Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament Reconstruction, Post-traumatic Osteoarthritis
STABILITY: Physical Activity Intervention at 7 Years Post-Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) ruptures are very common knee injuries amongst youth involved in sports and are often treated through ACL reconstruction surgeries.
- Trial name
- NCT05152758
- Testing
- PARx
- Where
- Canada
- Volunteers
- 196 people
- Sponsor
- Western University, Canada
Anterior Cruciate Ligament Injury, Knee Injury
Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction
While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes.
- Trial name
- NCT02148172
- Testing
- Standard Plyometric Training, Plyometric Training with BWS
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Montana
Knee Injuries
Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws
In this randomized controlled trial the investigators will compare the results after primary anterior cruciate ligament (ACL) reconstruction using two different methods for femoral fixation of a bone-patellar tendon-bone (BPTB)…
- Trial name
- NCT02918734
- Testing
- Endobutton CL BTB, Metal interference screw
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Injury of the Anterior Cruciate Ligament (ACL)
Clinical and Functional Outcomes 2 Years After ACL Repair and InternalBrace Ligament Augmentation in Comparison With ACL Reconstruction
The aim of this study is to assess the clinical, biomechanical and functional outcome 2 years after anterior cruciate ligament (ACL) repair and InternalBraceTM augmentation now in direct comparison to ACL reconstruction and to…
- Trial name
- RetroBRACE II (NCT04429165)
- Testing
- collection of Patient Reported Outcome (PRO) data, collection of anthropometric and clinical functional data, gait analysis
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Pain, Anterior Cruciate Ligament Reconstruction
Comparison of Two Techniques for Placement of Perineural Femoral Catheters.
The purpose of this study is to assess the efficacy of the hydrolocalization technique for placement of femoral perineural catheters in comparison with stimulating catheters. A non inferiority trial.
- Trial name
- HLOCSTIM2 (NCT01726192)
- Testing
- Placement of a femoral catheter with the hydrolocalization technique, Placement of a femoral neurostimulating catheter
- Where
- 2 sites in Greece, Italy
- Volunteers
- 50 people
- Sponsor
- Attikon Hospital
ACL Tear
Psychological Factors Influencing the Patient-reported and Functional Outcome of ACL Reconstruction and Their Sex-specific Differences
Psychological parameters among patients undergoing ACL reconstruction and their impact on the patient-reported and functional outcome of reconstruction will be prospectively evaluated
- Trial name
- NCT06156501
- Testing
- ACL Reconstruction
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction
Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy
This three-year research project aims to test the hypothesis that strain and displacement characteristics of human soft tissues are influenced by (1) habitual physical activity, (2) functional impairment, and (3) training…
- Conditions
- Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Ultrasound Evaluation
- Trial name
- NCT07485530
- Testing
- blood flow restriction training, nordic exercise training
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pain, Postoperative
The Effect of Femoral Nerve Block on Postoperative Opioid Use After Anterior Cruciate Ligament (ACL) Reconstruction
This study evaluates the effect of a femoral nerve block on opioid requirements following anterior cruciate ligament (ACL) reconstruction. This is a double blind, prospective randomized controlled trial.
- Trial name
- NCT00175630
- Testing
- Administration of a femoral nerve block (bupivacaine HCL)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Injuries
Objective Results of Anterior Cruciate Ligament Reconstruction With and Without Internal Suture Augmentation Technique
The purpose of this study is (1) To report, compare and corelate the patient reported outcomes (PRO) (IKDC score, Lysholm Score) and range of motion (ROM) among patients following hamstring autograft ACLR with and without…
- Trial name
- NCT04906538
- Testing
- all- inside anterior cruciate ligament reconstruction
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Ain Shams University
Anterior Cruciate Ligament Reconstruction
Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint
The purpose of this study is to compare the tomographic results of patients who underwent single-bundle anterior cruciate ligament reconstruction at the investigator's institution using the transtibial, accessory medial portal…
- Trial name
- NCT02795247
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Anterior Cruciate Ligament Rupture
Blood Flow Restriction Following ACL Reconstruction
The main objective is to determine the impact of Blood Flow Restriction (BFR) therapy, in comparison to a standard rehabilitation protocol, on preventing atrophy, improving quadriceps strength and improving functional outcomes of…
- Trial name
- BFR (NCT03758755)
- Testing
- Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Inova Health Care Services
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction
ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws
The goal of this clinical trial is to compare the outcome of 2 different screws for Anterior cruciate ligament reconstruction. The main question is if the human allogeneic cortical bone screw reduces tunnel widening in comparison…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injury
- Trial name
- NCT06357091
- Testing
- ACL reconstruction with Shark Screw ACL®, ACL reconstruction with biocomposite screw (Mecta)
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Alexander Rofner-Moretti
Anterior Cruciate Ligament Injuries
Muscle Architecture and Anterior Cruciate Ligament
The aim of this study is to examine the effects of plyometric training on biceps femoris longus (BFl) and vastus lateralis (VL) muscle architecture in individuals with anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04690127
- Testing
- Plyometric Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Anterior Cruciate Ligament Injuries
Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction
This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT)…
- Trial name
- NCT07346326
- Testing
- Hamstring Tendon Autograft Harvest and ACL Reconstruction, Peroneus Longus Tendon Autograft Harvest and ACL Reconstruction
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Khyber Medical University Peshawar
Pain Relief After Arthroscopic Anterior Cruciate Ligament Reconstruction
Oral Melatonin With Intra Articular Analgesia on Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction
Anterior Cruciate Ligament Reconstruction (ACLR) is a common orthopedic procedure that is accompanied by moderate to severe postoperative pain and is primarily performed on an outpatient basis.
- Trial name
- ACLR (NCT07096635)
- Testing
- Melatonin, Starch tablets
- Volunteers
- 50 people
- Sponsor
- Assiut University
Weight-bearing Deficits
Weight-bearing Measuring Device Following Anterior Cruciate Ligament Reconstruction
The objective of this clinical trial is to in determining weight-bearing deficits following anterior cruciate ligament reconstruction.
- Trial name
- NCT01127685
- Testing
- Smart_Step weight bearing insole
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
ACL Tear, ACL Injury
The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults
A prospective study, with outcomes including re-rupture rate and return to sport will be collected following ACL reconstruction.
- Conditions
- ACL Tear, ACL Injury, Arthroscopy, Anterior Cruciate Ligament Tear
- Trial name
- FACL (NCT04178538)
- Testing
- ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation, Standard ACL reconstruction with all inside technique
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marshall University
Arthroscopic Anterior Cruciate Ligament Reconstruction
Pain Evaluation After Anterior Cruciate Ligament (ACL) Ligamentoplasty
The "All-inside" method is a new minimally invasive procedure for anterior cruciate ligament reconstruction (ACL). It consists of incomplete bone tunnels drilling and cortical fixation.
- Trial name
- NCT01448278
- Testing
- "All-inside", Classical technique
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hospital Ambroise Paré Paris
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction Rehabilitation
Eccentric Phase Biomechanics of the Countermovement Jump After Anterior Cruciate Ligament Reconstruction
Purpose: This study aims to better understand how force is produced during a vertical jump in individuals approximately six months after anterior cruciate ligament reconstruction compared with healthy individuals.
- Trial name
- DECAL (NCT07448064)
- Testing
- Countermovement Jump Force Platform Assessment, Isokinetic Test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
ACL Reconstruction
Application of Multiple Vertical Jump Tests in Return-to-Play Assessment for Anterior Cruciate Ligament Reconstruction Athletes
Anterior cruciate ligament (ACL) injury is a common sports-related injury, particularly in sports that require extensive jumping and cutting movements.
- Trial name
- RTP-VJ (NCT07297511)
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University