Clinical trials: Abdominal Aorta Aneurysm
AAA - Abdominal Aortic Aneurysm, Aorta Aneurysm
Nectero EAST System Retreatment Study
This is an exploratory pilot study to evaluate the safety and clinical utility of retreatment with an investigational combination product called the Nectero EAST System to treat Abdominal Aortic Aneurysms or AAA.
- Conditions
- AAA - Abdominal Aortic Aneurysm, Aorta Aneurysm, Dilation Aorta
- Trial name
- NCT07505082
- Testing
- Nectero EAST System
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 10 people
- Sponsor
- Nectero Medical, Inc.
Anesthesia
Muscle and Cerebral Oxygenation Under EVAR of AAA: GA vs LA
The purpose of this study is to determine the effect of General versus Local Anaesthesia on muscle and cerebral oxygenation under EVAR-treatment in a prospective unblinded randomised controlled trail.
- Trial name
- NCT02555046
- Testing
- Local Anesthesia
- Volunteers
- 26 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Abdominal Aortic Aneurysm, Inflammatory Response
Post Implant Syndrome After EVAR and EVAS (INSPIRE Study)
Retrospective data have shown that active sac management, as applied in EVAS, reduces the incidence of the post-implant syndrome. All-cause and cardiac mortality at one-year seems to be lower after EVAS when compared to EVAR.
- Trial name
- NCT03763812
- Testing
- Endovascular Aneurysm Repair (EVAR), Endovascular Aneurysm Sealing (EVAS)
- Where
- 7 sites in Germany, Netherlands and 3 more
- Sponsor
- Rijnstate Hospital
Abdominal Aortic Aneurysm
Endoprosthesis Treatment Effects on Human Abdominal Aorta Aneurysms (AAA) Metabolic Activity
The purpose of this study is to determine whether Positron Emission Tomography imaging can help to predict the evolutivity of AAA treated with endovascular prosthesis.
- Trial name
- AAAendo (NCT01253252)
- Testing
- [18F] Fluorodeoxyglucose PET Scan Imaging, CT scan, Blood sampling for biological investigations
- Where
- 7 sites in France
- Volunteers
- 45 people
- Sponsor
- Central Hospital, Nancy, France
Abdominal Aortic Aneurysm
Sodium Fluoride Imaging of Abdominal Aortic Aneurysms
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to help predict the rate of abdominal aortic aneurysm expansion.
- Trial name
- SoFIA3 (NCT02229006)
- Testing
- 18F-NaF PET-CT
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Aortic Aneurysm Abdominal
Technical Evaluation and Results of the Use of TREO® Modular Aortic Endografts for the Treatment of Abdominal Aortic Aneurysms
This study is a clinical investigation as part of the post-market clinical follow-up of the TREO® abdominal aortic graft in its initial use, French, observational, multicenter, non-randomized, single-arm.
- Trial name
- RegisTREO (NCT06893952)
- Testing
- TREO Endograft
- Volunteers
- 209 people
- Sponsor
- Vascutek Ltd.
Thoracoabdominal Aortic Aneurysm, Pararenal Aortic Aneurysm
Guo's Visceral Arteries Reconstruction: First in Man Study
A First in man study to evaluate the safety and efficacy of thoracoabdominal aortic stent system for thoracoabdominal aortic aneurysms and pararenal abdominal aortic aneurysm.
- Trial name
- NCT04731636
- Testing
- Thoracoabdominal aortic stent system
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Aortic Aneurysm, Thoracoabdominal
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Aortic aneurysms represent the most common and dangerous aortic diseases. Although conventional aortic repair techniques cure the disease, there is a high risk of paraplegia particularly in extensive thoracoabdominal aneurysms…
- Trial name
- PAPAartis (NCT03434314)
- Testing
- Minimally-Invasive Segmental Artery Coil-Embolization
- Where
- 29 sites in Austria, France and 7 more
- Volunteers
- 500 people
- Sponsor
- University of Leipzig
Abdominal Aortic Aneurysm, Cardiovascular Events
Tonometry and Duplex Ultrasound to Predict AAA Progression and CV Events in Aneurysm Patients (1-2-3 Trial)
Abdominal aortic aneurysm (AAA) is a common vascular disease and associated with risk of rupture, but also with a high cardiovascular (CV) event rate.
- Trial name
- NCT03989011
- Testing
- Carotid Artery Reactivity test (CAR test), Arterial stiffness
- Where
- 3 sites in Netherlands
- Volunteers
- 167 people
- Sponsor
- Rijnstate Hospital
Abdominal Aortic Aneurysm
Contrast Enhanced Ultrasound Endoleak Identification and Classification
Surgery for abdominal aortic pathology usually occurs in the setting of advanced cardiovascular disease. The repair can be relatively simple or complex with multiple steps including open repair, placing a stent with a catheter…
- Trial name
- NCT04615559
- Testing
- Contrast enhanced ultrasound
- Where
- United States
- Sponsor
- University of Southern California
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture
BGP+ Stent as Bridging Stent in BEVAR
The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BGP+ balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany) implanted as…
- Trial name
- NCT03982940
- Testing
- BGP+ Stent Graft System as bridging stent
- Where
- 10 sites in Germany
- Volunteers
- 118 people
- Sponsor
- Marc Bosiers, MD
Abdominal Aortic Aneurysm
3D Ultrasound of Abdominal Aortic Aneurysm Characteristics
AAA characteristics are traditionally measured with computed tomography angiography (CTA), however, three-dimensional ultrasound (3D US) is emerging as a novel imaging method for AAAs.
- Trial name
- 3D US - EVAR (NCT05871515)
- Testing
- 3D ultrasound
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Abdominal Aortic Aneurysm, Iliac Aneurysm
Endovascular Exclusion of Abdominal Aortic Aneurysms in High Risk Patients
The purpose of this study is to assess the role of abdominal aneurysm and iliac aneurysm exclusion using an endovascular prosthesis.
- Conditions
- Abdominal Aortic Aneurysm, Iliac Aneurysm, Internal Iliac Aneurysm
- Trial name
- NCT00583414
- Testing
- Endovascular Aneurysm Repair
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- The Cleveland Clinic
Abdominal Aortic Aneurysm
REGISTRY on the Implementation of Artificial Intelligence in the Automatic Analysis of Vascular Network Segmentation
The team hypothesizes that fully automatic analysis of AAA could provide increased performance (decreased duration of segmentation with increased reproducibility and decreased inter and intraobserver variability) to detect aortic…
- Trial name
- IAVASC (NCT06451315)
- Testing
- Analyze CTscans pre-operatively by Nurea System, Analyze CTscans pre-operatively by hospital practitioner
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Bordeaux
Aneurysm Aortic
REGISTRY for the Use of a Software for Automatic Detection of the Evolution of Aneurysmal Volume and Graft Migration After EVAR (EndoVascular Aneurysm Repair)
The objective of this registry is to find and validate a correlation between morphological indicators such as volume sac evolution, graft migration or length between anatomical landmarks with aneurysm rupture risk or…
- Trial name
- AI-EVAR-FOLLOW (NCT05964348)
- Testing
- CT-Scan
- Where
- France
- Sponsor
- University Hospital, Bordeaux
Complex Abdominal Aortic Aneurysms
Patient-Reported Quality of Life After Open Surgery for Complex Abdominal Aortic Aneurysms: A Prospective Study
STUDY DURATION: January 2026 - December 2027 Each participant will be followed for 12 months postoperatively. BACKGROUND AND RATIONALE: Complex abdominal aortic aneurysms (cAAAs)-including juxtarenal, pararenal, and suprarenal…
- Trial name
- NCT07580443
- Testing
- To assess changes in health-related quality of life (HRQoL) using the Short Form-36 (SF-36) questionnaire
- Where
- 2 sites in Switzerland
- Volunteers
- 125 people
- Sponsor
- Prouse Giorgio
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Abdominal Aortic Aneurysms (AAA), Endovascular Aneurysm Repair (EVAR)
Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair
This study was a target trial emulation using the National Health Claims database established by the Korean National Health Insurance Service (K-NHIS). 8,325 patients were included.
- Trial name
- EVAR_DAPT_SAPT (NCT06876727)
- Volunteers
- 8,325 people
- Sponsor
- Samsung Medical Center
Abdominal Aortic Aneurysms, Abdominal Aortic Thrombosis
Mini-laparotomy Versus Mini Lumbotomy
This study aims to compare the results of two mini invasive surgical approaches in abdominal aortic surgery: mini lumbotomy with retroperitoneal approach versus mini laparotomy with transperitoneal approach.
- Trial name
- RAMini (NCT02888613)
- Testing
- mini laparotomy, mini lumbotomy
- Volunteers
- 206 people
- Sponsor
- Central Hospital, Nancy, France
Abdominal Aortic Aneurysm, Aorto-iliac Aneurysm
Zenith Low Profile AAA Endovascular Graft (ZLP) Clinical Study
A prospective study conducted in Japan to collect confirmatory peri-operative and 30-day information on use of the Zenith LP AAA Graft.
- Conditions
- Abdominal Aortic Aneurysm, Aorto-iliac Aneurysm, Iliac Aneurysm
- Trial name
- ZLP (NCT01326884)
- Testing
- ZLP
- Where
- 2 sites in Japan
- Volunteers
- 27 people
- Sponsor
- Cook Group Incorporated