Clinical trials: ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Anterior Cruciate Ligament Injury, Knee Injuries
Bone Tunnel Widening Following ACL Reconstruction
Hypothesis 1: There is less tunnel-widening with bone-patella tendon-bone graft compared with the hamstring graft when the same fixation method is used.
- Trial name
- NCT00198042
- Testing
- Surgical reconstruction of the ACL
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
ACL Injury, Knee Injuries
Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of…
- Conditions
- ACL Injury, Knee Injuries, Muscle Weakness
- Trial name
- PREDICT-ACLv2 (NCT05897970)
- Testing
- Return-to-sport (RTS) follow-up
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Reconstruction, Medial Patellofemoral Ligament Reconstruction
Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees
The goal of this pilot clinical trial is to compare anterior femoral cutaneous nerve block (AFCN) to adductor canal block ACB) for pediatric patients undergoing either anterior cruciate ligament (ACL) or medial patellofemoral…
- Trial name
- NCT06590402
- Testing
- Bupivacaine, Dexamethasone in Adductor Canal Block, Bupivacaine, Dexamethasone in Anterior Femoral Cutaneous Nerve Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Injury, Knee Injury
Anterior Cruciate Ligament (ACL) Tunnel Widening Comparing All-inside and Interference Screw Fixation Technique
The purpose of this study is to evaluate the incidence and degree of bone tunnel widening between two groups who have undergone anterior cruciate ligament reconstructive surgery.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, ACL Injury
- Trial name
- NCT02052856
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Exploring Prolonged AMR in ACL Reconstructed Patients
The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, ACL
- Trial name
- NCT06430775
- Where
- Belgium
- Volunteers
- 190 people
- Sponsor
- University Ghent
Anterior Cruciate Ligament Reconstruction
Intraarticular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction
Post-anterior cruciate ligament reconstruction (ACLR) hemarthrosis may result in increased pain thus delaying postoperative rehabilitation, which may eventually lead to arthrofibrosis and a functional deficit.
- Trial name
- NCT03580018
- Testing
- Tranexamic Acid Powder, Post-anterior cruciate ligament reconstruction (ACLR)
- Where
- Taiwan
- Volunteers
- 320 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anterior Cruciate Ligament (ACL) Reconstruction, Preoperative Rehabilitation
VR-Based Preoperative Rehabilitation Program for Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction
Between April 2, 2024, and October 1, 2024, a study will be conducted at the Department of Orthopedics in the First Affiliated Hospital of Shantou University Medical College involving 120 patients who will undergo anterior…
- Trial name
- NCT06347523
- Testing
- The VR-based preoperative rehabilitation program;, standard nursing care,
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Shantou University Medical College
Ligament; Laxity, Knee, Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament-reconstruction: Quadriceps Tendon or Hamstrings Tendon? A Prospective Trial
The purpose of this study is to determine whether there is a difference in muscle strength after anterior cruciate ligament comparing 2 surgery technics. Using either autograft hamstrings tendon or a autograft quadriceps tendon.
- Trial name
- NCT02173483
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00738010)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Analysis Of Knee Joint Of Patients With Anterior Cruciate Ligament Injury Undergoing Physiotherapy After Two Different Surgical Techniques: A Randomized Clinical Trial.
The objetive is compare knee joint stability, functional capacity, postural control, activation, and muscle strength of patients undergoing conventional Anterior Cruciate Ligament Reconstruction or the conventional Anterior…
- Trial name
- NCT06809920
- Testing
- Group 1 ACL reconstruction with quadruple flexor tendons and conventional physiotherapy, Group 2 ACL reconstruction with quadruple flexor tendons + ALL reconstruction
- Where
- 2 sites in Brazil
- Volunteers
- 26 people
- Sponsor
- Universidade Estadual de Londrina
Anterior Cruciate Ligament Reconstruction, Hydrotherapy
The Effect of Aquatic Rehabilitation on Knee Function in Anterior Cruciate Ligament Reconstruction Patients.
The goal of this clinical trial is to compare the applicability and effectiveness of an aquatic rehabilitation training program with a conventional land-based rehabilitation program in terms of lower extremity biomechanics and…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Hydrotherapy, Gait, Muscle Function
- Trial name
- NCT05929118
- Testing
- Aquatic Rehabilitation, Land-based Rehabilitation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Sport University
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Physical Activity, Knee Joint Loading and Joint Health
The purpose of this study is to investigate the association between time spent in moderate to vigorous physical activity and markers of cartilage metabolism in the years following anterior cruciate ligament reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Post-traumatic Osteoarthritis
- Trial name
- NCT05306054
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Bath
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Anterior Cruciate Ligament Rupture
Tolerance, Efficacy, revAlidation, Myostim
Evaluation of efficacy and tolerance of a food supplement (MYOSTIM®) versus a placebo in postoperative revalidation of patients after reconstructive surgery of anterior cruciate ligament.
- Trial name
- NCT04684771
- Testing
- MYOSTIM®
- Where
- 2 sites in Belgium
- Volunteers
- 35 people
- Sponsor
- Alternativa International S.A
Rupture of Anterior Cruciate Ligament
Study of the Anatomical Direct Insertion Anterior Cruciate Ligament Reconstruction
The purpose of the study is to study the effect of anatomical direct insertion ACL reconstruction compared with conventional anatomical ACL reconstruction.
- Trial name
- NCT02833454
- Testing
- direct insertion anterior cruciate ligament reconstruction, single bundle anterior cruciate ligament reconstruction, double bundle anterior cruciate ligament reconstruction
- Volunteers
- 320 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament
Evaluation of Outpatient Surgery in the Anterior Cruciate Ligament Reconstructions With Hamstring Hospital
Care in ambulatory surgery (CA) is growing in France, despite lagging behind other countries in North or US Europe. Arthroscopic knee surgery is a minimally invasive surgery eligible for CA.
- Trial name
- DIDTGENOU (NCT02895607)
- Testing
- Ambulatory care among eligible patients
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Anterior Cruciate Ligament Reconstruction
interACTION: A Portable Joint Function Monitoring and Training System to Supplement Home Exercise Programs Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to ascertain if home-based therapy with monitoring via telemedicine can overcome many barriers to compliance and improve rehabilitation following ACL reconstruction.
- Trial name
- NCT02775188
- Testing
- interACTION, Standard of Care Physical Therapy
- Where
- United States
- Sponsor
- University of Pittsburgh
ACL - Anterior Cruciate Ligament Rupture
Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is the major treatment option for ACL injuries. Despite this, recurrence rates are high.
- Trial name
- NEURO-K-STARTS (NCT07659613)
- Testing
- NEURO-K-STARTS
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche