Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament Rupture
Central Sensitization Symptoms and Psychosocial Factors in Athletes After ACL Reconstruction
The main research objective of this study is whether athletes who have sustained an anterior cruciate ligament injury, experience chronic nociplastic pain and psychosocial factors, including kinesiophobia and pain…
- Trial name
- NCT04393129
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- University of Thessaly
Anterior Cruciate Ligament Tear
Moderated Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction
The aim of this study is to determine if there is a difference in post operative rehabilitation after anterior cruciate ligament (ACL) reconstruction surgery while using moderated blood flow therapy vs. standard physical therapy.
- Trial name
- Delfi (NCT02911909)
- Testing
- Delfi, Standard rehabilitation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Missouri-Columbia
Rupture of Anterior Cruciate Ligament
Multicenter Orthopaedics Outcomes Network for ACL Reconstructions
The purpose of this study is to determine the effect of modifiable risk factors on knee function, osteoarthritis, and re-rupture of the anterior cruciate ligament (ACL) following ACL reconstruction.
- Trial name
- NCT00463099
- Where
- 8 sites in United States
- Volunteers
- 3,294 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under SA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under spinal anesthesia.
- Trial name
- NCT06048874
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anterior Cruciate Ligament Injuries
Robotic Assistance for Tunnel Positioning in Anterior Cruciate Ligament Reconstruction
Accurate ideal graft tunnel positioning is essential for the successful application of anatomic anterior cruciate ligament (ACL) reconstruction.
- Trial name
- MIRRACL (NCT04183803)
- Testing
- anatomic anterior cruciate ligament (ACL) reconstruction
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anterior Cruciate Ligament Rupture
Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial
The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction.
- Trial name
- NCT04042688
- Testing
- intraarticular administration of tranexamic acid
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Exploring Prolonged AMR in ACL Reconstructed Patients
The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, ACL
- Trial name
- NCT06430775
- Where
- Belgium
- Volunteers
- 190 people
- Sponsor
- University Ghent
Anterior Cruciate Ligament Reconstruction Rehabilitation
Effects of tDCS on Motor Cortex During ACL Recovery
Anterior Cruciate Ligament (ACL) is a prevalent injury, particularly among young and physically active individuals. The efficacy of transcranial direct current stimulation (tDCS) and exercise-based rehabilitation on neuromuscular…
- Trial name
- NCT06818201
- Testing
- NIBS, Rehabilitation
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
ACL - Anterior Cruciate Ligament Rupture
Clinical-randomized Trial of the Effect of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Anterior Cruciate Ligament Reconstruction
With the intention of improving rehabilitation after anterior cruciate ligament reconstruction, the present project investigates the influence of a targeted strength and blood flow restriction training intervention (BFR training)…
- Trial name
- NCT07043569
- Testing
- Resistance Exercise with BFR
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Bone Autograft
Anterior cruciate ligament injuries are one of the most common sports knee injuries. Their effect on the knee joint can be detrimental with patients experiencing instability and progressive damage of the intraarticular…
- Conditions
- Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
- Trial name
- NCT05673356
- Testing
- Arthroscopic anterior cruciate ligament reconstruction with quadriceps tendon bone autograft (QTB)
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
ACL Injury, ACL Reconstruction
Ultrasonic Backscatter Imaging for ACL Reconstruction and Shoulder Diseases
This study explores ultrasonic scattering imaging technology in patients undergoing anterior cruciate ligament (ACL) reconstruction and those with shoulder musculoskeletal disorders.
- Trial name
- NCT06361082
- Testing
- ACL reconstruction
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Anterior Cruciate Ligament Reconstruction
Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction
This is a crossover phase 4 study to evaluate the impact of blood flow restriction on immunometabolism and gene expression in immune cells in individuals undergoing rehabilitation from anterior cruciate ligament reconstruction.
- Trial name
- NCT05012982
- Testing
- AirBand, uninflated AirBand
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Yale University
ACL Deficient Knee
ACLR: Isolated Autograft vs Allograft With Lateral Extra-articular Tenodesis
This study seeks to evaluate the utility of non-irradiated allograft tissue with lateral extra-articular tenodesis (LET) in the setting of anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT06668155
- Testing
- Autograft Group, Allograft with LET Group
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Anterior Cruciate Ligament Injuries, Knee Injuries
The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial
While there are a number studies that have reported on the use of blood flow restriction training (BFRT) in the adult population, there is limited information about the use of BFRT in the adolescent population.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Quadriceps Muscle Atrophy
- Trial name
- NCT05754632
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Connecticut Children's Medical Center
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Clinical and Biological Outcomes of BioBrace-Augmented ACL Reconstruction
This prospective, single-center, single-arm observational cohort study aims to evaluate the clinical, radiological, and arthroscopic outcomes and safety of primary anterior cruciate ligament (ACL) reconstruction augmented with…
- Trial name
- NCT07906860
- Testing
- BioBrace® Reinforced BioInductive Implant
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Anterior Cruciate Ligament Reconstruction, Knee Injury
Quadriceps and Hamstring Activation Timing
The anterior cruciate ligament (ACL) plays a crucial role in maintaining knee stability and enabling dynamic movement. ACL injuries are common, especially among athletes, and reconstruction surgery is frequently performed to…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Knee Injury, Neuromuscular Control
- Trial name
- NCT07532980
- Testing
- Electromyography
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- KTO Karatay University
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-Articular Tenodesis Among High Demand Patients
Anterior Cruciate Ligament Reconstruction with and without Lateral Extra-Articular Tenodesis between high demand patients
- Trial name
- NCT05962580
- Testing
- Isolated anterior cruciate ligament reconstruction with lateral extra articular tenodesis, Isolated anterior cruciate ligament reconstruction only
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Anterior Cruciate Ligament Reconstruction
The Best Method for ACL Reconstruction.
The investigators wish to compare 3 methods for reconstruction of the anterior cruciate ligament using 3 different grafts: bone-patella tendon-bone, hamstrings and iliotibial tract graft, as these methods influence the muscles…
- Trial name
- NCT03192761
- Testing
- ACL reconstruction hamstrings, ACL reconstruction patella tendon, ACL reconstruction iliotibial tract
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Lars Konradsen
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.