Clinical trials: Abdominal Aorta Aneurysm
Abdominal Aortic Aneurysm
Cordis Bilateral AAA Device Compared to Open Surgical Repair of Abdominal Aortic Aneurysms (ARIBA)
The objective of this study is to assess the safety and effectiveness of the Cordis Bilateral AAA device and its Delivery System compared to open surgical repair for the treatment of Abdominal Aortic Aneurysm (AAA).
- Trial name
- NCT00235118
- Testing
- Cordis AAA Bilateral Device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Cordis US Corp.
Bowel Cancer Screening
Using Patient Navigation to Promote Bowel Screening in AAA Attendees.
The goal of this single-arm, multi-centre feasibility study is to assess the efficacy, feasibility and acceptability of implementing patient navigation across Abdominal Aortic Aneurysm (AAA) screening services in England to…
- Trial name
- TET BETA (NCT07721740)
- Testing
- Patient Navigation conversation
- Where
- United Kingdom
- Volunteers
- 4,190 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Abdominal Aorta Aneurysm
Circulating microRNAs and Degenerative Abdominal Aorta Aneurysm
Abdominal aortic aneurysm (AAA) is an aortic dilatation superior or equal to 30 mm with an estimated prevalence at 8% in men over 65 year-old.
- Trial name
- ACTA-miRNA (NCT03974958)
- Testing
- Tissue-library
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Abdominal Aortic Aneurysm
Neck Evolution With Ovation in Spain
This is a multicenter, observational, prospective, single arm registry using Ovation Alto Endograft. A minimum of 50 up to a maximum of 120 subjects undergoing endovascular repair with Ovation Alto endograft will be enrolled and…
- Trial name
- NEOVAS (NCT05823519)
- Testing
- Endologix Ovation Alto Endograft
- Where
- 9 sites in Spain
- Volunteers
- 120 people
- Sponsor
- DGM Vascular
Abdominal Aortic Aneurysm
Feasibility and Safety Study of the Endologix Fenestrated Stent Graft System
The aim of this study is to evaluate the safety and feasibility of the Endologix Fenestrated Stent Graft System for the endovascular repair of juxtarenal or pararenal aortic aneurysms.
- Trial name
- NCT01348828
- Testing
- Endovascular Aortic Aneurysm Repair (Endologix Fenestrated Stent Graft System)
- Where
- 8 sites in United States, Chile and 4 more
- Volunteers
- 49 people
- Sponsor
- Endologix
Abdominal Aortic Aneurysm (AAA)
ACZ885 for the Treatment of Abdominal Aortic Aneurysm
This study was designed to assess the safety, tolerability and efficacy of ACZ885 on aneurysmal growth rate in subjects with abdominal aortic aneurysms (AAA).
- Trial name
- AAA (NCT02007252)
- Testing
- ACZ885
- Where
- 9 sites in United States, Denmark and 3 more
- Volunteers
- 65 people
- Sponsor
- Novartis Pharmaceuticals
Aneurysm, Abdominal Aortic
First-in-Human Trial of the A3-Shield System for Stabilizing Abdominal Aortic Aneurysms
This clinical trial evaluates the safety and feasibility of the A3-Shield implant for stabilising small abdominal aortic aneurysms in adult patients.
- Trial name
- PRINCIPIIS-FIH (NCT07330752)
- Testing
- A3-Shield Implantation
- Where
- Uzbekistan
- Volunteers
- 12 people
- Sponsor
- Angiolutions GmbH
Aortic Diseases, Osteoarthritis, Hip
Pro-inflammatory Cytokines in Blood From Orthopedic Surgery Compared to Abdominal Aneurysm Repair
The purpose of this study is to investigate the contents in blood sampled from surgery site during hip replacement compared with blood sampled from abdominal aortic surgery.
- Trial name
- KEEP-HB (NCT00851149)
- Testing
- Sangvia blood sampling system
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Sykehuset i Vestfold HF
Abdominal Aortic Aneurysms
ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA
This is a Prospective Registry study to collect imaging and clinical data both on patients with aortic aneurysm disease undergoing serial monitoring and on patients pre and post-endovascular repair, using ViTAA (The Sponsor)…
- Trial name
- NCT05004051
- Testing
- ViTAA Analysis
- Where
- 8 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- ViTAA Medical Solutions
Abdominal Aortic Aneurysms
AAA Registry: Clinical Outcomes of Highly Angulated anatomY Treated With the Aorfix™ Stent Graft
The ARCHYTAS Registry is a long-term, global, multicenter, non-randomized, prospective, registry designed to collect "on-label" data in real world clinical settings on patients undergoing endovascular repair with the latest…
- Trial name
- ARCHYTAS (NCT02480595)
- Testing
- Stent Graft
- Where
- 37 sites in Czechia, Germany and 4 more
- Volunteers
- 500 people
- Sponsor
- Lombard Medical
Thoracic Aneurysm
Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery
The aorta is a large vessel that carries blood away from the heart. Sometimes it becomes dilated (swells) and this is known as 'aneurysm'. It may cause either dissection (splitting of the wall) or rupture (bursting).
- Trial name
- AZATAAR (NCT01889498)
- Testing
- Acetazolamide
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Aneurysm Abdominal, Endovacular Repair
Post Implantation Syndrome and Administration on NSAIDs in Patients Undergoing EVAR for AAA
INTRODUCTION Post-implantation syndrome is the clinical and biochemical expression of an inflammatory response following endovascular repair of an aortic aneurysm.
- Trial name
- NCT03727412
- Testing
- Drugs, Generic (Naprosyn)
- Where
- Greece
- Volunteers
- 186 people
- Sponsor
- University of Thessaly
Abdominal Aortic Aneurysm, Leriche Syndrome
CArbohydrate Loading in Aortic Surgery
The adverse effects of overnight fasting before surgery have been well-documented in the contemporary literature. Still, due to the possibility of pulmonary aspiration of gastric contents, many clinicians worldwide still employ…
- Trial name
- NCT06349382
- Testing
- carbohydrate-rich beverage
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Aorta Disease, Aorta Aneurysm
Assess Abdominal Aortic Diameter in Females
Female subjects aged 50 years or older will be enrolled. Biometric data (measurements) of the aorta and iliac vessels, demographic data, pathophysiological history, and data relating to menarche, pregnancy/infertility, and…
- Trial name
- AFRODITE (NCT07487961)
- Where
- Italy
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Abdominal Aortic Aneurism, Surgery
Study of the Glycocalyx in Abdominal Aortic Aneurysm
The investigators want to measure the degradation of the endothelial glycocalyx before and after clamping the aorta, in patients operated for a abdominal aortic aneurism.
- Conditions
- Abdominal Aortic Aneurism, Surgery, Ischemic Reperfusion Injury
- Trial name
- Endo_eAAA (NCT01834092)
- Testing
- Plasma
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Abdominal Aortic Aneurysm
Mechanism and Prevention of Remote Organ Injury Following Ruptured Aortic Aneurysm
It has been estimated that 80% of deaths from abdominal aortic aneurysms results from rupture. Endovascular Aneurysm Repair (EVAR) has been applied to RAAA (Ruptured Abdominal Aortic Aneurysm) patients with reports of…
- Trial name
- NCT00416000
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Abdominal Aorta Aneurysm
Performance and Safety of a Second Generation Antimicrobial Graft in Abdominal Position
Safety and performance of an anti-microbial vascular graft in the treatment of aneurysmal and occlusive disease of the abdominal aorta.
- Trial name
- SYNERGY (NCT01710878)
- Testing
- Intergard Synergy Graft
- Where
- 8 sites in France, Germany
- Volunteers
- 60 people
- Sponsor
- Maquet Cardiovascular
Abdominal Aortic Aneurysm, Image
AAA-CTA Cohort Registry
The aim of this study is to investigate the measurement of abdominal aortic aneurysm by computed tomography angiography. The research will collected the results of computed tomography angiography from inpatient, emergency, and…
- Trial name
- NCT07039825
- Testing
- Computed tomography angiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Abdominal Aortic Aneurysm
Safety and Efficacy of Allogeneic MSCs in Promoting T-regulatory Cells in Patients With Small Abdominal Aortic Aneurysms
This project is to determine the safety and explore the effectiveness of allogeneic (not cells of the participant but those of another human) mesenchymal stromal cells (MSCs) in decreasing inflammation and possible enlargement of…
- Trial name
- VIVAAA (NCT02846883)
- Testing
- 1 million MSCs/kg, 3 million MSCs/kg
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Abdominal Aortic Aneurysm
Metformin for Abdominal Aortic Aneurysm Growth Inhibition
A multi-centre population-based open-label randomized controlled trial with allocation concealment and blinded outcome assessment will examine if up to 2g metformin daily slows AAA growth in patients with small AAAs who do not…
- Trial name
- MAAAGI (NCT04224051)
- Testing
- Metformin, Standard care
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Uppsala University Hospital