Clinical trials: Abdomen Disease
Incisional Hernia, Peritonitis
Prophylactic Implantation of Biologic Mesh in Peritonitis
Patients undergoing emergency surgery for peritonitis are at increased risk of abdominal wall-related complications. In patients with peritonitis the risk of incisional hernia (IH) is extremely elevated.
- Trial name
- NCT04681326
- Testing
- biological prosthesis
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Metabolic Syndrome, Abdominal Obesity
Copenhagen Obesity Risk Assessment Study
The aim of the present study is to assess the effect of a high intake of industrially produced trans fatty acids for 16 weeks on abdominal obesity and risk markers of type 2 diabetes and heart disease in healthy, moderately…
- Conditions
- Metabolic Syndrome, Abdominal Obesity, Heart Disease, Type 2 Diabetes
- Trial name
- COBRA (NCT00655902)
- Testing
- Trans fat (soy bean oil), Control fat (sunflower oil)
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Appendicitis
Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children
Despite growing popularity, practical advantages of single-port laparoscopic appendectomy (SLA) over conventional three-port laparoscopic appendectomy (CLA) have yet to be established well in pediatric population.
- Trial name
- PASTA (NCT03106467)
- Testing
- Single-port laparoscopic appendectomy, Three-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Hallym University Medical Center
Chronic Pain, Pelvic Pain
Vibratory Stimulation for the Treatment of Chronic Pain
The purpose of this study is to perform a first in man study with VCR stimulation of the belly and back for patients with chronic pain conditions including pelvic pain, functional abdominal pain, or low back pain.
- Conditions
- Chronic Pain, Pelvic Pain, Functional Abdominal Pain Syndrome, Low Back Pain
- Trial name
- NCT04069572
- Testing
- Vibrotactile Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Post Operative Analgesia, Opioid Sparing Anaesthesia
To Compare Post-op Analgesic Effectiveness of Ropivicaine+Dexamethasone and Ropivacane+Dexmetomidine in TAP Block in Stoma Reversal Under GA in Terms of Duration of Analgesia.
Controlling pain is of major concern in intra-operative as well as post-operative period inpatients undergoing all surgeries especially abdominal surgeries.Adequate pain control in post-operative period directly effect patient's…
- Conditions
- Post Operative Analgesia, Opioid Sparing Anaesthesia, Hypotension, Controlled, Bradycardia
- Trial name
- NCT07368075
- Testing
- TAP Block with Ropivacaine+Dexamethasone, TAP Block with Ropivacaine+Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Abdominal Aortic Aneurysms, Thoracoabdominal Aneurysms
Physician-Modified Endografts for Complex Aortic Aneurysms and Thoracoabdominal Aneurysm Repair in High-Risk Patients
This single-arm FDA-monitored protocol intends to broaden endovascular device applicability using physician-modifications in patients who A) Have anatomical conditions not amenable to endovascular repair using currently marketed…
- Conditions
- Abdominal Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aortic Aneurysm
- Trial name
- PMEG (NCT07224230)
- Testing
- Physician Modified Endograft
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Steven Maximus
Peripheral Arterial Disease, Carotid Stenosis
EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs
The purpose of this study is to determine the prevalence and risk factors, at the time of the diagnosis of PAD, for asymptomatic carotid stenosis and abdominal aortic aneurysm.
- Conditions
- Peripheral Arterial Disease, Carotid Stenosis, Abdominal Aortic Aneurysm
- Trial name
- EVART (NCT01224600)
- Testing
- patients with newly diagnosed PAD (<1year)
- Where
- 115 sites in Belgium, France
- Volunteers
- 1,056 people
- Sponsor
- Institut de l'Atherothrombose
Cervical Spinal Cord Injury
Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation
Compromised respiratory function as a result of tetraplegia is a leading cause of rehospitalisation for the tetraplegic patient group.
- Trial name
- NCT01800409
- Testing
- AFES
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- NHS Greater Glasgow and Clyde
Acute Abdomen in Children
Role of Multidetector Computerized Tomography (MDCT) in Diagnosis of Non Traumatic Acute Abdomen in Pediatric Age Group.
To evaluate the role of MDCT in diagnosis of non traumatic causes of acute abdomen in pediatric patients with clinical and surgical correlation.
- Trial name
- NCT04480983
- Testing
- Multidetector Computerized Tomography (MDCT)
- Volunteers
- 50 people
- Sponsor
- Amal Fathy Abo Elgarad
Acute Appendicitis
Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis
This study aims to evaluate the efficacy of Transversus Abdominis Plane (TAP) block in preoperative pain management for patients diagnosed with acute appendicitis who are scheduled for emergency surgery in the emergency…
- Trial name
- NCT06808737
- Testing
- Transversus Abdominis Plane Blockage
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ankara City Hospital Bilkent
Appendicitis
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
Several prior studies have demonstrated that medical management of acute appendicitis in adults is a safe first-line therapy option.
- Trial name
- NCT02991937
- Testing
- Piperacillin/Tazobactam, Surgical Treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural
Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
The investigators hypothesize that US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy resulting in…
- Trial name
- NCT06397300
- Testing
- bilateral Ultrasound guided erector spinae plane (ESP) block, quadratus lumborum block, lumbar epidural
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Aortic Aneurysm, Aortic Dissection
Cardiovascular Health Improvement Project
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure
- Trial name
- CHIP (NCT02306200)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Abdominal Aortic Aneurysm, Cardiovascular Events
Tonometry and Duplex Ultrasound to Predict AAA Progression and CV Events in Aneurysm Patients (1-2-3 Trial)
Abdominal aortic aneurysm (AAA) is a common vascular disease and associated with risk of rupture, but also with a high cardiovascular (CV) event rate.
- Trial name
- NCT03989011
- Testing
- Carotid Artery Reactivity test (CAR test), Arterial stiffness
- Where
- 3 sites in Netherlands
- Volunteers
- 167 people
- Sponsor
- Rijnstate Hospital
Aneurysm Abdominal
Reintervention Rates and Complications in Endovascular Aneurysm Repair (EVAR) and the Use of Colour Doppler Ultrasound (CDUS) and Computed Tomography Angiography (CTA) in Identifying Endoleak Complications
To provide a robust view of EVAR surveillance at UHL, this study proposes to retrospectively assess the surveillance programme to get a better view of post-operative complications following endovascular aneurysm repair.
- Trial name
- NCT07581392
- Where
- Ireland
- Volunteers
- 405 people
- Sponsor
- University Hospital of Limerick
Diabetes Mellitus, Type 2, Insulin Resistance
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes
This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D™ System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type…
- Trial name
- NCT03953963
- Testing
- HydraSolve T2D™
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medality Medical
Surgery--Complications
Effect of Multimodal Postoperative Rehabilitation on Functional and Cognitive Decline
Older adults, especially those with frailty, have a higher risk for complications, functional and cognitive decline after urgent surgery.
- Trial name
- NCT05290532
- Testing
- Individualized exercise training
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Hospital of Navarra
Tetraplegia, Spinal Cord Injury
Abdominal Functional Electrical Stimulation in Tetraplegia
People with high spinal lesions are at risk of respiratory complications because they have partial or complete paralysis of breathing muscles.
- Trial name
- NCT00202631
- Testing
- Surface Functional Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- South Glasgow University Hospitals NHS Trust
Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia
Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and…
- Conditions
- Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia, Analgesia, Lidocaine Adverse Reaction
- Trial name
- LARA (NCT05368753)
- Testing
- Blood sample, Lidocain, ropivacaine
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Abdominal Obesity, Type 2 Diabetes
ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT
Weight control is an essential part of treatment for type 2 diabetes (T2D) patients. Weight loss is associated with decreased haemoglobin A1c (A1c) levels.
- Trial name
- NCT05032001
- Testing
- Biguanide, DPP4 inhibitors, SGLT2 inhibitors
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Metabolic Research Unit