Clinical trials: Abdomen Disease
Chronic Pancreatitis
Viokase 16, Viokase16 Plus Nexium and Nexium Alone
Our primary hypothesis is that the addition of Nexium to Viokase 16 will decrease the chronic abdominal pain in patients with small duct chronic pancreatitis in a superior fashion compared to Viokase 16 plus placebo or to Nexium…
- Trial name
- AZ (NCT01142128)
- Testing
- Nexium (esomeprazole magnesium), Viokase 16 (pancrelipase) + Nexium
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Postoperative Analgesia, Pain Management
Comparison of Intrathecal Morphine and Rectus Sheath Block for Postoperative Pain Management After Lower Abdominal Surgery With Midline Incision
This study aims to evaluate the efficacy of intrathecal morphine and rectus sheath block compared with standard postoperative analgesia for pain management in patients undergoing lower abdominal surgery with a midline incision.
- Trial name
- NCT07489872
- Testing
- Intrathecal Morphine, Rectus Sheath Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Premature Labor
Performance of the Monica Novii Wireless Patch System in Pre-term Labor
To study the equivalence of the Monica Novii™ Patch System in patients admitted for threatened pre-term labor and for pre-term labor \& delivery from 32 +0 weeks gestation by determining the equivalence of the Novii™ Patch System…
- Trial name
- NCT03057275
- Testing
- Abdominal fetal/maternal monitoring
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- GE Healthcare
Abdominal Pain, Deglutition Disorders
Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform
Through a four-year grant awarded to the University of California at Los Angeles in 2009, Dr. Brennan Spiegel served as a principal investigator (PI) for a project to develop and initially validate a bank of items to assess…
- Conditions
- Abdominal Pain, Deglutition Disorders, Fecal Incontinence, Nausea
- Trial name
- NCT02436057
- Testing
- AEGIS (Automated Evaluation of Gastrointestinal Symptoms)
- Where
- 3 sites in United States
- Volunteers
- 255 people
- Sponsor
- Cedars-Sinai Medical Center
Hypertrophic Skin Condition of Anterior Abdomen
Negative Pressure Wound Therapy-PICO: Cosmesis in Repeat C-Sections
There are millions of births each year with 32% of women undergoing cesarean sections (C-sections), which results in skin scarring. Repeat C-sections increased by 178% from 1979-2010.
- Trial name
- NCT05266053
- Testing
- PICO 7 dressing, Standard wound dressing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Myoma;Uterus
Transverse vs Longitudinal Incision in Myomectomy
The Aim of the study is to compare between transverse and longitudinal uterine incision in abdominal myomectomy regarding intraoperative blood loss.
- Trial name
- NCT03009812
- Testing
- Longitudinal uterine incision, Transverse uterine incision
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Obesity
Description of the Endothelial Phenotypes From the Subcutaneous Abdominal and Gluteo-femoral Adipose Tissues in Women
The endothelium is a key barrier between blood and tissue compartments. It is a major target of factors involved in metabolic and cardiovascular pathologies.
- Trial name
- ADIPENDO (NCT02672826)
- Testing
- Adipose tissue surgery
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Prostate Cancer
Postoperative Pain Control for Prostatectomy
The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.
- Trial name
- TAP (NCT00913068)
- Testing
- Transverse Abdominal Plan (TAP), standard post op pain control
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Nova Scotia Health Authority
Appendicitis, Appendicitis; Perforation
Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis
To determine the effectiveness of the use of probiotics in patients with a diagnosis of complicated appendicitis on antibiotic associated diarrhea (AAD).
- Trial name
- NCT04529980
- Testing
- Lactobacillus rhamnosus GG (LGG) Probiotic
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Children's Health
Obesity, Epidural; Anesthesia, Headache
Evaluation of Sagittal Abdominal Diameter as a Predictor of the Skin to Epidural Space Distance in Obese Patients
The aim of this study is to evaluate the use of the sagittal abdominal diameter (SAD) as a potential predictor of the skin to epidural space distance (SESD) and to compare its accuracy versus that of the BMI as a previously…
- Trial name
- NCT04095117
- Testing
- Epidural block
- Where
- 2 sites in Egypt
- Volunteers
- 135 people
- Sponsor
- Ain Shams University
Aneurysm
Brain and Abdominal Aneurysm Study
Aneurysmal subarachnoid hemorrhage (aSAH) is the most deadly kind of stroke. Each year, 40,000 Americans have SAH. Case-fatality approaches 60% and more than half of those who die do so before reaching the hospital.
- Trial name
- BAAS (NCT01420991)
- Where
- 2 sites in United States
- Volunteers
- 271 people
- Sponsor
- Mayo Clinic
Hernia, Obesity
Evaluation of Surgisis Gold Graft for Incision Reinforcement After Open Bariatric Surgery
The primary objective is to compare the effectiveness of the Surgisis Gold Graft to suture closure alone in preventing an incisional hernia after open bariatric surgery.
- Trial name
- NCT00274625
- Testing
- Surgisis Gold Graft, Control
- Where
- 2 sites in United States
- Volunteers
- 402 people
- Sponsor
- Cook Group Incorporated
Abdominal Aortic Aneurysms, Iliac Aneurysms
Zenith(R) Low Profile AAA Endovascular Graft Clinical Study
The Zenith® Low Profile AAA Endovascular Graft Clinical Study is a clinical trial approved by US FDA to study the safety and effectiveness of the Zenith® Low Profile AAA Endovascular Graft to treat abdominal aortic, aorto-iliac…
- Conditions
- Abdominal Aortic Aneurysms, Iliac Aneurysms, Aorto-iliac Aneurysms
- Trial name
- NCT00833924
- Testing
- Zenith(R) Low Profile AAA Endovascular Graft
- Where
- 27 sites in United States, China and 3 more
- Volunteers
- 120 people
- Sponsor
- Cook Group Incorporated
Surgery, Major Pancreatic, Surgery, Major Hepatic
Evaluating Health Literacy, Expectations and Regrets in Patients Undergoing Major Abdominal Surgery for Malignant Disease
Patients undergoing major abdominal surgery often have to make complex decisions about their treatment, where risks, benefits and possible complications must be considered.
- Conditions
- Surgery, Major Pancreatic, Surgery, Major Hepatic, Large Bowel/Sarcoma Resections, Surgery, Major Esophageal or Stomach
- Trial name
- NCT07450950
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Fabry Disease
Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Naïve Fabry Disease
The study will be a randomized, double blind, placebo-controlled study of the safety and efficacy of PRX-102 in ERT naïve male patients randomized 1:1. Patient age will be 14 to 45 years.
- Trial name
- NCT02921620
- Testing
- PRX-102
- Sponsor
- Protalix
Uterine Prolapse
Abdominal Versus Vaginal Hysteropexy
This study will compare the vaginal versus the abdominal approach for the management of uterine prolapse
- Trial name
- NCT03494582
- Testing
- Sacral Hysteropexy, sacrospinous Hysteropexy
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams Maternity Hospital
Ventral Hernia
Intraperitoneal Polypropylene Light Weight Wide Pore Soft Mesh Repair for Complex Ventral Hernia.
Complex ventral hernia is a challenging problem well known to be associated with occurrence of serious complications. The major problems encountered in such cases Include: loss of domain with subsequent increase of…
- Trial name
- NCT03994588
- Testing
- Intraperitoneal Mesh hernia repair
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Cairo University
Pneumoperitoneum
Intra-abdominal Pressure and Dynamic Preload Variables
Dynamic preload variables like pulse-pressure and stroke volume variation may be used to predict fluid responsiveness in patients during controlled ventilation.
- Trial name
- NCT02690688
- Testing
- determination of dynamic preload variables
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Luebeck
Overweight, Prediabetic State
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk of obesity-related conditions, including type 2 diabetes, hypertension, and…
- Conditions
- Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal
- Trial name
- ATTAIN-NOW (NCT07794579)
- Testing
- Orforglipron
- Where
- 180 sites in United States, Argentina and 10 more
- Volunteers
- 2,001 people
- Sponsor
- Eli Lilly and Company
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