Clinical trials: ARDS: Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome ARDS
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is associated with high mortality, some of which can be attributed to ventilator-induced lung injury (VILI) when artificial ventilation is not customized to the severity of lung injury.
- Trial name
- DRIVENT (NCT06322758)
- Testing
- Tidal volume customization in the acute respiratory distress syndrome
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Respiratory Distress Syndrome (ARDS), Acute Hypoxemic Respiratory Failure
Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure
Acute hypoxemic respiratory failure may progress to acute respiratory distress syndrome, a life-threatening condition that often requires mechanical ventilation.
- Trial name
- SVALBARD (NCT07463885)
- Testing
- Spontaneous Ventilation Strategy, Controlled Ventilation Strategy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Acute Lung Injury, Acute Respiratory Distress Syndrome
Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Acute Lung Injury
Phase I-II Clinical Trial - Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with Acute Lung Injury ,open label, controlled prospective study.
- Trial name
- UCMSC-ALI (NCT02444455)
- Testing
- UCMSC group
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Acute Respiratory Distress Syndrome, Pneumonia
Inhaled GM-CSF for Respiratory Virus-Associated Severe Pneumonia
This study will investigate the safety and efficacy of the administration of inhaled GM-CSF to patients with respiratory virus-associated pneumonia.
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia, Respiratory Virus Infection
- Trial name
- iGRASP (NCT02601365)
- Testing
- Sargramostim 0.04 mcg/kg/dose, Sargramostim 0.2mcg/kg/dose, Sargramostim 1 mcg/kg/dose
- Sponsor
- Milton S. Hershey Medical Center
Respiratory Distress Syndrome, Adult
Drug Study of Albuterol to Treat Acute Lung Injury
Acute Respiratory Distress Syndrome (ARDS) and a lesser condition that occurs prior to ARDS, Acute Lung Injury (ALI), are medical conditions that occur when there is severe inflammation and increased fluids (edema) in both lungs…
- Trial name
- ALTA (NCT00434993)
- Testing
- Albuterol Sulfate, Mini-Bronchoalveolar Lavage (BAL)
- Where
- 40 sites in United States
- Volunteers
- 282 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
ARDS
Extracorporeal Membrane Oxygenation (ECMO) in Non-intubated Patients With Acute Respiratory Distress Syndrome (ARDS)
Proof-of-concept study addressing the feasibility of awake ECMO (v/v) in patients with acute respiratory failure
- Trial name
- NCT01669863
- Testing
- ECMO, ECMO in non-intubated patients
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Hannover Medical School
Infection With Coronavirus SARS-CoV2
Long Term Physical Functional Limitations in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation
Infection with coronavirus SARS-CoV2 (COVID-19 disease) is unique with its speed of propagation, structural medical reorganizations and length of stay in intensive care needed, diversity of the affected population (in particular…
- Trial name
- CAPACoV19 (NCT04356378)
- Testing
- Data record
- Where
- France
- Volunteers
- 149 people
- Sponsor
- CHU de Reims
ARDS (Acute Respiratory Distress Syndrome), VV ECMO
Trial of Total Lung Protective Ventilation in Adult VV-ECMO Patients With Severe ARDS
The purpose of this study is to find a better way to protect the lungs of patients with Acute Respiratory Distress Syndrome (ARDS) who are being treated with a mechanical ventilator in addition to an extracorporeal membrane…
- Trial name
- PROTECT-ARDS (NCT07790133)
- Testing
- Mechanical Power Targeted Ventilation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Acute Respiratory Distress Syndrome, COVID-19 Pneumonia
Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19
Respiratory failure associated with Covid-19 can be expressed as acute respiratory distress syndrome (ARDS), which is an acute inflammatory lung injury,which generally requires the use of invasive mechanical ventilation (MV).
- Conditions
- Acute Respiratory Distress Syndrome, COVID-19 Pneumonia, Recruitment
- Trial name
- NCT05248243
- Testing
- Recruitment assessment
- Where
- Argentina
- Volunteers
- 41 people
- Sponsor
- Ramos Mejía Hospital
ARDS, NRDS
Acute Respiratory Distress Syndrome(ARDS) in Neonates
Acute respiratory distress syndrome in neonates has been defined in 2015. Earlier identification and successful intervention into the potential pregnancy associated risk factors for the conversion from NRDS to ARDS is one of the…
- Trial name
- NCT03227289
- Testing
- Stayed in NRDS, Converted to ARDS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Acute Respiratory Distress Syndrome
Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is a clinical syndrome caused by intrapulmonary and/or extrapulmonary causes, characterized by intractable hypoxemia.
- Trial name
- NCT06013319
- Testing
- Esmolol
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Zhiming Jiang
Acute Respiratory Distress Syndrome
Impact of Tissue Plasminogen Activator (tPA) Treatment for an Atypical Acute Respiratory Distress Syndrome (COVID-19)
At the beginning COVID-associated lung injury was considered as typical ARDS, hence respiratory and nonrespiratory treatments were delivered according to general principles for this kind of illness.
- Trial name
- AtTAC (NCT04453371)
- Testing
- Tissue plasminogen activator, Ringer solution
- Sponsor
- Negovsky Reanimatology Research Institute
Sars-CoV2, Acute Respiratory Distress Syndrome
Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease)
*At this time, we are only enrolling at Houston Methodist Hospital (HMH)/Baylor College of Medicine (BCM) and are not shipping cells outside of BCM/HMH.* This is a study for patients who have respiratory infection caused by…
- Conditions
- Sars-CoV2, Acute Respiratory Distress Syndrome, COVID-19
- Trial name
- NCT04345601
- Testing
- Mesenchymal Stromal Cells, Supportive Care
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Baylor College of Medicine
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
This is a phase I trial followed by a phase II randomized trial. The purpose of phase I study is the feasibility of treating patients with acute respiratory distress syndrome (ARDS) related to COVID-19 infection (COVID-19) with…
- Conditions
- COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04565665
- Testing
- Best Practice, Mesenchymal Stem Cell
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Morality, Oxygenation Indices
We Compared the Covid-19 Acute Respiratory Distress Syndrome (ARDS) Patients Who Applied Prone Positioning for16-24 Hours vs 24-48 Hours
The goal of this study is to understand if there is any improvement on oxygenation of patients diagnosed with Covid-19 ARDS patients when we extend the duration of prone positioning.
- Conditions
- Morality, Oxygenation Indices, Hypoxia
- Trial name
- NCT06530095
- Testing
- prone positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Acute Respiratory Distress Syndrome
Thorathic Fluid Content as an Early Predictor of Weaning From Mechanical Ventilation in Acute Respiratory Distress Syndrome
Thorathic fluid content measurement using indirect cardiometry is required for prediction of Weaning from mechanical ventilation in cases of acute respiratory distress syndrome and its value in sucsess Weaning
- Trial name
- NCT06233448
- Testing
- Indirect cardiometry
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Acute Respiratory Distress Syndrome, Adrenal Insufficiency
Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS)
The purpose of this study is to see if stress doses of hydrocortisone improve early outcome in patients who are in early stage of ARDS and with relative adrenal insufficiency.
- Trial name
- NCT00773058
- Testing
- hydrocortisone
- Volunteers
- 100 people
- Sponsor
- Southeast University, China
Acute Respiratory Distress Syndrome
Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs
The acute respiratory distress syndrome(ARDS)has a high morbidity and mortality in patients admitted to intensive care units(ICUs). It represents a significant public health issue.
- Trial name
- NCT02490215
- Where
- 26 sites in China
- Volunteers
- 2,530 people
- Sponsor
- Peking Union Medical College Hospital
Respiratory Distress Syndrome (RDS)
Components of Mechanical Power on the Functional Lung in ARDS
Mechanical power (MP) is a composite variable that integrates static and dynamic respiratory parameters and has been associated with ventilator-induced lung injury (VILI).
- Trial name
- NCT07171632
- Testing
- monitoring of clinical and ventilatory variables
- Volunteers
- 184 people
- Sponsor
- Ramos Mejía Hospital
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