Clinical trials: Abdominal
Abdominal Hysterectomy (& Wertheim), Intraoperative Complications
The Effects of Transversus Abdominis Plane Block in Patients Undergoing Total Abdominal Hysterectomy
The purpose of this study is to determine the effects of Transversus Abdominis Plane Block on hemodynamic variables, anaesthetic and analgesic requirement, and quality of recovery in patients undergoing total abdominal…
- Trial name
- TAP (NCT02296619)
- Testing
- TAP block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Tokat Gaziosmanpasa University
Metabolic Syndrome X
Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
The Metabolic Syndrome is a high prevalence disease worldwide. About a quarter of the adult population suffers the disease. Resveratrol is a substance found in many plants, including grapes, nuts and wine, but it's also found in…
- Trial name
- NCT02114892
- Testing
- Resveratrol
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- University of Guadalajara
Locally Resectable Pediatrics Tumors
CEB-01 in Pediatrics With Locally Resectable Abdominal Tumors
The CEB-01 implant is a membrane containing SN-38, the active metabolite of irinotecan, an already authorized chemotherapeutic agent.
- Trial name
- NCT06986811
- Testing
- Standard surgery, CEB-01
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- CEBIOTEX
Liver Diseases, Magnetic Resonance Imaging
High Resolution HBA-MRI Using Deep Learning Reconstruction
This study aims to compare image qualities between conventionally reconstructed MRI sequences and deep-learning reconstructed MRI sequences from the same data in patients who undergo Gd-EOB-DTPA enhanced liver MRI.
- Conditions
- Liver Diseases, Magnetic Resonance Imaging, Deep Learning
- Trial name
- NCT05182099
- Testing
- Liver MRI
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Recurrent Inguinal Hernia
Recurrent Inguinal Hernia Treatment - Lichtenstein Versus Laparoscopic Totally Extraperitoneal Preperitoneal Hernioplasty
The study aims at detecting possible differences between an open (Lichtenstein) and a video-assisted (TEP) technique in treating recurrent inguinal hernia.
- Trial name
- NCT00642200
- Testing
- Lichtenstein hernioplasty, Laparoscopic TEP
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- North Karelia Central Hospital
Peritoneal Carcinomatosis
Longitudinal Study of CRS/HIPEC for Peritoneal Carcinomatoses
Longitudinal Study of the Effect of Cytoreductive Surgery and HIPEC in Patients With Peritoneal Carcinomatoses
- Trial name
- CRS/HIPEC (NCT04108936)
- Where
- 2 sites in Germany
- Volunteers
- 250 people
- Sponsor
- University of Regensburg
Laparoscopic Surgery, Positive End-Expiratory Pressure
Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients
Abdominal laparoscopy is widely utilized due to its benefits, including minimal invasiveness, improved cosmetic outcomes, and shorter hospital stays.
- Conditions
- Laparoscopic Surgery, Positive End-Expiratory Pressure, Electrical Impedance Tomography
- Trial name
- PEEP-EIT (NCT06850844)
- Testing
- electrical impedance tomography, Conventional Ventilation
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Ventral Hernia
Sublay Versus Intraperitoneal Onlay Mesh Repair in Large Ventral Hernias
The aims of this study is to compare the efficacy of modified sublay hernioplasty versus intraperitoneal onlay mesh repair for large ventral hernias.
- Trial name
- NCT06643234
- Testing
- Ventral hernia repair
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahmed Kahlawy Mahrous Mohamed
Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy
Single Versus Double Dose Intra-vaginal Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy
Introduction: The study aimed to investigate the effectiveness of a single versus double dose of Prostaglandin E2 "Misoprostol, 400 microgram" during myomectomy for multiple uterine fibroids.
- Trial name
- NCT02154932
- Testing
- 2 doses 400 microgram misoprostol, single dose misoprostol
- Volunteers
- 69 people
- Sponsor
- Mansoura University
Inguinal Hernia, Postoperative Pain
Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia
The Erectore Spinae Plane Block (ESP Block) is a recently described technique for regional anesthesia that has shown promising results in the treatment of pain after thoracic surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Anesthesia, Local, Anesthesia Complication
- Trial name
- TAPESP (NCT04750512)
- Testing
- ESP block, TAP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ghielmini Enea
Traumatic Blunt Chest and/or Blunt Abdominal Injury
Hemodynamic and Ventilatory Responses to Head-down Postural Drainage Position
The purpose of this study is to explore acute hemodynamic and ventilatory responses to head-down 30 degree postural drainage position in patients with blunt chest and/or abdominal injury in the traumatic intensive care unit.
- Trial name
- NCT01668875
- Testing
- Head down 30 degree postural drainage position, Horizontal supine lying
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Hernia Repair, Hernia Inguinal
Postsurgical Analgesia After Hernia Repair
The study is designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of three ascending doses of AMT-143 to determine the appropriate dose of AMT-143 for the management of postsurgical pain following inguinal hernia…
- Conditions
- Hernia Repair, Hernia Inguinal, Hernia Surgery, Hernia, Inguinal/Surgery
- Trial name
- NCT06709612
- Testing
- AMT-143, ropivacaine
- Sponsor
- AmacaThera Inc.
Cesarean Section Complications
Sliding Sign in Late Trimester Ultrasound Evaluation of Intra-abdominal Adhesions in Women Undergoing Repeat CS
Predicting the presence of severe adhesions may also assist clinically in several ways: first, it allows allocation of more complicated surgeries to experienced surgeons; second, the surgeons can plan and prepare better for the…
- Trial name
- NCT06023381
- Testing
- Sliding sign
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Gastrointestinal Motility Disorder, Gastroparesis
IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy
Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions/ Some of these patients have serologic and/or endo organ…
- Conditions
- Gastrointestinal Motility Disorder, Gastroparesis, Neuropathy
- Trial name
- GAIN (NCT04208828)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Louisville
Obesity, Metabolic Syndrome
Effects of Exercise on Abdominal Obesity and Risk Factors for Cardiovascular Disease
The investigators will randomize abdominally obese men and women at increased health risk to one of the following 4 conditions: 1) No-exercise, wait list controls (C), 2) Low volume, low intensity exercise (LVLI), 3) High volume…
- Conditions
- Obesity, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT00955071
- Testing
- Exercise: LVLI, Exercise: HVLI, Exercise: LVHI
- Where
- Canada
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Queen's University
Pain, Postoperative
Comparison of Post-operative Pain in Short Versus Long Stitch for Laparotomy Closure
Laparotomy is a surgical procedure where an incision is made through the abdominal wall in order to gain access to the peritoneal cavity. Midline laparotomy incisions were the main type of abdominal access.
- Trial name
- Shortstitch (NCT03828409)
- Testing
- Short stitch, Long stitch
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pancreatic Neoplasms, Mediastinal Neoplasms
22G-Adapt Needle Biopsy Versus Fine-needle Aspiration in Endoscopic Ultrasound-guided Sampling of Solid Lesions
The investigators conduct a multicenter randomized controlled study to evaluate the diagnostic value and safety of 22G Adapt Aspiration puncture needle for histopathology of solid lesions.
- Conditions
- Pancreatic Neoplasms, Mediastinal Neoplasms, Abdominal Neoplasm, Excluding Pancreas Neoplasm
- Trial name
- NCT06563232
- Testing
- FNA group, Adapt FNB group
- Where
- China
- Volunteers
- 656 people
- Sponsor
- Huazhong University of Science and Technology
Ultrasound, Surgical
Ultrasound Guided Versus Surgical Rectus Sheath Block Versus Local Anesthesia Infiltration for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
The aim of this work is to compare the efficacy and safety of the effectiveness and safety of ultrasound-guided surgical rectus sheath block and local anesthetic infiltration for postoperative analgesia in patients undergoing…
- Conditions
- Ultrasound, Surgical, Rectus Sheath Block, Local Anesthesia Infiltration
- Trial name
- NCT06837532
- Testing
- Ultrasound-guided rectus sheath block, Surgical rectus sheath block, Local anesthesia infiltration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Wound; Abdomen
Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters
This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.
- Conditions
- Pain, Postoperative, Wound; Abdomen, Incision
- Trial name
- SPARC (NCT03137732)
- Testing
- Rectus Sheath Catheter
- Volunteers
- 50 people
- Sponsor
- Countess of Chester NHS Foundation Trust