control After ACL Reconstruction
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses…
- Trial name
- NCT06973785
- Testing
- dispense of study drug, Ketorolac
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Anterior Cruciate Ligament (ACL)
Comparison of Standard ACL Reconstruction Versus TARS-Augmented Reconstruction
This study is designed to compare standard anterior cruciate ligament (ACL) reconstruction using hamstring autograft with ACL reconstruction augmented using the Tape Active Reconstruction System (TARS).
- Trial name
- NCT07418476
- Testing
- ACL Reconstruction, TARS-Augmented ACL Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Anterior Cruciate Ligament Injury
Anterior Cruciate Ligament Reconstruction Using Single Bundle and Double Bundle Techniques
Anterior Cruciate Ligament (ACL) reconstruction surgery has greatly advanced over the last 20 years. However, data in the literature reveal that approximately 15-25% of patients undergoing surgery still do not present optimal…
- Trial name
- KR (NCT01358656)
- Testing
- Single bundle anterior cruciate ligament reconstruction, Double bundle anterior cruciate ligament reconstruction
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Vita Care
Anterior Cruciate Ligament Injuries
Graft Selection in Anatomic Anterior Cruciate Ligament Reconstruction
A rupture of the anterior cruciate ligament (ACL) is a severe injury of the knee. The current gold Standard treatment for young and active patients with instability, is a surgical ACL reconstruction.
- Trial name
- Grafttype (NCT03073083)
- Testing
- Hamstring tendon autograft, Pattella tendon autograft, Quadriceps tendon autograft
- Where
- 2 sites in Netherlands
- Volunteers
- 439 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Anterior Cruciate Ligament Injuries
Muscle Architecture and Anterior Cruciate Ligament
The aim of this study is to examine the effects of plyometric training on biceps femoris longus (BFl) and vastus lateralis (VL) muscle architecture in individuals with anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04690127
- Testing
- Plyometric Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-Articular Tenodesis Among High Demand Patients
Anterior Cruciate Ligament Reconstruction with and without Lateral Extra-Articular Tenodesis between high demand patients
- Trial name
- NCT05962580
- Testing
- Isolated anterior cruciate ligament reconstruction with lateral extra articular tenodesis, Isolated anterior cruciate ligament reconstruction only
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
ACL - Anterior Cruciate Ligament Deficiency, ACL Injury
Tourniquet Use in Anterior Cruciate Ligament Repair
The purpose of this study is to assess the intra-operative and post-operative effects of tourniquet use during ACL reconstruction. We hypothesize that: 1.
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
- Trial name
- NCT05931627
- Testing
- Patients undergoing ACL reconstruction with or without a tourniquet
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Anterior Cruciate Ligament Injury
Evaluation of the Effect of Using WeChat Applet to Intervene in the Home Functional Exercise of Patients After Anterior Cruciate Ligament Reconstruction Based on the Health Belief Model
Based on the home rehabilitation exercise of patients undergoing ACL reconstruction, the existing WeChat applet of sports medicine of the Third Hospital of Beijing Medical University is optimized to be used as a health education…
- Trial name
- NCT04957810
- Testing
- WeChat Mini Program
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital