Clinical trials: ATRIAL FLUTTER
Atrial Fibrillation, Atrial Flutter
Anatomical Navigation for Guided Electrophysiology in AFL and AFib
The objective of the study is to collect data on the use of the VERAFEYE Anatomical Guidance System in adult patients indicated to undergo a catheter ablation procedure for the treatment of Atrial Flutter (AFL), paroxysmal AF…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia
- Trial name
- ANGEL-AF (NCT07210151)
- Testing
- VERAFEYE Anatomic Guidance System
- Where
- 4 sites in Croatia, Czechia and 1 more
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Cardiac Arrhythmias, Atrial Fibrillation and Flutter
Increasing Detection of Sub-Clinical Atrial Fibrillation in Defibrillator Patients With the Use of a VDD-ICD Lead
This study aims to compare the Dx-ICD system (experimental) to standard VVI-ICD (control) on the ability to diagnose silent AF in patients without prior AF receiving an ICD for standard indications.
- Conditions
- Cardiac Arrhythmias, Atrial Fibrillation and Flutter, Cardiovascular Diseases, Implantable Cardioverter-Defibrillators
- Trial name
- Dx-AF (NCT03110627)
- Testing
- VDD ICD (experimental group), Single chamber VVI ICD (control group)
- Where
- 9 sites in Canada
- Volunteers
- 188 people
- Sponsor
- Unity Health Toronto
Atrial Fibrillation, Atrial Flutter
Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring
A prospective cohort study to evaluate the association between various triggers encountered in daily life and induction of atrial arrhythmias (atrial fibrillation, atrial flutter, atrial tachycardia and premature atrial…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia, Atrial Tachycardia
- Trial name
- TriggersAF (NCT05526170)
- Testing
- Devices for long-term monitoring of objective and subjective parameters of the body
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Vilnius University
Atrial Fibrillation, Atrial Flutter
A Comparative Study Evaluating the Vein of MArshall Ethanol Infusion Ablation Using an Over-the-wire (OTW) Balloon Versus a microcatHeter in Patients With Atrial Fibrillation
The goal of this study is to compare OTW balloon with microcatheter in the Marshall vein alcohol ablation study. The main questions it aims to answer are: • Is there a difference in the effectiveness and safety of OTW balloon and…
- Trial name
- NCT06460831
- Testing
- Microcatheter, OTW
- Where
- 5 sites in China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation, Atrial Flutter
Engaging Patients to Help Achieve Increased Patient Choice and Engagement for AFib Stroke Prevention
A multi-center, randomized controlled 2-arm trial comparing the effectiveness of an innovative shared decision-making pathway and usual care for Atrial Fibrillation Stroke Prevention
- Conditions
- Atrial Fibrillation, Atrial Flutter, Stroke, Cardiac
- Trial name
- ENHANCE-AF (NCT04096781)
- Testing
- SDMT, Usual Care
- Where
- 5 sites in United States
- Volunteers
- 1,001 people
- Sponsor
- Stanford University
Atrial Fibrillation, Stroke
Electronic Alerts for Stroke Prevention in Patients With Atrial Fibrillation or Atrial Flutter
Atrial fibrillation (AF) is the most preventable cause of stroke. CHADS and CHA2DS2VASc scores predict the likelihood of stroke in patients with nonvalvular AF.
- Trial name
- AF-ALERT (NCT02339493)
- Testing
- Computer Electronic Alert
- Where
- United States
- Volunteers
- 458 people
- Sponsor
- Brigham and Women's Hospital
Atrial Fibrillation (AF), Atrial Flutter
Registry of Atrial Arrhythmia Ablation Procedures Using Pulsed Field Ablation in Poland
The aim of the described project is to establish a multicenter, nationwide registry of atrial arrhythmia ablation procedures using the Pulsed Field Ablation (PFA) method.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Atrial Tachycardia, Ablation Techniques
- Trial name
- PFA Registry (NCT07109141)
- Testing
- PFA ablation procedure of atrial arrythmia
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Wroclaw Medical University
Atrial Fibrillation, Atrial Flutter
Left Atrial Thrombus on Transesophageal Echocardiography
The aim of the study is to assess the prevalence of left atrial thrombus in patients with atrial fibrillation (AF) or atrial flutter (AFI), in whom transesophageal echocardiography is performed before AF/AFl cardioversion or…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Transesophageal Echocardiography, Ablation
- Trial name
- LATTEE (NCT03591627)
- Testing
- Transesophageal echocardiography
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Atrial Flutter
Randomized Study of Radiofrequency- vs. Cryo-Ablation for Typical Isthmus-Dependent Atrial Flutter
This randomized study compares two energy sources for the catheter based ablation of typical isthmus-dependent atrial flutter: The (standard) radiofrequency (RF) ablation technique and the cryo-ablation technique regarding the…
- Trial name
- NCT00196170
- Testing
- RF ablation of the cavo-tricuspid isthmus, cryo ablation of the cavo-tricuspid isthmus, irrigated tip radiofrequency ablation of the cavo-tricuspid isthmus
- Where
- 4 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Atrial Fibrillation, Atrial Flutter
Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects
The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in female patients.
- Trial name
- NCT00126022
- Testing
- Tedisamil sesquifumarate
- Where
- 81 sites in United States, Argentina and 11 more
- Sponsor
- Solvay Pharmaceuticals
Atrial Fibrillation, Atrial Flutter
Risk Factors in Tachycardiomyopathy
Decision between rate control and rhythm control can be a challenge in clinical practice. While there is some guiding evidence, we still lack a comprehensive insight into different subgroups of patients that will benefit from a…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Ventricular Premature Complexes
- Trial name
- EMPATHY (NCT03418467)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Atrial Fibrillation and Flutter, Hyperthyroidism
Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone Stabilization
Patients with hyperthyroidism or hypothyroidism are often combined with atrial fibrillation, but after the stabilization of thyroid hormone levels after treatment, the patients' atrial fibrillation still persists.
- Conditions
- Atrial Fibrillation and Flutter, Hyperthyroidism, Hypothyroidism
- Trial name
- SQUIRREL (NCT06452823)
- Testing
- Catheter Ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Jiaxing University
Atrial Fibrillation
A Retrospective Study of the Role of Thiazolidinediones to Reduce the Incidence of Atrial Arrhythmias
It is well known that abnormal heart beats from the top parts of the heart, atrial fibrillation (AF) and atrial flutter (Aflut), occur frequently after most types of cardiac surgeries.
- Trial name
- NCT00321204
- Testing
- TZD reducing the incidence of atrial arrhythmias
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Stroke, Venous Thrombosis
Clarification of Optimal Anticoagulation Through Genetics
Individuals taking warfarin often need frequent dose changes as the international normalized ratio (INR) gets too high or too low which could result in a higher risk of thromboembolism, bleeding and early discontinuation of a…
- Conditions
- Stroke, Venous Thrombosis, Atrial Fibrillation, Atrial Flutter
- Trial name
- COAG (NCT00839657)
- Testing
- Genotype-guided dosing algorithm for warfarin, Clinical-guided dosing algorithm for warfarin
- Where
- 18 sites in United States
- Volunteers
- 1,015 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiac Arrythmias, Syncope
Confirm Rx™ Versus Reveal LINQ™ - Which is More Reliable in Data Transmission? A Randomized Clinical Study
This study will compare the reliability and timeliness in data transmission of the Abbott Confirm Rx™ loop recorder with the Medtronic Reveal LINQ™ loop recorder.
- Conditions
- Cardiac Arrythmias, Syncope, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT03720639
- Testing
- Abbott, Inc Confirm Rx™ versus Medtronic, Inc Reveal LINQTM
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Sparrow Clinical Research Institute
Atrial Fibrillation, Atrial Flutter
Evaluate the Pharmacokinetics and Safety of MK-4448 in Participants With Nonvalvular Atrial Fibrillation or Atrial Flutter
The primary purpose of this study is to optimize drug exposure in the target population.
- Trial name
- NCT01229254
- Testing
- Amiodarone, Betrixaban 60 mg, Betrixaban 90 mg
- Volunteers
- 189 people
- Sponsor
- Portola Pharmaceuticals
Anticoagulation, Atrial Fibrillation
AntiCoagulation Tracking InterVention and Evaluation
Anticoagulants are a leading cause of acute injury from adverse drug events, leading to ~20,000 serious injuries reported to the Food and Drug Administration per year and more than 220,000 emergency department visits annually.
- Conditions
- Anticoagulation, Atrial Fibrillation, Atrial Flutter, Pulmonary Embolus/Emboli
- Trial name
- ACTIVE (NCT04059965)
- Testing
- Panel Management for Anticoagulation Therapy, Usual Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Arrhythmias, Cardiac, Atrial Fibrillation
AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection
The study is a prospective single-arm multicenter clinical trial. Adult patients will be consented and enrolled in an outpatient cardiology office or Arrhythmia Clinics.
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Bradycardia
- Trial name
- VALID-ECG (NCT06123130)
- Testing
- Vectorcardiography (VECG)
- Where
- 5 sites in United States
- Volunteers
- 198 people
- Sponsor
- HeartBeam, Inc.
Paroxysmal Atrial Fibrillation
Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation
It has been demonstrated that successful cavotricuspid isthmus ablation may be effective in preventing paroxysmal atrial fibrillation. However, the effectiveness of only isthmus ablation on atrial fibrillation itself is unclear.
- Trial name
- NCT02031705
- Testing
- cavotricuspid isthmus ablation, control group
- Where
- South Korea
- Volunteers
- 366 people
- Sponsor
- Yong Seog Oh
Atrial Flutter
Radiofrequency Ablation Plus Botulinum Toxin Injection Versus Radiofrequency Ablation Only in Patients With Atrial Flutter
The aim of this randomized study was to assess the effectiveness of endomyocardial botulinum toxin injection for preventing post-procedural atrial fibrillation in patients undergoing the radiofrequency ablation of atrial flutter.
- Trial name
- NCT02002962
- Testing
- radiofrequency ablation, Botulinum Toxin Type A injection
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation