Clinical trials: ART, open to volunteers
Pediatric
Posıtıve Psychology-Based Art Therapy In Hospıtalızed Chıldren
Pediatric hospitalization is known to be associated with negative developmental and psychosocial outcomes for child patients. Art therapy is a way to directly address the emotional world of hospitalized children.
- Trial name
- PP-ArtChild (NCT07735364)
- Testing
- Posıtıve Psychology-Based Art Therapy In Hospıtalızed Chıldren (PP-ArtChild)+Routine Pediatric Nursing Care, Routine Pediatric Nursing Care
- Volunteers
- 80 people
- Sponsor
- Suleyman Demirel University
Oropharynx Cancer, Radiotherapy; Complications
Adaptive RadioTherapy for OroPharynx Cancer
This is a phase II randomized trial, where patients with histologically proven squamous cell carcinoma of oropharynx that have primary tumor (T3 - T4) in place, treated with curative intent chemoradiation, will be randomized to…
- Conditions
- Oropharynx Cancer, Radiotherapy; Complications, Radiotherapy Side Effect, Dysphagia
- Trial name
- ART-OPC (NCT04901234)
- Testing
- Standard radiotherapy +/- chemotherapy, Experimental radiotherapy +/- chemotherapy
- Where
- 2 sites in Australia, Canada
- Volunteers
- 120 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Health Related
Newborns From Patients Treated With ART (Assisted Reproductive Technology)
The Prospective Cohort Study for Newborns from patients treated with ART was set up to investigate the short- and long-term health consequences in Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University…
- Trial name
- NCT03993158
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Healthy
Medical Illustration Design Characteristic Evaluation
The goal of this study is to understand what people understand from medical illustrations, and what meaning and emotions (such as anxiety) they derive from different design elements.
- Trial name
- NCT06435806
- Testing
- Medical Illustration design
- Where
- 2 sites in United States
- Volunteers
- 8,200 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Advanced HIV Disease
Advanced HIV Disease During the First Six Months on Antiretroviral Therapy in Zambia
In Zambia, an estimated 20% of HIV-positive clients continue to present for first-time antiretroviral therapy (ART) initiation or re-initiation with advanced HIV disease (AHD).
- Trial name
- AHD-Zambia (NCT06904456)
- Where
- Zambia
- Volunteers
- 11,800 people
- Sponsor
- Boston University
Cryptococcal Antigenemia, HIV-1-infection
Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers
This randomized clinical trial will evaluate the optimal duration of fluconazole therapy and timing of antiretroviral therapy initiation among HIV-infected persons with asymptomatic cryptococcal antigenemia and low cryptococcal…
- Conditions
- Cryptococcal Antigenemia, HIV-1-infection, Cryptococcal Infection, Cryptococcal Meningitis
- Trial name
- NCT07743593
- Testing
- Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole
- Where
- Uganda
- Volunteers
- 505 people
- Sponsor
- University of Minnesota
Eco-anxiety, Psychological Distress
The Impact of an Art and Philosophy-based Intervention on Children's Eco-anxiety
Objective: To examine the impact of climate change on children's mental health by comparing the effectiveness of an arts only intervention (ABI) and an arts and philosophy-based intervention (APBI) on children's eco-anxiety…
- Conditions
- Eco-anxiety, Psychological Distress, Tolerance to Distress, Hope
- Trial name
- NCT06937021
- Testing
- Art and philosophy intervention (APBI), Art based intervention (ABI)
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bishop's University
IVF, Infertility
What To-be-discard Biomaterials From ART Cycles Can Tell us About the Treatment Cycle Outcome?
Various to-be-discard material from IVF treatment cycle will be collect and examined, aiming to identify potential reasons of successful outcome or cycle failure.
- Trial name
- NCT06021340
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Fertility Preservation, Cancer Remission
Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology
Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity. Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.
- Conditions
- Fertility Preservation, Cancer Remission, Reproductive Outcomes, Reproductive Health
- Trial name
- FERT-ISSUES (NCT07312058)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
HIV - Human Immunodeficiency Virus, Obesity
DOR/TDF/3TC COmpared With BIC/FTC/TAF in ART-Naïve People Living With HIV and Overweight or Obesity
Background:Historically, HIV infection was associated with significant weight loss. However, weight gain is now commonly observed after initiating antiretroviral therapy (ART), particularly in individuals underweight at baseline.
- Conditions
- HIV - Human Immunodeficiency Virus, Obesity, Overweight and/or Obesity
- Trial name
- COATL (NCT07075146)
- Testing
- DOR/3TC/TDF, BIC/FTC/TAF
- Where
- Mexico
- Volunteers
- 306 people
- Sponsor
- José Antonio Mata Marín
Psychologic Resilience
Influence of Art Workshops and Cognitive Support for Families of Children With Cancer.
This clinical trial aims to evaluate the effectiveness of combining art workshops and knowledge-based lectures in enhancing psychological resilience among parents of children with cancer, with the primary outcome focused on…
- Trial name
- NCT07878078
- Testing
- Art Workshops and Cognitive Support Sessions.
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Stage II/III Colon Cancer, Bowel Cancer
Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal Cancer
TThis study evaluates the safety and effectiveness of pre-operative artesunate, given orally once a day for 14 days prior to surgery, in patients with Stage II/III colorectal cancer.
- Trial name
- NeoART-M (NCT07095309)
- Testing
- Artesunate
- Where
- 6 sites in Malaysia
- Volunteers
- 120 people
- Sponsor
- Metanoic Health Ltd.
HIV, HIV Antiretroviral Therapy (ART) Adherence
Selection of Resistant Mutations to Dolutegravir in PLWH Treated in Mozambique
The HIV infection not fully controlled, despite being under antiretroviral treatment, could make virus resistance against the antiretroviral treatments, making hardest the well control of HIV infection.
- Trial name
- REDOCH (NCT06607588)
- Testing
- Not applicable- observational study
- Where
- Mozambique
- Volunteers
- 200 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Cervical Cancer, Endometrial Cancer
MH-ART vs CF-IMRT in Postoperative Cervical/Endometrial Cancer
This is an investigator-initiated, prospective, national multi-center, phase III, randomized, open-label, non-inferiority clinical study.
- Trial name
- ARTISAN (NCT07584161)
- Testing
- Moderately fractionated radiotherapy using online adaptive radiotherapy technology, Conventionally fractionated radiotherapy using image-guided intensity-modulated radiotherapy technology.
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Xiaorong Hou
HIV-1-infection
Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch
Combination antiretroviral therapy (cART) HIV treatments are associated with increased quality of life, and a normalisation of life expectancy in people living with HIV.
- Trial name
- DORDOL (NCT04892654)
- Testing
- Doravirine, Dolutegravir, Triple cART regimen
- Where
- 3 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Metabolic Syndrome, Obesity & Overweight
Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy
We investigate the role of empagliflozin in the treatment of obesity in PLWH.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07336797
- Testing
- Empagliflozin (oral)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Abdelrahman Mahmoud
Brain Injuries
Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)
To study the feasibility of the various model of ART rental service for home use, prescribed and supervised by experienced rehabilitation professionals and supported by tech partners, and its efficacy in improving function in…
- Trial name
- R@H (NCT07904624)
- Testing
- ART
- Where
- 3 sites in Singapore
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
HIV-1-infection, Opioid Use Disorder
Evaluation of Switch to Dolutegravir/Lamivudine (DTG/3TC) From Current Suppressive Antiretroviral Therapy in People Living With HIV (PLWH) Receiving Opioid Agonist Therapy (OAT)
The goal of this clinical trial is to determine the efficacy of Dolutegravir/Lamivudine (DTG/3TC), or "Dovato", in virally-suppressed (HIV-1 RNA < 200 copies/mL) individuals receiving opioid agonist therapy such as methadone…
- Trial name
- NCT06580873
- Testing
- DOVATO
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
HIV
Interleukin-15 to Promote Post-ART Control of HIV
Even though HIV medicine stops the virus from making more copies of itself, the virus remains in the body by hiding inside of immune cells.
- Trial name
- INTERRUPT-HIV (NCT07145164)
- Testing
- N-803
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Michael Peluso, MD
HIV-1-infection
Doravirine/Lamivudine (DOR/3TC) as a Maintenance ART in Comparison With Dolutegravir/Lamivudine (DTG/3TC) in PLWH Successfully
The main objective of the MODULO trial is to compare (non-inferiority) the capacity of DOR/3TC and DTG/3TC two-drug regimens of maintain virological success at W48 in people living with HIV virus ( PLWH) with suppressed HIV…
- Trial name
- MODULO (NCT06774872)
- Testing
- Doravirine 100Mg Tab and Lamivudine 300 Mg Tab, Dolutegravir 50mg Tab and Lamivudine 300 Mg Tab
- Where
- France
- Volunteers
- 408 people
- Sponsor
- Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida