Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Reconstruction Made With Hamstring Tendon And Quadriceps Tendon Autografts
Anterior cruciate ligament reconstruction (ACLR) is one of the most common procedure all around the world, however optimal graft source for ACLR still remains controversial.
- Trial name
- NCT04940169
- Testing
- anterior cruciate ligament recontruction
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- SB Istanbul Education and Research Hospital
Knee Ligament Injury
TEL and Clam Shell Exercises Affect After ACL
The purpose of this study to determine the effects of the addition of isolated hip strengthening exercises to traditional rehabilitation after Anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT05856071
- Testing
- goniometer, clamshells exercises, traditional physical therapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Reconstruction, Quadriceps Muscle Weakness
Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction
Quadriceps muscle dysfunction persists for years after anterior cruciate ligament reconstruction (ACLR) and is related to poor self-reported outcomes, altered movement patterns and joint loading associated with post-traumatic…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Quadriceps Muscle Weakness, Transcranial Direct Current Stimulation
- Trial name
- NCT04504344
- Testing
- Anodal transcranial direct current stimulation (tDCS) - Soterix Medical Inc, 1x1 tDCS (conventional)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Arcadia University
Anterior Cruciate Ligament Rupture
Are Opioids Needed After ACL Reconstruction
As the public health sector continues to confront the opioid epidemic, orthopaedic surgeons must revisit pain management protocols to reduce unnecessary opioid prescriptions.
- Trial name
- NCT04285853
- Testing
- Oxycodone
- Where
- 3 sites in United States
- Volunteers
- 98 people
- Sponsor
- Emory University
Anterior Cruciate Ligament Injury
Psychological Readiness and Return to Sport After ACL Reconstruction
The goal of this observational study is to evaluate psychological readiness, kinesiophobia, subjective knee function, sport activity level, and return-to-sport status in athletes who have undergone primary anterior cruciate…
- Trial name
- NCT07733895
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Anterior Cruciate Ligament Reconstruction
Fixed Versus Adjustable Loop in ACL Reconstruction
Study Aims and Objectives: To investigate the following null hypothesis: that there is no difference in clinical and functional outcome when comparing outcomes of Anterior Cruciate Ligament (ACL) reconstruction when comparing…
- Trial name
- NCT03184922
- Testing
- Adjustable versus fixed suspensory loop femoral side graft fixation
- Where
- United Kingdom
- Volunteers
- 165 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
ACL Reconstruction
Home Vs. Physiotherapy Supervised Rehabilitation After ACL Reconstruction
This study was designed to determine whether or not there were any differences in knee range of motion, both statically and during gait, sagittal plane knee laxity, and quadriceps and hamstrings strength in patients three months…
- Trial name
- NCT00564837
- Testing
- Home-based rehabilitation program, Physiotherapy-supervised rehabilitation program
- Where
- Canada
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament/Surgery
Use of Simplified Pain Questionnaire Among People Receiving Anterior Cruciate Ligament (ACL) Knee Surgery?
The goal of this randomized clinical trial is to compare opioid consumption among patients who receive a binary pain scale compared to those who receive a standard 10-point pain scale after undergoing anterior cruciate ligament…
- Trial name
- NCT07065266
- Testing
- Binary pain questionnaire, Numerical Pain Rating Scale (NPRS)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Stanford University
Anterior Cruciate Ligament Reconstruction Rehabilitation
Evaluation of Home-based Telerehabilitation Platform to Augment Orthopedic Rehabilitation
The goal of this study is to assess the feasibility of utilizing a telehealth rehabilitation platform to increase patient access for individuals who have undergone orthopedic surgery.
- Trial name
- NCT06973642
- Testing
- Software as a Medical Device (WizeCare)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Mississippi Medical Center
Anterior Cruciate Ligament Injuries, Postoperative Pain
Multimodal Analgesia vs. Femoral Block in ACL Surgery
This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative
- Trial name
- MAPvsFTB (NCT06936995)
- Testing
- Preemptive Multimodal Intravenous Analgesia, Femoral Triangle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara University
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Anterior Cruciate Ligament
Effects of Femoral vs Saphenous Nerve Blocks on Function After ACL Repair
The primary objective of the study is to compare motor strength in knee extension between two groups of patients. One group receiving a proximal thigh block of the femoral nerve, and one receiving a distal thigh block of the…
- Trial name
- NCT01919658
- Testing
- nerve block
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Robert A. Gallo
Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction
Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study
Postoperative pain is usually treated with opioids that have undesirable and sometimes dangerous side effects (e.g., vomiting and respiratory depression)-and yet over 80% of patients still experience inadequate pain relief.
- Conditions
- Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction, Ankle Arthrodesis or Arthroplasty, Hallux Valgus Correction
- Trial name
- NCT03481725
- Testing
- ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio)
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Diego
Anterior Cruciate Ligament Injury, Pain; Catheter (Other)
On-Q Catheter Caregiver Education
The present study aims to compare caregiver satisfaction and efficacy between two modes of patient education materials (PEMs): media based and print based.
- Conditions
- Anterior Cruciate Ligament Injury, Pain; Catheter (Other), Satisfaction, Personal
- Trial name
- NCT03372889
- Testing
- Patient educaiton materials - Print based, Patient educaiton materials - Media based
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament
The Long-term Degradation Outcome of Bilok Screws Used for ACL Reconstruction
The purpose of the study is to evaluate the long term outcome of a poly L-lactic acid / β-tricalcium phosphate (BILOK) biodegradable interference fixation screw used for arthroscopic bone-patellar tendon-bone ACL…
- Trial name
- NCT00374491
- Sponsor
- ArthroCare Corporation
Anterior Cruciate Ligament Rupture
Hamstring Muscle Strength After ACL Hamstring Reconstruction
Anterior Cruciate Ligament (ACL) reconstructions using hamstring grafts can be performed using one or two hamstring grafts, the semitendinosus (ST) tendon only, or both the semitendinosus and gracilis (ST/G) tendon.
- Trial name
- HAMSTRING (NCT05464485)
- Testing
- ACL hamstring reconstructions using semitendinosus (ST) tendon only, ACL hamstring reconstructions using semitendinosus and gracilis (ST/G) tendon
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Isala
ACL Tear, ACL Injury
The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults
A prospective study, with outcomes including re-rupture rate and return to sport will be collected following ACL reconstruction.
- Conditions
- ACL Tear, ACL Injury, Arthroscopy, Anterior Cruciate Ligament Tear
- Trial name
- FACL (NCT04178538)
- Testing
- ACL reconstruction with bone marrow, demineralized bone marix, and internal brace augmentation, Standard ACL reconstruction with all inside technique
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marshall University
ACL Reconstruction, Extracorpereal Shock Wave Therapy
Efficacy of Focused Extracorporeal Shock Wave Therapy After Anterior Cruciate Ligament Reconstruction
The aim of this clinical trial is to determine the effectiveness of fESWT in rehabilitation after ACL reconstruction. The main questions it aims to answer are: Is fESWT applied in addition to conventional physiotherapy effective…
- Trial name
- NCT06688344
- Testing
- fESWT, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Berivan Beril Kılıç
ACL Injury, Anterior Cruciate Ligament Injuries
Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes
The purpose of this research is to find out whether the way information about surgery is presented to patients affects patient satisfaction, knowledge retention, and surgical outcomes such as anxiety
- Trial name
- NCT05273463
- Testing
- Video-Based Intervention, Classroom-Based Intervention
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic