Clinical trials: ARTHROPLASTY, REPLACEMENT
Osteoarthritis
JOINTS Study - Joint Replacement Outcome in Inpatient Rehabilitation Facilities and Nursing Treatment Sites
1. What are the characteristics of joint replacement patients (DRGs 209 \& 210) served in IRFs and SNFs? How are they similar or different? 2.
- Trial name
- JOINTS (NCT00499278)
- Testing
- Rehabilitation after joint replacement surgery
- Where
- United States
- Volunteers
- 2,384 people
- Sponsor
- MedStar National Rehabilitation Network
Arthroplasty, Replacement, Hip, Fascia Iliaca Block
Ultrasound Guided Fascia Iliaca Block for Pain Control After Elective Hip Replacement Surgery
The purpose of this study is to determine whether ultrasound guided fascia iliaca blocks performed before surgery help to reduce pain after elective total hip replacements.
- Trial name
- NCT02108847
- Testing
- .2% Ropivacaine, Saline, Fascia Iliaca Block
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Saskatchewan
Total Hip Replacement
Unrestricted Rehabilitation Pathway Following Total Hip Replacement
The purpose of ReHip2 is to explore the impact on function and quality of life in patients following Total Hip Replacement (THR).
- Trial name
- ReHip2 (NCT03833258)
- Testing
- Rehabilitation with no precautions
- Where
- 2 sites in United Kingdom
- Volunteers
- 95 people
- Sponsor
- University of Manchester
Rheumatoid Arthritis, Osteoarthritis
Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement
The purpose of this study is to monitor the performance of a large metal-on-metal bearing from the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery or a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872547
- Testing
- DePuy ASR™ Hip System, DePuy ASR™ XL Head / ASR™ Acetabular Cup System
- Where
- 8 sites in Austria, Czechia and 6 more
- Volunteers
- 329 people
- Sponsor
- DePuy International
Total Knee Replacement Closure, Wound Closure
A Comparative Study of Incision Closure Methods for Total Knee Replacement
The aim of the study is to compare incision closure techniques for total knee replacement using a combination of state-of-the-art sutures with tissue adhesives or staples in an effort to identify the best approach with respect to…
- Trial name
- NCT01088074
- Testing
- Histoacryl Tissue Adhesive, Dermabond, Staples
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Foundation for Southwest Orthopedic Research
Arthroplasty, Knee Replacement, Pain, Postoperative
The Effect of Dexamethasone on Pain After Total Knee Replacement Surgery
The purpose of this study is to examine, if a single-dose of dexamethasone given during the operation, alleviates pain after knee replacement surgery.
- Trial name
- NCT03034733
- Testing
- Dexamethasone, Sodium Chloride, (24)NaCl 0,9%
- Where
- Finland
- Volunteers
- 27 people
- Sponsor
- University of Oulu
Osteoarthritis of Knee, Arthroplasties, Knee Replacement
Morbid Obesity and Severe Knee Osteoarthritis - Which Should Be Treated First?
The goal of this study is to determine whether undergoing bariatric surgery before knee replacement leads to better outcomes compared to undergoing knee replacement before bariatric surgery.
- Conditions
- Osteoarthritis of Knee, Arthroplasties, Knee Replacement, Sleeve Gastrectomy
- Trial name
- NCT06767787
- Testing
- laparoscopic sleeve gastrectomy, total knee arthroplasty
- Where
- 2 sites in Canada
- Volunteers
- 142 people
- Sponsor
- Memorial University of Newfoundland
Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
This study aims to analyze the efficacy of intravenous tranexamic acid (TXA) in patients undergoing total hip arthroplasty (THA).
- Conditions
- Blood Loss, Surgical, Tranexamic Acid Adverse Reaction, Hip Replacement
- Trial name
- NCT03019198
- Testing
- Tranexamic Acid Injectable Solution
- Where
- Brazil
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Arthroplasty, Replacement, Knee
Wearable Sensors for Monitoring Recovery After Total Knee Arthroplasty
The goal of this observational study is to investigate the potential of wearable sensors for monitoring the postoperative recovery of patients after TKA.
- Trial name
- NCT05992064
- Testing
- Measuring gait
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aalborg University Hospital
Arthropathy of Hip
Clinical Analysis of Suction Drainage in Cementless Hip Replacement
Randomized prospective study assessing suction drainage in total hip arthroplasty. Group without drainage, 50 hips, compared with group with suction drainage, 50 hips.
- Trial name
- NCT04333264
- Testing
- suction drainage, no suction drainage
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bartosz Paweł
Total Knee Arthroplasty, Post-operative Edema
Manual Lymph Drainage
Manual Lymphatic Drainage (MLD) is a specialized massage technique utilized to decrease various forms of edema. This technique promotes reuptake of interstitial fluid along the pathways of the lymphatic system.
- Trial name
- MLD (NCT02360735)
- Testing
- Manual Lymphatic Drainage, Physical Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Anne Arundel Health System Research Institute
Osteoarthrosis Patients With Total Hip Arthroplasty
Thigh Swelling, Hip-muscle Strength, and Functional Performance Following Total Hip Arthroplasty
By this study the investigators wish to (1) quantify hip strength and functional-performance deficits at discharge after fast-track total hip arthroplasty (THA), and (2) investigate if changes in thigh circumferences, or hip pain…
- Trial name
- THA (NCT01246674)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Hvidovre University Hospital
Hip Joint, Surgery
Muscle Damage of the TFL (Tensor Fascia Latae) During Total Hip Arthroplasty (THA) Through Direct Anterior Approach (DAA)
Direct Anterior Approach (DAA) is known to cause damage to the TFL during the surgical approach, the point of this study is to evaluate the impact between the severity of the per operative TFL damage and the functional short term…
- Conditions
- Hip Joint, Surgery, Arthroplasty, Replacement
- Trial name
- TFL (NCT07360210)
- Testing
- Data collection and self-administered questionnaire
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Bordeaux
Osteo Arthritis Knee, Arthritis Knee
Total Versus Robotic Assisted Unicompartmental Knee Replacement
The purpose of this research is to compare the functional outcomes of patients with end stage medial compartment OA of the knee undergoing a conventional mTKA to those undergoing rUKA and to assess the associated cost economics…
- Conditions
- Osteo Arthritis Knee, Arthritis Knee, Arthropathy of Knee
- Trial name
- TRAKER (NCT05290818)
- Testing
- MAKO™ Partial Knee Arthroplasty, Triathlon (Stryker) Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 159 people
- Sponsor
- NHS Lothian
Knee Osteoarthritis
Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages.
- Trial name
- NCT02033603
- Testing
- Ropivacaine
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Changi General Hospital
Arthroplasty, Replacement
Wound Additives in Primary Total Joint Athroplasty
3 cohorts of total joint patient of 30 members each were randomized to receive PRP or Activated Collegen or no additive were studied for status of the wound at 6 weeks and recorded all complications, infections and reoperations.
- Trial name
- NCT03158623
- Testing
- Platelet Rich Plasma, Cellerate
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salt Lake Orthopedic Clinic
Total Knee Replacement
The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement
Total knee replacement (TKR) is associated postoperatively with considerable pain and analgesic requirement. Total knee replacement is routinely performed under spinal anaesthesia with intrathecal bupivacaine plus preservative…
- Trial name
- NCT01312415
- Testing
- Levobupivacaine, Intrathecal morphine
- Where
- Ireland
- Volunteers
- 42 people
- Sponsor
- Cork University Hospital
Knee Osteoarthritis, Musculoskeletal Disease
Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.
The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving…
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Trial name
- TKACSI (NCT07151417)
- Testing
- PAI, PAI + steroid, PAI + zilretta
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Walter Reed National Military Medical Center
Osteoarthritis
14022 ATTUNE Cementless RP Clinical Performance Evaluation
The primary objective of this study is to examine the change from pre-operative baseline to two year postoperative functional performance improvement for the ATTUNE primary, cementless TKA RP system as measured with the KOOS…
- Trial name
- NCT02839850
- Testing
- Cementless Total Knee Arthroplasty
- Where
- 20 sites in United States, Austria and 7 more
- Volunteers
- 540 people
- Sponsor
- DePuy Orthopaedics
Knee Osteoarthritis
Minimally Invasive Knee Replacement Outcomes (MIKRO) Study
The purpose of this study is to evaluate and compare the clinical, radiographic (x-ray) and cost effectiveness outcomes (cost relative to risks and benefits) of two different minimally invasive knee joint replacement surgical…
- Trial name
- MIKRO (NCT00633113)
- Testing
- MPPA, SV
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Dartmouth-Hitchcock Medical Center