Clinical trials: Abdomen Disease
Abdominal Aortic Aneurysm
LUCY Study: TriVascular Evaluation of Females Who Are Underrepresented Candidates for Abdominal Aortic Aneurysm Repair
The LUCY Study is a prospective, consecutively enrolling, non-randomized multi center post-market registry to evaluate the low profile Ovation ® Abdominal Stent Graft Platform when used in the endovascular treatment of female…
- Trial name
- LUCY (NCT02479191)
- Testing
- Ovation Abdominal Stent Graft Platform
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- TriVascular, Inc.
Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer
This phase I trial studies the side effects and best dose of paclitaxel for the treatment of gastric or gastroesophageal cancer.
- Conditions
- Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
- Trial name
- NCT04220827
- Testing
- Paclitaxel
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Carcinomatosis
Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis French Part of the Main Bev-IP Study
Selected patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) benefit from cytoreductive surgery (CRS) combined with intraperitoneal chemoperfusion (IPC).
- Trial name
- NCT03161041
- Testing
- Cytoreductive surgery combined with HIPEC, bevacizumab and HIPEC (Oxaliplatin 360 mg/m2).
- Sponsor
- Hospices Civils de Lyon
Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency
Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce…
- Trial name
- VD-PD (NCT05860270)
- Testing
- Cholecalciferol
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Peking University First Hospital
Abdominal Aortic Aneurysm Without Rupture
Pre-emptive Abdominal Aortic Aneurysm Sac Embolization During EVAR
Pre-emptive abdominal aortic aneurysm sac embolization during endovascular abdominal aortic repair for infrarenal abdominal aortic aneurysm - Randomized study
- Trial name
- NCT05575570
- Testing
- EVAR
- Volunteers
- 124 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Appendicitis, Other and Unspecified Acute Appendicitis
The Optimization of a Low-dose Computed Tomography Protocol in Patients With Suspected Uncomplicated Acute Appendicitis
This study focuses on the use of contrast enhanced low-dose CT imaging as a modality to differentiate between uncomplicated and complicated acute appendicitis.
- Conditions
- Appendicitis, Other and Unspecified Acute Appendicitis, Acute Disease, Gastrointestinal Diseases
- Trial name
- OPTICAP (NCT02533869)
- Testing
- Low-dose CT, Laparoscopic appendectomy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Obesity
Efficacy and Safety of Actiponin on Antiobesity in Obese Korean Subjects.
Obesity is a major health issue worldwide; there is a constant raise in obesity related death each year. In vitro and animal studies elucidated Actiponin as a novel anti-obesity agent.
- Trial name
- NCT01667224
- Testing
- Actiponin
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Ultrasonography
Ultrasound-guided Two Different Type Blocks for Pain Relief in Totalabdominal Hysterectomy
Effective analgesia after total abdominal hysterectomy is important for faster recovery and preventing complications which depend to pain.
- Trial name
- NCT04297046
- Testing
- PCA (patient controlled analgesia)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Peritoneal Carcinomatosis, Pancreas Neoplasm
Combined Nabpaclitaxel Pressurized IntraPeritoneal Aerosol Chemotherapy With Systemic Nabpaclitaxel-Gemcitabine Chemotherapy for Pancreatic Cancer Peritoneal Metastases
Combined chemotherapy consisting of endovenous Nabpaclitaxel-Gemcitabine and Nabpaclitaxel-PIPAC may be a promising treatment for patients affected by pancreatic cancer PM who are in need of curative options.
- Trial name
- Nab-PIPAC (NCT05371223)
- Testing
- Combined Nabpaclitaxel Pressurized IntraPeritoneal Aerosol Chemotherapy With Systemic Nabpaclitaxel-Gemcitabine
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Mansonelliasis, Pruritus
Epidemiology and Control of Mansonella Perstans Infection in Uganda
Mansonella perstans (M. perstans) infection is widespread in Uganda. Knowledge about the epidemiology of this infection, and of the morbidity it induces is poor, and no effective treatment is available.
- Conditions
- Mansonelliasis, Pruritus, Lymphoedema, Abdominal Pains
- Trial name
- NCT00215280
- Testing
- ivermectin and albendazole
- Where
- Uganda
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- DBL -Institute for Health Research and Development
Analgesia, Block
Trunks Body Blocks for Postoperative Analgesia in Abdominal Surgery
This study aims to the comparison of Quadratus Lumborum Block 2 and Transversus Abdominis Plan Block for Postoperative Analgesia in Abdominal Surgery
- Trial name
- NCT04143542
- Testing
- trunk blocks
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Abdominal Aortic Aneurysm
Effect of Pre-operative Exercise in Abdominal Aortic Aneurysms (AAA) Patients.
An aneurysm is a permanent and localized dilatation of an artery usually more than 50% of its normal diameter. Abdominal Aortic Aneurysms (AAA) is an aneurysm of the main artery of abdomen and affects 5% of men aged 65-74 years.
- Trial name
- NCT01062594
- Testing
- Supervised exercise, Role of exercise, Supervised exercise program
- Where
- United Kingdom
- Volunteers
- 124 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Fallopian Tube Cancer, Peritoneal Neoplasms
Predictors of Relapse of Ovarian, Peritoneal, and Fallopian Tube Cancers
This study will develop a blood test that can be used to predict a relapse of ovarian, peritoneal, or fallopian tube cancer. The type of testing is called proteomics, or the study of proteins in living cells.
- Conditions
- Fallopian Tube Cancer, Peritoneal Neoplasms, Epithelial Ovarian Cancer
- Trial name
- NCT00086567
- Where
- 11 sites in United States
- Volunteers
- 119 people
- Sponsor
- National Cancer Institute (NCI)
Obesity, Abdominal Surgery
Intraoperative Goal-directed Fluid Management
The investigators propose to determine esophageal Doppler goal-directed fluid requirements in lean, overweight, obese, and morbidly obese patients with the goal of developing a body mass index (BMI)-specific fluid replacement…
- Conditions
- Obesity, Abdominal Surgery, Hysterectomy, Genital Prolapse
- Trial name
- NCT00554944
- Testing
- Esophageal probe
- Where
- United States
- Sponsor
- The Cleveland Clinic
Abdominal Injury, Thoracic Diseases
A Post Market Study to Confirm the Safety and Performance of the Signia™ Stapling System.
The objectives of this prospective, two-arm, multicenter post-market study is to confirm safety and performance through the incidence of subjects reporting serious adverse device effects (ADEs) up to and including 30 days…
- Trial name
- NCT03515811
- Testing
- Signia™ Stapling System
- Where
- 11 sites in United States, Canada and 3 more
- Volunteers
- 136 people
- Sponsor
- Medtronic - MITG
Aggression, Attention Deficit-Hyperactivity
Metabolic Effects of Antipsychotics in Children
The project aims to describe and compare the outcome of 12 weeks of prospective, randomized treatment with olanzapine, risperidone or aripiprazole on insulin action in skeletal muscle, liver and adipose tissue, abdominal fat…
- Conditions
- Aggression, Attention Deficit-Hyperactivity, Oppositional Defiant Disorder, Pervasive Development Disorders
- Trial name
- MEAC (NCT00205699)
- Testing
- risperidone, olanzapine, aripiprazole
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Washington University School of Medicine
Gastroschisis
Multi-Centre Gastroschisis Interventional Study Across Sub-Saharan Africa
This study is a multi-centre interventional study at seven tertiary paediatric surgery centres in Ghana, Zambia, Malawi and Tanzania aimed at reducing mortality from gastroschisis.
- Trial name
- NCT03724214
- Testing
- Pre-hospital interventional care bundle, In-hospital interventional care bundle
- Where
- 9 sites in Canada, Ghana and 4 more
- Volunteers
- 235 people
- Sponsor
- King's College London
D000096704, Cannabinoid Hyperemesis Syndrome
Cannabinoid Hyperemesis Syndrome. Prospective Multicenter Study of Patients Admitted to Adult Emergency Departments in Maine-et-Loire.
Cannabinoid hyperemesis syndrome (CHS) is characterized by incoercible abdominal pain and vomiting in patients with chronic cannabis use. Patients are relieved by hot showers, an easily performed diagnostic test.
- Trial name
- CANN-AIE (NCT06660901)
- Where
- 3 sites in France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Angers
Ulcerative Colitis, Crohn Disease
Microbial and Human Determinants of the Onset of IBD Flares
This is a longitudinal, observational study that aims to identify the microbial and human molecular triggers of IBD flares via stool, saliva, and blood metatranscriptomes, whole blood proteome, and collected clinical metadata.
- Conditions
- Ulcerative Colitis, Crohn Disease, Irritable Bowel, Crohns Disease Aggravated
- Trial name
- NCT05463900
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Viome
Ruptured Appendicitis
Early Versus Interval Appendectomy for Ruptured Appendicitis in Children
The purpose of this randomized trial is to compare two commonly utilized surgical treatments for children with ruptured appendicitis: early appendectomy, versus interval appendectomy.
- Trial name
- RAPTOR (NCT00435032)
- Testing
- early appendectomy, interval appendectomy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Tennessee
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