Clinical trials: AVM - Cerebral Arteriovenous Malformation
Intracranial Arteriovenous Malformations
Multimodal Imaging Techniques in Assessing the Surgical Risk for Eloquent Arteriovenous Malformations
Microsurgical resection for eloquent arteriovenous malformations (AVMs) remains challenging. Currently, there are only two grading systems concerning pretreatment assessment of brain AVMs: the Spetzler-Martin grading system…
- Trial name
- MITASREAVM (NCT02868008)
- Testing
- Microsurgical resection of brain AVMs
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Venous Insufficiency, Peripheral Arterial Disease
Outpatient Office Based Endovascular Procedures
The results of this study will serve as a starting point for future trials concentrating on the effectiveness and clinical outcomes of the procedures performed in an office based angiosuite.
- Conditions
- Chronic Venous Insufficiency, Peripheral Arterial Disease, Dialysis Access Malfunction, Arterio-venous Fistula
- Trial name
- NCT04054440
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Methodist Health System
Cerebrovascular Disease, Arteriovenous Malformations
Research on Hybrid Operation Technique in the Treatment of Complex Brain Arteriovenous Malformations
Complex brain arteriovenous malformations (bAVMs) in ≥3 Spetzler-Martin grades have long been challenges among cerebrovascular diseases.
- Conditions
- Cerebrovascular Disease, Arteriovenous Malformations, Complex; Primary
- Trial name
- HOTAVM (NCT03774017)
- Testing
- one-staged hybrid operation, Traditional microsurgical operation
- Where
- 7 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Supratentorial Neoplasms, Aneurysms
Scalp Nerve Blocks for Post-Craniotomy Pain
The objective of this study is to demonstrate that scalp nerve blocks ("scalp freezing"), performed at the end of supratentorial brain surgery, will reduce post-operative pain, opioids side effects, and the time required for…
- Conditions
- Supratentorial Neoplasms, Aneurysms, Arteriovenous Malformation, Epilepsy
- Trial name
- NCT00972790
- Testing
- Bilateral Scalp Nerve Blocks
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- Unity Health Toronto
Cerebral Arteriovenous Malformations
Liquid Biopsies for Detecting Somatic Mutations in Sporadic Cerebral Arteriovenous Malformations.
Cerebral arteriovenous malformations (CAVMs) are abnormal vessels located on the surface of the brain or within the cerebral parenchyma, causing abnormal communication between the arterial and venous networks, without the…
- Trial name
- BioMAV2 (NCT07103304)
- Testing
- Search for activating somatic genetic mutations
- Where
- 3 sites in France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Rouen
Cerebral AV Malformation
PHIL Evaluation in the Endovascular Treatment of Intracranial Cerebral ArterioVenous Malformation (cAVM)
The primary objective of this study is to assess the efficacy and safety of PHIL® liquid embolic agent in endovascular embolization of cerebral arteriovenous malformations.
- Trial name
- NCT03341039
- Where
- 16 sites in Denmark, France and 3 more
- Volunteers
- 20 people
- Sponsor
- Microvention-Terumo, Inc.
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Intracranial Aneurysm, AVM - Cerebral Arteriovenous Malformation
Postmarket Study of Tarvos Microguidewire in Neurovascular Interventional Surgery
This investigation is to evaluate the clinical effectiveness and safety of the Tarvos Microguidewire in the neurovascular interventional surgery.
- Conditions
- Intracranial Aneurysm, AVM - Cerebral Arteriovenous Malformation, AV Fistula, Acute Ischemic Stroke
- Trial name
- NCT07500155
- Testing
- Tarvos Microguidewire
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Keuro MedTech
Arteriovenous Malformations
Evaluation of Susceptibility-weighted Magnetic Resonance Imaging and 4d-time-resolved Magnetic Resonance Angiography in Brain Arteriovenous Malformations
Brain arteriovenous malformations are abnormal communications between brain arteries and veins with an intervening tangle of abnormal arteries (nidus).
- Trial name
- NCT03031873
- Testing
- MRI perfusion imaging
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ottawa Hospital Research Institute
Cerebral Hemorrhage, Intracranial Arteriovenous Malformations
MRI for the Early Evaluation of Acute Intracerebral Hemorrhage
What happens in the borderzone of a cerebral hemorrhage remains widely onknown and furhter the best timing for doing MR to look for vascular pathology in cerebral hemorrhage has not yet been determined.
- Conditions
- Cerebral Hemorrhage, Intracranial Arteriovenous Malformations, Intracranial Hemorrhage, Hypertensive, Brain Neoplasms
- Trial name
- NCT01689402
- Testing
- MRI Scan with the specified sequences below:
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Telangiectasia, Hereditary Hemorrhagic
Studies of Hereditary Hemorrhagic Telangiectasia
OBJECTIVES: I. Examine screening modalities for pulmonary vascular arteriovenous malformation (PAVM) in individuals with endoglin mutations. II.
- Trial name
- NCT00004648
- Volunteers
- 65 people
- Sponsor
- National Center for Research Resources (NCRR)
Intracranial Arteriovenous Malformations
Efficacy and Safety of the Liquid Embolic System (Tonbridge) for Endovascular Treatment of Cerebrovascular Malformations
The purpose of this study is to verify the efficacy and safety of the Liquid Embolic System (Tonbridge Medical Tech. Co., Ltd. (Suzhou)) for the treatment of cerebrovascular malformations.
- Trial name
- NCT06479343
- Testing
- Liquid Embolic System (Tonbridge), Onyx Liquid Embolic System (Medtronic)
- Where
- 14 sites in China
- Volunteers
- 170 people
- Sponsor
- Ton-Bridge Medical Tech. Co., Ltd
Cerebral Arteriovenous Malformations
Evaluation of ONYX in ENDOVASCULAR Treatment of Cerebral AVMs
To assess safety and efficacy of ONYX treatment for cAVM:
- Trial name
- cAVM (NCT02180958)
- Where
- 17 sites in France
- Volunteers
- 140 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation
Treatment of Brain AVMs (TOBAS) Study
The objectives of this study and registry are to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of…
- Conditions
- Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation, Arteriovenous Malformations, AVM
- Trial name
- TOBAS (NCT02098252)
- Testing
- Neurosurgery, Radiation therapy, Embolization
- Where
- 30 sites in United States, Brazil and 4 more
- Volunteers
- 1,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)