Clinical trials: Abdominal Aorta Aneurysm
Carbon Dioxide, Endovascular Abdominal Aortic Aneurym Repair
Prospective, Non-Randomized Evaluation of Carbon Dioxide Gas as a Contrast Agent in Comparison With Iodinated Contrast in Endovascular Aneurysm Repair
Endovascular repair of infrarenal abdominal aortic aneurysms (AAA) requires a contrast agent to identify the vascular anatomy and placement of the stent graft.
- Conditions
- Carbon Dioxide, Endovascular Abdominal Aortic Aneurym Repair, Prospective, Angiogram
- Trial name
- NCT00520416
- Testing
- Carbon dioxide angiogram
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Abdominal Aortic Aneurysm, Arterial Stiffness
EndoVascular Aneurysm Repair: Heart Remodeling and Aortic Stiffness Study
Abdominal aortic aneurysm (AAA) is associated with a high burden of cardiovascular morbidity and mortality. Although endovascular aneurysm repair (EVAR) has become the preferred treatment for many patients with infrarenal AAA…
- Conditions
- Abdominal Aortic Aneurysm, Arterial Stiffness, Left Ventricle Remodeling
- Trial name
- EVAR-HRAS (NCT07722793)
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Abdominal Aortic Aneurysm > 5.5 cm Effect of a Restricted Intravenous Fluid Regime on Complications and Hospital Stay After the Minilaparotomy AAA Repair.
Restrictive Versus Standard Fluid Regime in Elective Minilaparotomy Abdominal Aortic Aneurysm Repair
Elective minilaparatomy abdominal aortic aneurysm (AAA) repair is associated with a significant number of complications involving respiratory, cardiovascular, gastrointestinal and central nervous system, and mortality ranging up…
- Trial name
- NCT01939652
- Testing
- Restrictive VS Standard Fluid Regime, Drag: Crystalloids and Colloids
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Clinical Center Tuzla
Aortic Aneurysm, Abdominal, Renal Insufficiency
Renal Function After Stentgraft Treatment Of Abdominal Aortic Aneurysm
This randomized controlled trial aim to determine the impact on renal function after treatment for infrarenal abdominal aortic aneurysm (AAA) with stentgrafts either with active supra- or infrarenal fixation.
- Conditions
- Aortic Aneurysm, Abdominal, Renal Insufficiency, Stent-Graft Thrombosis
- Trial name
- RENOFIX (NCT04754659)
- Testing
- Stentgraft
- Where
- Sweden
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Thoracoabdominal Aortic Aneurysm, Endovascular Repair of Aortic Aneurysm
ANATOMICAL FEASIBILITY OF BRAILE STANDARD BRANCHED ENDOGRAFT
The objective of this retrospective observational study is to evaluate the theoretical anatomical suitability of the new Braile off-the-shelf multi-branched endograft in patients with thoracoabdominal aneurysm.
- Conditions
- Thoracoabdominal Aortic Aneurysm, Endovascular Repair of Aortic Aneurysm, Vascular Diseases, Aortic Diseases
- Trial name
- BMETA (NCT07118995)
- Testing
- Analysis of preoperative CTA
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Braile Biomedica Ind. Com. e Repr. Ltda.
Peripheral Artery Disease, Abdominal Aortic Aneurysm
Endovascular Treatment of Aorto-iliac Disease Using in Situ Fenestration
In situ fenestration (ISF) could represent an alternative in the treatment of aorto-iliac disease when usual techniques are not available. The aim of this study was to present the results of ISF in aorto-iliac disease.
- Trial name
- PREFISIT (NCT04062734)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Aortic Aneurysm, AAA
First In Human Study for Small to Medium-sized Abdominal Aortic Aneurysm (AAA)
This is a first in human study to evaluate the safety and clinical utility of an investigational medical device called the Nectero EAST System to treat Abdominal Aortic Aneurysms or AAA.
- Conditions
- Abdominal Aortic Aneurysm, AAA, Dilation Aorta
- Trial name
- AAA (NCT05133492)
- Testing
- Endovascular Aneurysm Stabilization Treatment (EAST)
- Where
- 5 sites in Australia, China and 3 more
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nectero Medical, Inc.
Abdominal Aortic Aneurysm
Advanced MRI in AAA
This study aims to determine whether advanced MRI sequences can provide robust and clinically relevant information about abdominal aortic aneurysms (AAAs).
- Trial name
- NCT03138434
- Where
- Netherlands
- Volunteers
- 31 people
- Sponsor
- Ron Balm
Aneurysm Abdominal, Cerebral Aneurysm Ruptured
Occurrence of Abdominal Aortic Aneurysms in Patients With Aneurysmal Subarachnoid Hemorrhage
Rationale: Aneurysms of different types are known to be associated. In literature, concurrence of intracranial- and aortic aneurysms is described.
- Trial name
- TRACE-aSAH (NCT07312565)
- Where
- Netherlands
- Volunteers
- 233 people
- Sponsor
- Leiden University Medical Center
Abdominal Aortic Aneurysm
Ultrasound Velocimetry in the Abdominal Aorta Before and After Endovascular Aneurysm Repair
Rationale: An abdominal aortic aneurysm (AAA) is a common vascular disease with a high mortality in case of rupture. The underlying processes initiating aneurysmal degeneration and driving aneurysmal growth remain poorly…
- Trial name
- EchoPIV in AAA (NCT05148988)
- Testing
- EchoPIV, 4D flow MRI
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Rijnstate Hospital
Abdominal Aortic Aneurysms (AAA)
The Pivotal Study of the Aptus Endovascular AAA Repair System
A prospective, non-randomized, multi-center clinical study to evaluate the safety and effectiveness of the Aptus Endovascular AAA Repair System compared to an open surgical repair historical control group in the treatment of…
- Trial name
- STAPLE-2 (NCT00507559)
- Testing
- Aptus Endovascular AAA Repair System
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- Medtronic Cardiovascular
Coronary Artery Disease, Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Screening Before Coronary Artery Bypass Surgery
Coronary artery disease (CAD) and abdominal aortic aneurysm (AAA) are two separate entities with common risk factors such as hypertension, advanced age, male sex.
- Trial name
- NCT05449509
- Testing
- Abdominal aortic Duplex ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Abdominal Aortic Aneurysm, Endoleak
EndoVascular Aortic Repair With Sac Embolization for the Prevention of Type II Endoleaks (the EVAR-SE Study)
Beyond a certain threshold diameter, Abdominal aortic aneurysms (AAA) are treated by open surgical repair or, more often by endovascular aortic aneurysm repair (EVAR).
- Trial name
- EVAR-SE (NCT05665101)
- Testing
- Coil embolization of aneurysm sac
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Univ.-Prof. Dr. Dr. med. Daniela Branzan
Abdominal Aortic Aneurysm Without Rupture
The British Society of Endovascular Therapy ConformabLe EndoVascular Aneurysm Repair Registry
The purpose of the BSET-CLEVAR Registry is to collect device-specific performance outcomes of the GORE® EXCLUDER® Conformable AAA Endoprosthesis with ACTIVE CONTROL System (EXCC device) in routine clinical treatment of patients…
- Trial name
- BSET-CLEVAR (NCT03966521)
- Where
- 13 sites in United Kingdom
- Volunteers
- 105 people
- Sponsor
- Imperial College London
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Abdominal Aortic Aneurysm, Deep Vein Thrombosis
Evaluation of a New Imagingtechnologie for Thrombosis
Arterial and venous thrombi play an important role in various vascular diseases such as myocardial infarction, stroke, transient ischemic attacks (TIA) and pulmonary embolism.
- Trial name
- PET-GP1_1 (NCT02469376)
- Testing
- [18F]-GP1
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University of Zurich
Cardiovascular Diseases, Abdominal Aortic Aneurysm
Non-invasive Monitoring of Endovascular Repair of Abdominal Aortic Aneurysm (VBA)
This study evaluates a novel noninvasive method to dynamically monitor the effect of abdominal aortic aneurysm (AAA) and endovascular treatment of AAA (EVAR) on arterial pulse wave
- Trial name
- VBA (NCT03493074)
- Testing
- Noninvasive pulse wave analysis sensor, ECG-sensor
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Abdominal Aortic Aneurysm
ANEUFIX for Endoleaks Type II
The study is a non-randomized, multi-center safety and feasibility trial of Aneufix ACP-T5 to treat patients with Isolated type II endoleak in the presence of a non-shrinking AAA sac following an EVAR procedure.
- Trial name
- ACP-T5 (NCT02487290)
- Testing
- Aneufix ACP-T5
- Where
- 2 sites in Netherlands
- Volunteers
- 4 people
- Sponsor
- TripleMed B.V.
Abdominal Aortic Aneurysm, Pulse Wave Analysis
The Effect of Surgery on Central Aortic Pressure & haEmodynamics Study
The present study will investigate the effect of artificially stiffening the aorta by means of an aortic stent on central aortic haemodynamics (CAH).
- Conditions
- Abdominal Aortic Aneurysm, Pulse Wave Analysis, Risk
- Trial name
- ESCAPE (NCT02493296)
- Testing
- This observational study will not entail an intervention.
- Where
- United Kingdom
- Volunteers
- 146 people
- Sponsor
- University of Leicester
Abdominal Aorta Aneurism, Peripheral Arterial Disease
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression: the Prospective VASCUL-AID Study
Introduction: Peripheral arterial disease (PAD) and abdominal aortic aneurysm (AAA) are vascular conditions associated with significant morbidity and mortality, with 25% of AAA patients and 23% of PAD patients being at a high…
- Trial name
- VASCUL-AID-PRO (NCT07187700)
- Volunteers
- 1,100 people
- Sponsor
- Amsterdam UMC