Clinical trials: ARDS: Acute Respiratory Distress Syndrome
Severe Acute Respiratory Syndrome Coronavirus 2
Vagus Nerve Stimulation ARDS Prevention Trial for COVID-19 Hospitalized Patients
This trial is designed to determine if the inflammation modulating effect of vagus nerve stimulation can improve pulmonary function and limit progression to ARDS in hospitalized COVID-19 hospitalized patients.
- Trial name
- NCT04379037
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Nemechek Technologies
COVID - 19, Acute Respiratory Distress Syndrome (ARDS)
Prone Duration in COVID-19 ARDS
The aim of this observational study is to learn the effects of prone position duration on patient outcomes in patients with severe acute respiratory distress syndrome (ARDS) due to Coronavirus Disease - 2019 (COVID-19).
- Trial name
- PRODUR-CARDS (NCT06765759)
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- Istanbul University - Cerrahpasa
Sever Chest Trauma, Mechanical Ventilation
Driving Pressure in Trauma
Traumatic chest injuries are responsible for significant morbidity and the cause of trauma-related death in 20%-25% of cases. Thoracic trauma can include multiple injuries, mainly osseous (ribs, sternal fractures, flail chest)…
- Trial name
- NCT03367442
- Testing
- no intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Acute Lung Injury, Acute Respiratory Distress Syndrome
Epidemiology Research on Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) in Adult ICU in Shanghai
To survey the prevalence and the mortality of the Acute Lung Injury/ Acute Respiratory Distress Syndrome (ALI/ARDS) in 12 university hospital ICUs in Shanghai.
- Trial name
- NCT01186874
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji University
ARDS, Prevention and Control
A Combination of an Inhaled Budesonide and Ipratropium in Patients at Risk of Developing ARDS
Acute respiratory distress syndrome (ARDS) is a severe lung condition with high morbidity and mortality, despite advances in medical care.
- Trial name
- BUDIPRA-ARDS (NCT06657079)
- Testing
- combined standard aerosolized doses of budesonide (0.5 mg/2 mL) every 12 hours and ipratropium bromide (500/2 mL) every eight hours for up to five days
- Where
- Egypt
- Volunteers
- 119 people
- Sponsor
- Damanhour University
ARDS, Acute Respiratory Distress Syndrome
Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients
The SARS-CoV2 pandemic and resulting COVID-19 infection has led to a large increase in the number of patients with acute respiratory distress syndrome (ARDS).
- Conditions
- ARDS, Acute Respiratory Distress Syndrome, Covid19, Endothelial Dysfunction
- Trial name
- INVENT COVID (NCT04794088)
- Testing
- Imatinib Mesylate intravenous solution
- Where
- 2 sites in Netherlands
- Volunteers
- 67 people
- Sponsor
- Dr. Jurjan Aman
COVID-19, Mechanical Ventilation
Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome
This multicentric prospective clinical practice study aims at evaluating clinical factors associated with a prolonged invasive mechanical ventilation and other outcomes such as mortality and ICU length of stay in patients…
- Conditions
- COVID-19, Mechanical Ventilation, Quality of Life, Radiologic Increased Density of Lung
- Trial name
- NCT04411459
- Testing
- Invasive mechanical ventilation
- Where
- 20 sites in Italy
- Volunteers
- 470 people
- Sponsor
- Azienda Usl di Bologna
COVID-19 Acute Respiratory Distress Syndrome
Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients
In this comparative prospective study, we aim to compare the classic Macintosh laryngoscope and the Mac Grath videolaryncoscope in ICU covid 19 patients recruiting intubation and invasive mechanical ventilation.
- Trial name
- NCT04956913
- Testing
- Mac Grath, Macintosh
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Infection With Coronavirus SARS-CoV2
Long Term Physical Functional Limitations in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation
Infection with coronavirus SARS-CoV2 (COVID-19 disease) is unique with its speed of propagation, structural medical reorganizations and length of stay in intensive care needed, diversity of the affected population (in particular…
- Trial name
- CAPACoV19 (NCT04356378)
- Testing
- Data record
- Where
- France
- Volunteers
- 149 people
- Sponsor
- CHU de Reims
Acute Respiratory Distress Syndrome, Severe Acute Respiratory Syndrome
Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS
Background: Intra-alveolar clotting and alveolar collapse in ARDS is due to alveolar capillaries epithelial and leakage. Subsequently, collapse induces hypoxemia that is resistant to recruitment (RM).
- Trial name
- NCT03465085
- Testing
- Unfractionated heparin, Streptokinase
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Acute Respiratory Distress Syndrome
Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain)
The objective is determine the strain measured at the bedside could be a dynamic prognostic marker of during Acute respiratory Distress Syndrome (ARDS).
- Trial name
- AMIS (NCT02003326)
- Testing
- Inflammatory markers
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Coronavirus Infection, Acute Respiratory Distress Syndrome
Pilot Study on Cytokine Filtration in COVID-19 ARDS
Background: There are no proven therapies for COVID-19 infection. COVID-19 infects the respiratory epithelium of the lower airways, causing widespread damage via cytopathic effects, resulting in severe inflammation and…
- Conditions
- Coronavirus Infection, Acute Respiratory Distress Syndrome, COVID
- Trial name
- CytokCOVID19 (NCT04361526)
- Testing
- Cytokine Adsorption
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Manuel Castellà
ARDS Secondary to COVID-19 Pneumonia
CACOLAC : Citrulline Administration in the Hospital Patient in Intensive Care for COVID-19 Acute Respiratory Distress Syndrome
Respiratory involvement of SARS-CoV2 leads to acute respiratory distress syndrome (ARDS) and significant immunosuppression (lymphopenia) exposing patients to long ventilation duration and late mortality linked to the acquisition…
- Trial name
- CACOLAC (NCT04404426)
- Testing
- L-citrulline
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Rennes University Hospital
Acute Respiratory Distress Syndrome, Cardiogenic Shock
Closed Loop Mechanical Ventilation and ECMO
Mechanical ventilation and ECMO are both technologies interacting on gas exchange. Nevertheless, besides a consensus paper, no evidence-based guidelines regarding protective lung ventilation on ECMO exist to date.
- Trial name
- NCT04925518
- Testing
- Closed Loop Mechanical Ventilation, Conventional Mechanical Ventilation
- Volunteers
- 62 people
- Sponsor
- University of Zurich
COVID-19, SARS CoV 2 Virus
Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine
The primary objective of this effort will be to optimize and operationalize innovative passive surveillance systems and in parallel, the effort will identify, evaluate, and transition groundbreaking new technologies in…
- Conditions
- COVID-19, SARS CoV 2 Virus, COVID-19 Pneumonia, COVID-19 Respiratory Infection
- Trial name
- COVID-19 (NCT06402318)
- Testing
- A&M Breathalyzer PROTECT Kiosk
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Geneva Foundation
Acute Respiratory Distress Syndrome, Ards
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Non-COVID-19 Acute Respiratory Distress Syndrome
This is a Phase 2 randomized study to assess the safety and efficacy of COVI-MSC in the setting of current standard of care treatments for subjects hospitalized subjects with acute respiratory distress syndrome not related to…
- Trial name
- NCT04909879
- Testing
- COVI-MSC
- Sponsor
- Sorrento Therapeutics, Inc.
Respiratory Distress Syndrome, Preterm Birth
Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)
In preterm infants with neonatal respiratory distress syndrome (NRDS), exogenous pulmonary surfactant(PS) replacement therapy is one of the most important therapeutic breakthrough to reduce neonatal mortality.
- Conditions
- Respiratory Distress Syndrome, Preterm Birth, Acute Respiratory Distress Syndrome, Surfactant Dysfunction
- Trial name
- NCT04777760
- Testing
- one dose of surfactant replacement, two and more doses of surfactant replacement
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
COVID-19 Acute Respiratory Distress Syndrome
Telerehabilitation Program and Detraining in Patients With Post-COVID-19 Sequelae
The primary objective of this study is to evaluate the effects of a 15-week home telerehabilitation program and a detraining period on cardiorespiratory fitness and muscular efficiency in patients with post-COVID-19 sequelae…
- Trial name
- NCT05866224
- Testing
- Telerehabilitation program
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
COVID, Corona Virus Infection
hCT-MSCs for COVID19 ARDS
This is a 50 patient, Phase 1/2a multi-center pilot study to test the safety and to describe the preliminary efficacy of intravenous administration of allogenic human cord tissue mesenchymal stromal cells (hCT-MSC) as an…
- Conditions
- COVID, Corona Virus Infection, COVID19
- Trial name
- NCT04399889
- Testing
- Human cord tissue mesenchymal stromal cells (hCT-MSC) manufactured by Duke University.
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Joanne Kurtzberg, MD
Conscious Sedation, Pathologic Processes
Prospective Electroencephalography Evaluation of Sedation in COVID-19
Sedation of severe COVID-19 disease are often complicated. We try to find a correlate for this observation by encephalographic studies.
- Conditions
- Conscious Sedation, Pathologic Processes, Electroencephalogram, Acute Respiratory Distress Syndrome
- Trial name
- NCT04815109
- Testing
- Encephalography measurement
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Goethe University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.