Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Postoperative Pain
Lumbar Plexus Catheter Versus Femoral Nerve Catheter for Postoperative Pain After Anterior Cruciate Ligament (ACL) Repair
Randomized trial comparing lumbar plexus catheter versus femoral nerve catheter (single-shot femoral block as control group) for postoperative pain control after anterior cruciate ligament repair in children (age 11-21).
- Trial name
- NCT01068275
- Testing
- lumbar plexus catheter, femoral nerve catheter, single-shot femoral block
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Seattle Children's Hospital
ACL Tear
ACL Bone Health and Loading Study
The purpose of this study is to look at the effects of bone density on lower extremity loading mechanics using Blood Flow Restriction (BFR) to provide the control group for bone health.
- Trial name
- ACLBONE (NCT04682392)
- Testing
- Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Candice Dunkin, MS, LAT, ATC
Knee Injuries
Clinical Evaluation of dCELL® ACL Scaffold for Reconstruction of the Anterior Cruciate Ligament
The safety and performance of dCELL® ACL Scaffold will be evaluated in 40 patients who have been implanted with the investigational product following a ruptured anterior cruciate ligament (ACL) of the knee.
- Trial name
- NCT02540811
- Testing
- dCELL® ACL Scaffold
- Where
- 8 sites in Poland, Spain and 1 more
- Volunteers
- 40 people
- Sponsor
- Tissue Regenix Ltd
Anterior Cruciate Ligament Reconstruction
Anesthesic Techniques for Surgery of the Anterior Cruciate Ligament of the Knee in Ambulatory Surgery. Randomized Pilot Monocentric Trial
Surgery of the anterior cruciate ligament of the knee is frequently a young patient surgery. The post-operative pain of this surgery is managed according to recommendation.
- Trial name
- CLICA (NCT02257164)
- Testing
- Femoral nerve block, obturator nerve block, intraarticular injection
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Comparison of Anterior Sciatic Nerve Block and Adductor Magnus Muscle Plane Block for Anterior Cruciate Ligament Surgery
Anterior cruciate ligament (ACL) reconstruction is frequently associated with moderate-to-severe postoperative pain despite its arthroscopic nature, owing to the complex sensory innervation of the knee involving the femoral…
- Trial name
- NCT07601529
- Testing
- Adductor canal block, Anterior sciatic nerve block, Adductor magnus plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Anterior Cruciate Ligament Rupture
Central Sensitization Symptoms and Psychosocial Factors in Athletes After ACL Reconstruction
The main research objective of this study is whether athletes who have sustained an anterior cruciate ligament injury, experience chronic nociplastic pain and psychosocial factors, including kinesiophobia and pain…
- Trial name
- NCT04393129
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- University of Thessaly
Complete Tear, Knee, Anterior Cruciate Ligament
Gait Rehabilitation Following an Anterior Cruciate Ligament Reconstruction
A randomized control trial where subjects following an anterior cruciate ligament reconstruction will be randomized to either a control group who will receive the normal rehabilitation or an experimental group who will perform a…
- Trial name
- NCT02930239
- Testing
- Gait rehabilitating with reduced bodyweight, Standardized rehabilitation following an anterior cruciate ligament reconstruction at Linkoping University Hospital
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Anterior Cruciate Ligament Reconstruction
Inter-rater Reliability of the GNRB Arthrometer
Although clinical examination is commonly used to diagnose an anterior cruciate ligament (ACL) injury, the method is subjective.
- Trial name
- NCT07200700
- Testing
- Knee laxity arthrometer
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Vastra Gotaland Region
Rupture of Anterior Cruciate Ligament, Muscle Degeneration
Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)
Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year.
- Conditions
- Rupture of Anterior Cruciate Ligament, Muscle Degeneration, Gait, Unsteady
- Trial name
- RATE (NCT02939677)
- Testing
- Targeted exercise
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- University of Southern Denmark
Anterior Cruciate Ligament Rupture, Acute Pain
Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
An adequate balance between analgesia and motor function is an essential requirement to facilitate functional recovery and early discharge after anterior cruciate ligament (ACL) reconstruction surgery. Proximal nerve blocks (i.e.
- Conditions
- Anterior Cruciate Ligament Rupture, Acute Pain, Pain, Postoperative, Knee Injuries
- Trial name
- NCT05068063
- Testing
- Bupivacaine Injection, normal Saline
- Where
- 2 sites in Chile
- Volunteers
- 48 people
- Sponsor
- University of Chile
Anterior Cruciate Ligament Injury
Remnant Preservation and Tibial Tunnel Widening After ACL Reconstruction
Anterior Cruciate Ligament (ACL) reconstruction is one of the most commonly performed orthopedic procedures. Tibial tunnel widening is a recognized postoperative complication that may affect graft stability and long-term…
- Trial name
- NCT07236593
- Testing
- Stump-Suturing ACL Reconstruction, Stump-Resection ACL Reconstruction
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Exploring Prolonged AMR in ACL Reconstructed Patients
The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, ACL
- Trial name
- NCT06430775
- Where
- Belgium
- Volunteers
- 190 people
- Sponsor
- University Ghent
Anterior Cruciate Ligament Injuries
Society for Pediatric Anesthesia Improvement Network- Anterior Cruciate Ligament Reconstruction Outcomes Project
The primary objective is to create a multicenter registry which captures information relating to the perioperative anesthesia course and management of children undergoing anterior cruciate ligament reconstruction and to examine…
- Trial name
- SPAIN-ACL (NCT04329117)
- Where
- 2 sites in United States
- Volunteers
- 526 people
- Sponsor
- Boston Children's Hospital
Anterior Cruciate Ligament Reconstruction
Multi-scale Modeling for Predictive Characterization of Ligaments and Grafts Behavior in ACL Reconstruction
The objective of this clinical trial is provide in vivo data thus to model the ligament biomechanical behavior within the physiologically healthy joint and to use the implemented model to predict risk and success rates focusing…
- Trial name
- MULTI-ACL (NCT06058494)
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
ACL Reconstruction
Efficacy and Tolerability of a Nutritional Supplement, Plactive Progen, in ACL Reconstruction
This was a prospective, multicenter, randomized, open-label, phase IV trial to compare the efficacy of supplementation with plasma proteins, hydrolyzed collagen (CH), a complex of HA-CS (HC-15), and vitamin C combined with a…
- Trial name
- NCT03355651
- Testing
- PROGEN
- Volunteers
- 80 people
- Sponsor
- OPKO Health, Inc.
Anterior Cruciate Ligament Reconstruction
Effect of PRP Versus BMC in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is an important stabilizer of knee during daily activity and exercise. The ruptured ACL need to be reconstructed by a new tendon graft which passed the bone tunnel and joint during operation.
- Trial name
- NCT05191732
- Testing
- Platelet-Rich Plasma; Bone marrow concentrate
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
ACL Injury, Meniscus Tear
MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)
This is a multicenter randomized, placebo-controlled trial to assess whether a 6-month course of oral montelukast after ACL reconstruction reduces systemic markers of inflammation and biochemical and imaging biomarkers of…
- Conditions
- ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
- Trial name
- MOCHA (NCT04572256)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Austin V Stone
Knee Ligament Injury
Performance and Safety of the Polylactic Interference Screw Used in Anterior Cruciate Ligament Reconstructions
The evaluation of the clinical data has demonstrated the conformity of the Polylactic Interference Screw (PIS), with the relevant essential requirements for its use in orthopaedic applications.
- Trial name
- NCT04122677
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Biomatlante
Anterior Cruciate Ligament Reconstruction
Assessment of Gait Adaptation Due to an Asymmetric Walking Protocol
The purpose of this work is to conduct a comparative research-focused study to evaluate the effectiveness of how purposefully induced asymmetric walking protocols restore healthy, symmetric limb loading in individuals following…
- Trial name
- NCT05968729
- Testing
- Active Comparator: 0.25 m/s asymmetric session first, Active Comparator: 0.50 m/s asymmetric session first
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Anterior Cruciate Ligament Rupture
Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients…
- Trial name
- NCT05286307
- Testing
- IPACK block
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- NYU Langone Health