Clinical trials: Abdomen, Acute
Intra-abdominal Hypertension, Acute Respiratory Distress Syndrome (ARDS)
End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance Tomography-guided PEEP Titration Methods in Patients With Intra-abdominal Hypertension Combined With Acute Respiratory Distress Syndrome: a Randomized Crossover Controlled Study
This study aims to adopt a randomized crossover design to compare the effects of end-expiratory transpulmonary pressure-guided PEEP titration and EIT-guided PEEP titration on local lung ventilation, shunt, dead space, and…
- Trial name
- NCT06697717
- Testing
- Transpulmonary Pressure-Guided PEEP Titration in IAH and ARDS Patients, EIT-Guided PEEP Titration in IAH and ARDS Patients
- Where
- China
- Volunteers
- 15 people
- Sponsor
- XiaoJing Zou,MD
Appendicitis
Appendectomy vs. Symptomatic Treatment in Uncomplicated Acute Appendicitis Among Pediatric Patients
The APPSYPP trial is a randomized national multicenter feasibility superiority pilot study comparing appendectomy with symptomatic treatment in children with imaging-confirmed uncomplicated acute appendicitis.
- Trial name
- APPSYPP (NCT05289713)
- Testing
- appendectomy
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Helsinki University Central Hospital
Abdominal Aortic Aneurysm, Acute Myocardial Infarction
Body Mass Index and Initial Presentations of Cardiovascular Diseases
The association between obesity and cardiovascular disease (CVD) has mostly been studied using broad endpoints or have focused on cause-specific mortality.
- Conditions
- Abdominal Aortic Aneurysm, Acute Myocardial Infarction, Stroke, Heart Failure
- Trial name
- CALIBER (NCT01704300)
- Where
- United Kingdom
- Volunteers
- 2,240,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Acute Postoperative Pain
Combined Epidural Morphine and Midazolam on Postoperative Pain
this study aim to Compare the effect of preoperative Epidural Midazolam, Morphine and their combination in postoperative pain relief and total morphine consumption.
- Trial name
- NCT04033471
- Testing
- midazolam
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Appendicitis
EFFECT OF USING SAME DERMATOME LİNE FOR ALL PORT SİTES IN LAPAROSCOPIC APPENDECTOMY IN ACUTE APANDICITIS
Acute apandicitis is the one of most common cause of abdominal pain.Most of center still use open appendectomy(OA) technic for acute apandisitis.But Semm was defined Laparoskopic appendectomy(LA) with 3 ports in 1983.Today…
- Trial name
- DERMATOME (NCT03792802)
- Testing
- laparoscopic appendectomy port sites
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Acute Abdomen
Upper Gastrointestinal Perforations: a Nationwide Registry-based Study
The primary aim of this project is to increase the knowledge about how perforations in the esophagus, stomach and small intestine are treated on a national level.
- Trial name
- NCT06154603
- Testing
- Surgical treatment type
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
AKI - Acute Kidney Injury, CABG
Perfusion Related Evaluation of Systemic and Renal Vulnerability to Events in CABG
The goal of this observational study is to learn whether high abdominal pressure or low blood flow pressure to the kidneys is linked to kidney injury after heart surgery.
- Trial name
- PRESERVE-CABG (NCT07085286)
- Testing
- Continous IAP measurement
- Volunteers
- 45 people
- Sponsor
- Medical University of Lublin
Acute Appendicitis
Laparoscopic Versus Open Appendectomy
Appendectomy is the most common surgical procedure performed in emergency surgery. Because of lack of consensus about the most appropriate technique, appendectomy is still being performed by both open (OA) and laparoscopic (LA)…
- Trial name
- NCT02867072
- Testing
- Open appendectomy, Laparoscopic appendectomy
- Volunteers
- 593 people
- Sponsor
- University of Catania
Healthy, SIRS
A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA
This is a prospective, validation study of a extempore made tracer compared with a commercial. Studies with tracer have no medical effects but are used for studying human physiology, in this case pharmacokinetic variables of…
- Trial name
- NCT01686776
- Testing
- 123 I-HSA + 125 I HSA
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ake Norberg
Acute Mesenteric Ischemia, Sepsis Bacterial
Performance of the SeptiCyte LAB Test for Antibiotic Stewardship in Mesenteric Ischemia
This study will help determine whether the SeptiCyte LAB test can accurately differentiate between SIRS and actual infections in postoperative patients, potentially reducing unnecessary antibiotic use and improving patient…
- Conditions
- Acute Mesenteric Ischemia, Sepsis Bacterial, Intra-abdominal Infection, Digestive Inflammation
- Trial name
- SPASM (NCT06507423)
- Testing
- Septicyte Lab Test pre operative, Septicyte Lab Test post operative
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Central Hospital, Nancy, France
Acute Respiratory Distress Syndrome
Continuous Negative Abdominal Pressure in ARDS (CNAP in ARDS)
The aim is to test a device for applying continuous negative abdominal pressure in patients with ARDS
- Trial name
- CNAP in ARDS (NCT03425318)
- Testing
- CNAP
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Acute Cholecystitis, Endothelial Dysfunction
Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery
This study examines if remote ischemic preconditioning in patients undergoing minor acute abdominal surgery (laparoscopic cholecystitis due to acute cholecystitis) is associated with a modulation of endothelial dysfunction.
- Trial name
- PUMAS (NCT04156711)
- Testing
- Remote Ischemic Preconditioning (RIPC)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Acute High-risk Abdominal Surgery (AHA)
Early Mobilization Following Emergency Abdominal Surgery
Acute High-risk abdominal surgery (AHA) is associated with high mortality rates, multiple postoperative complications and prolonged duration of hospital admission.
- Trial name
- NCT03662932
- Testing
- Early intensive mobilization
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Morten Tange Kristensen PT, PhD
Gut Microbiota, Intra-abdominal Infections
Gut Microbiota Analysis in IAI Patients With Sepsis-associated Liver Dysfunction
With the rapid development of intensive care medicine, the mortality of patients with sepsis has decreased over the past decade, but it is still the leading cause of death in intensive care unit (ICU).
- Conditions
- Gut Microbiota, Intra-abdominal Infections, Acute Gastrointestinal Injury, Sepsis-associated Liver Dysfunction
- Trial name
- 2022-11-09 (NCT05628493)
- Testing
- Gut microbiota Analysis
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese Medical Association
Acute Appendicitis
Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology
The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis
- Trial name
- NCT06834958
- Testing
- Appendectomy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer, Hepatic, Cancer, Esophagus
Expectation, Pain Outcomes, and Pain Medication Following Oncology Abdominal Surgery: A Cohort Study
This study includes participants undergoing major hepatic surgery, surgery in the esophagus or stomach, or major surgery on the pancreas performed at Copenhagen University Hospital, Rigshospitalet.
- Conditions
- Cancer, Hepatic, Cancer, Esophagus, Cancer, Pancreas
- Trial name
- NCT07176052
- Testing
- cancer surgery
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Pain, Abdominal Pain
Comparison of Ketorolac at Three Doses in Children With Acute Pain
Hospital Scene #1: A 6-year-old arrives in the Emergency Department at McMaster Children's Hospital (MCH) complaining of pain in his lower right side.
- Conditions
- Acute Pain, Abdominal Pain, Migraine, Appendicitis Acute
- Trial name
- KETODOSE (NCT05641363)
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Canada
- Volunteers
- 171 people
- Sponsor
- Hamilton Health Sciences Corporation
Respiratory Tract Infections, Urinary Tract Infections
HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study
This study will analyze gene expression data (HostDx Sepsis test) from blood samples collected from participants with suspected infections.
- Conditions
- Respiratory Tract Infections, Urinary Tract Infections, Skin and Soft Tissue Infections, Intraabdominal Infections
- Trial name
- NCT03744741
- Testing
- HostDx Sepsis
- Where
- 7 sites in United States, Greece
- Volunteers
- 585 people
- Sponsor
- Inflammatix
Acute Appendicitis, Surgical Site Infection
Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy?
This study aims to evaluate the utility of double-ring wound-edge protectors to prevent the development of superficial surgical site infections after open appendectomy.
- Trial name
- sSSI-2RWEPs (NCT04860570)
- Testing
- Double-ring wound-edge protector
- Where
- Spain
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- Hospital Medina del Campo
Kawasaki Disease, Appendicitis
Acute Abdomen in Kawasaki Disease
Clinical and histopathological description of three cases of Kawasaki disease with acute abdomen.
- Trial name
- NCT03902262
- Testing
- appendicectomy
- Volunteers
- 3 people
- Sponsor
- National Institute of Pediatrics, Mexico