Clinical trials: ART
Pharmacogenetics, HIV
Individualized Antiretroviral Therapy
The efficacy and safety of antiretroviral therapy and the damage caused by chronic inflammation in the presence of the virus has recently lead to the consideration of initiating antiretroviral therapy earlier than what is…
- Conditions
- Pharmacogenetics, HIV, Drug Monitoring
- Trial name
- IAT (NCT03385473)
- Testing
- Pharmacogenomic index, Therapeutic drug monitoring
- Where
- Argentina
- Volunteers
- 190 people
- Sponsor
- Hospital Italiano de Buenos Aires
HIV Infections
Collection of Blood Samples From SMART Study Participants for Future Genetic Studies
The purpose of this study is to collect blood samples from SMART study participants to use in future genetic studies.
- Trial name
- NCT00377169
- Where
- 42 sites in United States, American Samoa and 14 more
- Volunteers
- 3,261 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Personality Disorders
The Effectiveness of a Creative Arts en Psychomotor Therapy Intervention for People With Personality Disorders. From Negative Thinking to Positive Acting.
Mental health consists of the absence of mental disorders and the presence of mental well-being. However; mental health care currently focuses mainly on mental disorders and less on promoting mental well-being.
- Trial name
- NDPD (NCT06219122)
- Testing
- Creative arts and psychomotor therapies intervention for people with personality disorders
- Where
- Netherlands
- Volunteers
- 37 people
- Sponsor
- Suzanne Haeyen
Hiv, Adherence, Medication
Making ART Work Among Brazilian Youth
This study seeks to develop and pilot test a theory-based, integrated technology and counseling intervention to improve ART adherence among sexual and gender minority (SGM) young people living with HIV (ages 18-24) in Rio de…
- Trial name
- NCT06056037
- Testing
- Experimental: Making ART Work, Standard of Care
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Brown University
Infertility
Observational Post-Authorisation Study on the Use of Bemfola® in Human Assisted Reproductive Techniques in Spain.
Non-comparative, observational, ambispective post-authorisation study (EPA-SP).
- Trial name
- BIRTH (NCT02941341)
- Testing
- r-hFSH
- Where
- Spain
- Volunteers
- 1,222 people
- Sponsor
- Finox AG
HIV Infections
HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV
The purpose of this study is to determine if pregnancy-limited, short-term combination HIV treatment regimens -- which were used solely for the prevention of mother to child transmission of HIV and discontinued postpartum …
- Trial name
- Nearly Naive (NCT00442962)
- Testing
- Efavirenz, Emtricitabine/Tenofovir disoproxil fumarate
- Where
- 9 sites in United States, Brazil and 1 more
- Volunteers
- 54 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV Infections
ART Drug Dosage Adjustment in HIV-infected Population
The purpose of this study is to determine efficacy of the combination of low dose of Tenofovir, Efavirenz and Lamivudine in treating HIV-infection.
- Trial name
- NCT02632474
- Testing
- Tenofovir(TDF)+Lamivudine(3TC)+Efavirenz(EFV)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai Public Health Clinical Center
Anxiety, Depression
Health Benefits of Gardening
The objective of the research is to test the hypothesis that participating in group-based gardening or group-based art activities may alter the mental health and cardiac physiological status of a wellness population of women ages…
- Conditions
- Anxiety, Depression, Healthy, Mood Disturbance
- Trial name
- NCT03266120
- Testing
- Art, Gardening
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Florida
HIV Infection
Impact of Immediate Versus South African Recommendations Guided ART Initiation on HIV Incidence
This trial is evaluating a public health intervention strategy trial which aims to reduce the incidence of HIV at a population-level.
- Trial name
- TasP (NCT01509508)
- Testing
- Immediate ARV treatment initiation with TDF/FTC/EFV, South African recommendation guided ARV (TDF/FTC/EFV) initiation
- Where
- South Africa
- Volunteers
- 28,153 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Art, Wellness, Psychological
The Singapore Art-Health Study
The goal of the Singapore Art-Health RCT is to examine the effect of a standardized 12-week museum -based participatory art program on health condition, well-being, and quality of life in older community dweller, one that adheres…
- Conditions
- Art, Wellness, Psychological, Frailty, Quality of Life
- Trial name
- NCT05945589
- Testing
- Singapore A-Health Intervention
- Where
- Singapore
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
HIV Infection, Carotid Atherosclerosis
Influence of Pravastatin on Carotid Artery Structure and Function in HIV-infected Patients Under Antiretroviral Therapy
The advent of new antiretroviral agents, in particular Highly Active Antiretroviral Therapy (HAART), spectacularly reduced HIV-associated morbidity and mortality.
- Conditions
- HIV Infection, Carotid Atherosclerosis, Dyslipidemia
- Trial name
- NCT00147797
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Saint Antoine University Hospital
HIV-1-infection
Short Cycle Therapy in ART Regimens Containing Rilpivirine: Assessment of Patients' Satisfaction
With this study the investigators propose to evaluate the satisfaction of the patients receiving antiretroviral treatment for HIV infection with standard everyday scheme, compared to patients receiving the same treatment with…
- Trial name
- NCT04281459
- Testing
- HIV Treatment Satisfaction Questionnaire status
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Infertility
A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA)
The purpose of this study is to assess the efficacy and safety of follitropin alfa/lutropin alfa in Japanese participants with Luteinizing hormone (LH) and Follicle stimulating hormone (FSH) deficiency undergoing Assisted…
- Trial name
- NCT07340827
- Testing
- Follitropin alfa/lutropin alfa (MBJ-0011), hMG, Cetrorelix acetate
- Where
- 21 sites in Japan
- Volunteers
- 266 people
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
HIV, HIV Infections
Evaluation of Effectiveness of Pharmaceutical Care on the Adherence of HIV-Positive Patients to Antiretroviral Therapy
INTRODUCTION: Studies prove that the pharmaceutical care (PC) increases the adherence to the antiretroviral; thus, they increase the undetectable viral load.
- Trial name
- PC-HIV (NCT00959361)
- Testing
- pharmaceutical care
- Where
- Brazil
- Volunteers
- 332 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Earthquake Victims
Effects of Expressive Art Therapy Applied to Earthquake Victims Who Have Experienced Loss
Earthquakes can negatively affect individuals' mental health by creating serious traumatic effects on individual and societal levels.
- Trial name
- NCT07010861
- Testing
- Expressive Art Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Merve Kızılırmak Tatu
Human Immunodeficiency Virus (HIV) Infection
Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART
This is a study of HB-502 and HB-501 alternating 2-vector therapy in people living with human immunodeficiency virus (HIV) who are taking antiretroviral treatment (ART).
- Trial name
- NCT06430905
- Testing
- HB-502 and HB-501 alternating 2-vector therapy Dose Level 1, HB-502 and HB-501 alternating 2-vector therapy Dose Level 2
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Hookipa Biotech GmbH
Acute HIV Infection
Empiric Treatment for Acute HIV in the ED
An acceptance and feasibility study for immediate ART initiation and storage of laboratory specimens for individuals with suspected acute HIV infection who are diagnosed in one of the 7 participating emergency rooms
- Trial name
- EMTreatED (NCT03711253)
- Testing
- Bictegravir 50mg+Tenofovir AF 25 mg+emtricitabine 200 mg
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Endometriosis, Deep Endometriosis
Retrospective Analysis of Results of Surgery for Deep Bowel Endometriosis
identification of patients operated becaus of bowel endometriosis at the endometriosis center, University Hospital Muenster, Germany, starting 2009, Analysis of Patient history, surgical procedurie, intraoperative complications…
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Reproductive Issues
- Trial name
- NCT04669769
- Testing
- interview
- Where
- Germany
- Volunteers
- 151 people
- Sponsor
- University Hospital Muenster
HCG; IVF; Pregnancy Rates; ART; Chorionic Gonadotropin
Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART
The objective of this prospective randomized clinical trial is to investigate whether the addition of low-dose hCG to a short GnRH-agonist protocol for IVF and ovarian stimulation with rFSH from the onset of the follicular phase…
- Trial name
- HCG (NCT03423537)
- Testing
- hCG
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
HIV Infections
Dolutegravir and Darunavir Evaluation in Adults Failing Therapy
D²EFT is a randomised, open-label study in HIV-1 infected patients failing first-line antiretroviral therapy (ART). The study compares 2 regimens of second-line ART (dolutegravir and darunavir pharmaco-enhanced with ritonavir and…
- Trial name
- D²EFT (NCT03017872)
- Testing
- NRTIs, Dolutegravir, Darunavir
- Where
- 28 sites in Argentina, Brazil and 12 more
- Volunteers
- 831 people
- Sponsor
- Kirby Institute