Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Cyclop Arthrofibrosis Anterior Cruciate Ligament
Is There a Correlation Between Surgical Technique for Primary Anterior Cruciate Ligament Surgery and the Risk of Subsequent Formation of Fibrous Cyst (Cyclops) in the Knee Joint, Which Leads to the Need for Surgical Removal of the Cyclops?
Fibrous scar tissue formation (Cyclops) after a primary anterior cruciate ligament reconstruction (ACLr) may affect patients' ability to perform work and exercise to such an extent that further arthroscopic surgery may be…
- Trial name
- NCT05301686
- Testing
- Patients with Cyclop lesion
- Where
- Denmark
- Volunteers
- 2,556 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament (ACL) Reconstruction
Gabapentin Premedication for ACL Reconstruction: RCT
This double blind randomized control trial will enroll 100 participants ages 12-18 years, undergoing ACL repair. Participants receive gabapentin or placebo preoperatively.
- Trial name
- NCT03417479
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
ACL Injury
Association Between Neuromuscular Parameters and Functional Assessment After ACL Reconstruction
The anterior cruciate ligament (ACL) injury is common in athletes aged 18 to 35. ACL reconstruction (ACLR) aims to restore knee stability in the process of returning to sports.
- Trial name
- KASTLAB (NCT06524869)
- Testing
- Isokinetic neuromuscular assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Caen
Rupture of Anterior Cruciate Ligament
Quadriceps Function Prior to Anterior Cruciate Ligament Reconstruction
Patients who are diagnosed with an isolated tear of the anterior cruciate ligament and scheduled for arthroscopic reconstruction using bone-patellar tendon-bone autograft will be recruited to participate.
- Trial name
- NCT00971451
- Testing
- cryotherapy, TENS
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Complete Tear, Knee, Anterior Cruciate Ligament
A Study to Compare Two Techniques for the Reconstruction of the Anterior Cruciate Ligament
This is a prospective and randomized trial to compare two different techniques used in normal practice for the reconstruction of the anterior cruciate ligament in arthroscopy.
- Trial name
- ACL (NCT03746470)
- Testing
- ACL reconstruction preserving insertion, ACL reconstruction detaching insertion
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 85 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Anterior Cruciate Ligament Reconstruction
Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction
Scientific Research Question Overall Purpose: Regarding rehabilitation after anterior cruciate ligament reconstruction (ACLR), there is a knowledge gap - a lack of evidence.
- Trial name
- NCT06318039
- Testing
- Novel program, Traditional program
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Linnaeus University
Knee Injuries
Clinical Evaluation of dCELL® ACL Scaffold for Reconstruction of the Anterior Cruciate Ligament
The safety and performance of dCELL® ACL Scaffold will be evaluated in 40 patients who have been implanted with the investigational product following a ruptured anterior cruciate ligament (ACL) of the knee.
- Trial name
- NCT02540811
- Testing
- dCELL® ACL Scaffold
- Where
- 8 sites in Poland, Spain and 1 more
- Volunteers
- 40 people
- Sponsor
- Tissue Regenix Ltd
ACL Reconstruction
Effects of Anodal Transcranial Direct Current Stimulation on Muscle Inhibition After ACL Reconstruction
This randomized controlled trial will investigate the effects of anodal transcranial direct current stimulation (tDCS) on arthrogenic muscle inhibition in athletes following anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT07866963
- Testing
- Anodal Transcranial Direct Current Stimulation (tDCS), Standard Physical Therapy
- Volunteers
- 64 people
- Sponsor
- University of Lahore
Knee Injuries, Anterior Cruciate Ligament (ACL) Reconstruction
OrthoPure™ XT Pilot Clinical Study
To evaluate the clinical safety and obtain preliminary effectiveness data for OrthoPure™ XT device in a small group of US patients at 12 and 24 months.
- Trial name
- NCT03562299
- Testing
- OrthoPure™ XT
- Where
- 3 sites in United States
- Sponsor
- TRX Orthopedics
Post-operative Pain, Quadriceps Muscle Strength
Ultrasound Guided Adductor Canal Versus Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction in Pediatrics
Both Ultrasound guided Adductor Canal Block ( ACB) and Femoral Nerve Block (FNB) has been used to provide postoperative analgesia for knee surgeries.
- Trial name
- NCT03053401
- Testing
- Adductor Canal Block, Femoral Nerve Block, Ultrasound
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Akron Children's Hospital
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Comparative Evaluation of Functional Results and Survival Rate of Peroneus Longus Tendon - PLT and Hamstring Tendon - HT Used for Reconstruction of the Anterior Cruciate Ligament.
Comparative evaluation of functional results and survival rate of peroneus longus tendon - PLT and hamstring tendon - HT used for reconstruction of the anterior cruciate ligament.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05579067
- Testing
- ACL Reconstruction using an autograph of the peroneus longus tendon, folded twice., ACL Reconstruction using an autograph of Hamstrings muscle tendons.
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Rupture of Anterior Cruciate Ligament
COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined
Recent studies on molar surgery have shown that a combination of a glucocorticoid and NSAID or COX-2 selective inhibitor gives better pain relief than either of the drugs used separately.
- Trial name
- NCT01361789
- Testing
- parecoxib, valdecoxib, etoricoxib, Dexamethasone, parecoxib, valdecoxib, parecoxib and dexamethasone
- Where
- Norway
- Volunteers
- 93 people
- Sponsor
- Asker & Baerum Hospital
ACL Tear, ACL - Anterior Cruciate Ligament Deficiency
Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and After Anterior Cruciate Ligament Reconstruction
This prospectively study aims to evaluate the evolution of knee joint proprioception on isokinetic dynamometer before and after Anterior Cruciate Ligament (ACL) reconstruction and its relationships with muscle strength, self…
- Trial name
- PRO-ACL (NCT04058574)
- Testing
- Proprioception measurement on isokinetic dynamometer
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Injury
Evaluation of the Effect of Using WeChat Applet to Intervene in the Home Functional Exercise of Patients After Anterior Cruciate Ligament Reconstruction Based on the Health Belief Model
Based on the home rehabilitation exercise of patients undergoing ACL reconstruction, the existing WeChat applet of sports medicine of the Third Hospital of Beijing Medical University is optimized to be used as a health education…
- Trial name
- NCT04957810
- Testing
- WeChat Mini Program
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Tele-rehabilitation, Anterior Cruciate Ligament Reconstruction
Tele-rehabilitation After Anterior Cruciate Ligament Reconstruction
The investigators aims to evaluate the effect of multicomponent supervised tele-rehabilitation, compared to home-based self-rehabilitation, on range of motion (ROM), pain, muscle strength, and function in patients following ACLR.
- Trial name
- tele-rehab (NCT06232824)
- Testing
- Tele-rehabilitation
- Volunteers
- 110 people
- Sponsor
- Kexin Wang, MM
ACL Injury
Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study
It is estimated that 48 out of 10,000 people, in the United States, will tear their anterior cruciate ligament (ACL) annually and undergo ACL reconstruction (ACLR).
- Trial name
- NCT04958733
- Testing
- Autologous bone grafting, Absence of autologous bone grafting
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Hartford Hospital
Anterior Cruciate Ligament Injury
Preemptive Analgesia in Cruciate Reconstruction
The aims of this study was to compare analgesic efficacy of preoperative administration of etoricoxib versus celecoxib for post-operative pain relief after arthroscopic anterior cruciate ligament reconstruction.
- Trial name
- NCT01017380
- Testing
- Celecoxib, etoricoxib
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University
Anterior Cruciate Ligament Tear
Evaluation of Biocleanse Allografts For ACL Reconstruction
The purpose of this study is to determine the efficacy of patellar tendon allografts that have undergone the BioCleanse™ process.
- Trial name
- NCT00187876
- Testing
- ACL reconstruction control, ACL Biocleanse, surgical
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Florida
Anterior Cruciate Ligament (Acl) Reconstruction
The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction surgery is a common procedure performed by orthopedic surgeons. Postoperatively, patients often experience pain, muscle tension, and concerns about their ability to return to…
- Trial name
- NCT06382324
- Testing
- mindfulness practice of body scan, listening to light music
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Anterior Cruciate Ligament Injuries, Atrophy, Muscular
Bilateral Versus Unilateral Strength Training After ACLR
After rehabilitation completion, there remains large deficiencies between the operative (OP) and non-operative (NOP) limbs in lower-limb outcomes (e.g., size, strength, and function) and these deficits can persist for years.
- Conditions
- Anterior Cruciate Ligament Injuries, Atrophy, Muscular, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- BUST (NCT06032247)
- Testing
- Resistance exercise program- UL, Resistance exercise program- BL
- Where
- United States
- Sponsor
- University of Kansas