Clinical trials: Abdomen Disease
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
Ovarian Cancer
Tumor Gene Expression in Women With Ovarian Cancer
The study objective is to compare changes in expression of glucocorticoid-induced genes that may be involved in cell survival signaling in the tumors of ovarian cancer patients before and after an intraoperative dose of 20mg…
- Trial name
- NCT00817479
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Etomidate Combined With Propofol, Hypertension
Safety of Etomidate-propofol Mixture vs. Propofol for Total Intravenous Anesthesia in Elderly Patients Undergoing Abdominal Surgery
The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol for total intravenous anesthesia in elderly patients undergoing abdominal surgery.
- Trial name
- NCT07019246
- Testing
- EP mixture, Propofol
- Where
- China
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Treatment Resistant Schizophrenia, Obesity & Overweight
Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side Effects
The primary objective of the study is to assess the efficacy and tolerability of a 90-day daily supplementation with a Nitraria retusa dried crushed leaves infusion on the iatrogenic metabolic side effects induced in patients…
- Conditions
- Treatment Resistant Schizophrenia, Obesity & Overweight, Abdominal Obesity
- Trial name
- NCT07817069
- Testing
- The Nitraria retusa arm
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Faculty of Medicine, Sousse
Anxiety Disorders
Efficacy Study of Abdominal Massage Therapy to Treat Generalized Anxiety Disorder of Deficiency of Both Heart and Spleen Type
Generalized Anxiety Disorder (GAD) is characterized by the presence of persistent worry or fear of no explicit object and fixed content, or things that might occur in real life，which not corresponds with the realities.
- Trial name
- NCT02186366
- Testing
- Abdominal Massage Therapy, Buspirone
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sun Qing
Stomach Ulcer
Comparison of Intravenous Pantoprazole and Famotidine for Stress Ulcer Prophylaxis
Although stress ulcer is a complication that can cause significant mortality and morbidity in critical patients with risk factors, there is still lack of consensus about its prophylaxis.
- Trial name
- NCT00839488
- Testing
- pantoprazole 40 mg iv, famotidine 20 mg iv
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- Far Eastern Memorial Hospital
Postoperative Delirium (POD)
The Impact of Methylprednisolone Sodium Succinate on Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgery: A Target Trial Emulation Study
Glucocorticoids can be used to inhibit postoperative systemic inflammatory response syndrome. They may reduce the risk of major complications and mortality.
- Trial name
- NCT07271394
- Testing
- Administration of methylprednisolone sodium succinate during general anesthesia induction, No administration of methylprednisolone sodium succinate during general anesthesia induction
- Where
- China
- Volunteers
- 25,800 people
- Sponsor
- Chinese PLA General Hospital
Enhanced Recovery After Surgery, Appendicitis
Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children
Complicated appendicitis in pediatrics is frequent, potentially serious and complex to manage. The implementation of a ERAS model would allow optimizing perioperative care, offering a shorter hospital stay, reducing complications…
- Conditions
- Enhanced Recovery After Surgery, Appendicitis, Children, Only
- Trial name
- ERAS (NCT05511194)
- Testing
- Enhanced Recovery After Surgery therapeutic protocol, Conventional management
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Intra Abdominal Infections, Candidiasis, Invasive
Peritoneal 1.3-ß-D-glucan for the Diagnosis of Intra-abdominal Candidiasis in Critically Ill Patients (pBDG2)
New rapid diagnostic strategies are warranted in intra-abdominal candidiasis (IAC). A previous retrospective study showed that one measure, the day of the surgery, of peritoneal 1.3-Beta-D-Glucan ≤ 310pg/ml could rule out an IAC.
- Conditions
- Intra Abdominal Infections, Candidiasis, Invasive, Peritoneal Candidiasis, Critically Ill
- Trial name
- pBDG2 (NCT03997929)
- Testing
- 1.3 BETA D GLUCAN
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Abdominal Aortic Aneurysm
DOTATATE PETMRI AAA Study
Abdominal Aortic Aneurysm (AAA) screening and an aging population have increased the prevalence of AAA diagnoses. Small AAAs (<5.5cm) are monitored with ultrasound. Large AAAs may rupture and this is usually fatal.
- Trial name
- NCT04811222
- Testing
- Ga-DOTATATE PETMRI scan
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University Health Network, Toronto
Insulin Resistance
Role of Preoperative Carbohydrates Drinks, Dichloroacetate and Exercise on Postoperative Muscle Insulin Resistance
The aim of the study is to investigate whether preoperative interventions such as carbohydrate drinks, Dichloroacetate and exercise would inhibit or reverse the changes in molecular mechanisms regulating muscle carbohydrate…
- Trial name
- CARBEX (NCT02469337)
- Testing
- Dichloroacetate, Carbohydrate drinks, Moderate intensity exercise
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Infection Due to Resistant Bacteria, Pneumonia, Ventilator-Associated
Colistin and Rifampicin for MDR-Acinetobacter
Acinetobacter baumannii causes severe infections (pneumonia, bacteremia, organ space) with high lethality in hospitalised critically ill patients.
- Conditions
- Infection Due to Resistant Bacteria, Pneumonia, Ventilator-Associated, Hospital Acquired Pneumonia, Infection of Bloodstream
- Trial name
- CoRAb (NCT01577862)
- Testing
- Colistin, Rifampicin
- Volunteers
- 210 people
- Sponsor
- University of Campania Luigi Vanvitelli
Acute Appendicitis, Abdominal Pain
Diagnostic Performance of Serum Calprotectin in Acute Appendicitis
This prospective observational study evaluated the diagnostic performance of serum calprotectin in patients presenting with acute abdominal pain and suspected acute appendicitis.
- Trial name
- SCP-AA (NCT07643142)
- Testing
- Serum Calprotectin Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Abdominal Aortic Aneurysm (AAA)
Image Fusion of Preprocedural CTA With Real Time Fluoroscopy to Enhance EVAR Repair
Abdominal Aortic Aneurysm (AAA) is a potentially life threatening condition. If the aneurysm ruptures, the mortality can be as high as 80%.
- Trial name
- NCT02295137
- Testing
- Using pre-procedural CTA to guide advanced EVAR procedure
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Antiplatelet Agents, Perioperative Care
Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation
The purpose of this study is to evaluate the impact of perioperative aspirin continuation on clinical outcomes in patients with a history of coronary stent implantation who are scheduled for abdominal surgery.
- Trial name
- OPERATION (NCT06723145)
- Testing
- Aspirin, Aspirin interruption
- Where
- Japan
- Volunteers
- 1,200 people
- Sponsor
- Kyoto University
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Stress Urinary Incontinence, Pelvic Floor Muscle Weakness
Effectiveness of Pelvic Floor Muscle and Abdominal Training in Women With Stress Urinary Incontinence
The aim of this study was to investigate the effectiveness of pelvic floor muscle and abdominal training in reproductive-age patients with stress urinary incontinence.
- Trial name
- NCT03401983
- Testing
- Pelvic Floor Muscle Training and Abdominal Training, Pelvic Floor Muscle Training
- Volunteers
- 64 people
- Sponsor
- Trakya University
Umbilical Hernia
Visible vs. Non-Visible Mesh in Underlay Positon After Repair of Umbilical Hernias
The purpose of this study is to determine the exact position of a mesh which is placed in underlay position in umbilical hernia in vitro.
- Trial name
- NANEP (NCT03200405)
- Testing
- DynaMeshVisible, DynaMeshCICAT
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Wuerzburg University Hospital
Appendicitis
A Randomised Controlled Trial on LESS Versus Conventional Laparoscopic Appendicectomy.
LESS laparoscopic appendectomy is associated with less pain than conventional 3-port laparoscopic appendectomy.
- Trial name
- NCT01203566
- Testing
- LESS appendectomy, Conventional 3-port laparoscopic appendectomy
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Functional Gastrointestinal Disorders, Obesity, Childhood
Physical Exercise and Nutrition in Functional Gastrointestinal Disorders in Obese Children
A prospective observational case-control study evaluating the effect of a weight loss intervention program on functional gastrointestinal disorders among overweight and obese children.
- Trial name
- NCT06017856
- Testing
- Life style intervention program
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
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