Clinical trials: Abdominal Aortic
Thoracoabdominal Aortic Aneurysm
"Percutaneous Axillary Access in the Endovascular Treatment of Thoracoabdominal Aortic Pathology" (PAXA)
Since the development of custom-made fenestrated and branched endografts a novel therapeutic option for the management of thoracoabdominal and para-renal aortic aneurysms was made accessible.
- Trial name
- PAXA (NCT03223311)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Safety and Performance of the Nellix Endovascular Sealing System
Nellix® Registry Study: EVAS-Global
This registry has been designed as a multicenter, single arm, open label, post-market registry study with consecutive, eligible patient enrollment at each site.
- Trial name
- EVAS-FORWARD 1 (NCT02018744)
- Where
- 19 sites in Germany, Latvia and 6 more
- Volunteers
- 300 people
- Sponsor
- Endologix
Postoperative Pain
Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm Repair
The aim of the study is to determine wether continuous wound infusion with local anaesthetic plus a single dose intravenous morphine is non-inferior to postoperative analgesia provided with continuous thoracic epidural infusion…
- Trial name
- APERIVIP (NCT02677532)
- Testing
- Paracetamol, Levobupivacaine wound infiltration, Levobupivacaine epidural bolus
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- University of Genova
Aortic Aneurysm, Abdominal
Predicting Rupture of AAA by Anatomic and Hemodynamic Markers
The purpose of the study is to investigate imaging findings, which can help us to predict factors contributing to abdominal aortic aneurysm growth and rupture.
- Trial name
- NCT02463760
- Testing
- Medical imaging
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Coronary Artery Disease (CAD)
Abdominal Aortic Calcium and CAD-RADS 2.0
Background: Abdominal aortic calcium (AAC) is a marker of systemic atherosclerosis and may predict cardiovascular outcomes similarly to coronary artery calcium (CAC).
- Trial name
- NCT06956924
- Testing
- CCTA
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chang Gung Memorial Hospital
Abdominal Aortic Aneurysm
Powerlink Bifurcated Stent Graft Long-Term Follow-up Study
Endologix Infrarenal Bifurcated Stent Graft Study
- Trial name
- NCT00543270
- Testing
- Powerlink infrarenal bifurcated stent graft delivery system, Open Surgery
- Where
- 14 sites in United States
- Volunteers
- 258 people
- Sponsor
- Endologix
Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations
Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair
This study will evaluate the impact of complex thoraco-abdominal aortic aneurysm repair in coagulation during the immediate postoperative period in patients undergoing omplex thoraco-abdominal aortic aneurysm repair.
- Conditions
- Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations, Platelet Activation
- Trial name
- CoFA-TAAA (NCT06432387)
- Testing
- Patients undergoing complex thoraco-abdominal aortic aneurysm repair
- Where
- 2 sites in Greece
- Volunteers
- 58 people
- Sponsor
- University of Thessaly
Aortic Aneurysm, Aortic Aneurysm Abdominal
Evaluation of the iCover Stent as a Bridging Stent in Fenestrated Endovascular Aneurysm Repair (fEVAR) for Complex Aortic Aneurysms.
ReiCo is a French retrospective, multicenter, single-arm study focused on assessing the safety and clinical performance of the iCover balloon-expandable covered stent (iVascular) when implanted as a bridging stent during fEVAR…
- Trial name
- ReiCo (NCT07742254)
- Where
- 3 sites in France
- Volunteers
- 154 people
- Sponsor
- iVascular S.L.U.
Hemorrhage, Simulation Training
Mixed-reality REBOA Simulator With Virtual Coaching
Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is a life-saving emergency procedure that is highly suited for simulation-based training.
- Trial name
- REBOASIM (NCT05062928)
- Testing
- Virtual coach
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aortic Aneurysm, Aortic Aneurysm, Abdominal
Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair
Complex aortic aneurysms involving major branches have been difficult endovascularly. The primary purposes of this study is to evaluate the safety, feasibility, and efficacy of multiple overlapping uncovered stents in treating…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Aortic Aneurysm, Thoracoabdominal
- Trial name
- SEMPER (NCT01985906)
- Testing
- Multiple overlapping uncovered stents, Uncovered stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
AAA - Abdominal Aortic Aneurysm
Sex-specific Differences in AAA Complexity
A retrospective cohort study of computed tomography scans of AAA patients considered for repair, in order to identify sex specific differences in abdominal aortic aneurysm (AAA) metrics and the association between anatomical…
- Trial name
- NCT05399706
- Testing
- CTA Aorta
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Imperial College London
AAA, Abdominal Aortic Aneurysm
Central Blood Pressure and Variability Evaluation
Background: A sub-study of the AARDVARK (Aortic Aneurysmal Regression of Dilation: Value of ACE-Inhibition on RisK) trial indicated a statistically significant association between central blood pressure (BP) variability and…
- Conditions
- AAA, Abdominal Aortic Aneurysm, Blood Pressure
- Trial name
- CAVE-ON (NCT05376514)
- Where
- 2 sites in United Kingdom
- Volunteers
- 137 people
- Sponsor
- Imperial College Healthcare NHS Trust
AAA - Abdominal Aortic Aneurysm
Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System China Study(ATHENA)
To evaluate the safety and effectiveness of the Heli-FX EndoAnchor system in AAA subjects who without augmented radial fixation and/or sealing due to an endoleak or migration are at high risk for aneurysm-related complications or…
- Trial name
- ATHENA (NCT07754318)
- Testing
- Heli-FX EndoAnchor System
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Medtronic Cardiovascular
Postpartum Haemorrhage (PPH)
Temporary Aortic Occlusion With the Abdominal Tourniquet for Refractory Postpartum Haemorrhage: A Proof-of-Concept Study in a War-Affected Region
The purpose of this study is to evaluate whether a medical device called the Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S) can safely and effectively temporarily stop severe bleeding after childbirth (known as…
- Trial name
- TAOAT (NCT07016568)
- Testing
- Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S)
- Where
- Ukraine
- Volunteers
- 4 people
- Sponsor
- LLC UkrMedGroup
Thoracoabdominal Aortic Aneurysm, Without Rupture
Branched Thoracic Endovascular Grafts for the Treatment of Thoraco-abdominal Aortic
An investigator-initiated, prospective, consecutively enrolling, non-randomized single institution clinical evaluation of the safety and effectiveness of branched and fenestrated-branched endovascular stent grafts to preserve…
- Trial name
- B-TEVAR (NCT01874197)
- Testing
- B-TEVAR device
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- University of Washington
Renal Cell Carcinoma (Kidney Cancer), Kidney Cancers
Targeted Abdominal CT in Conjunction With Lung Cancer Screening
Early detection through screening can improve cancer survival by identifying it when it's most treatable. The NHS now offers Lung Cancer Screening (LCS) assessments to people aged 55-74 who have ever smoked.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Kidney Cancers, AAA - Abdominal Aortic Aneurysm, Renal Stones
- Trial name
- TACTICAL1 (NCT07171190)
- Testing
- Lung Cancer Screening Invitation Intervention, Abdominal scan intervention
- Where
- United Kingdom
- Volunteers
- 6,272 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Abdominal Aortic Aneurysm
3D Ultrasound of Abdominal Aortic Aneurysm Characteristics
AAA characteristics are traditionally measured with computed tomography angiography (CTA), however, three-dimensional ultrasound (3D US) is emerging as a novel imaging method for AAAs.
- Trial name
- 3D US - EVAR (NCT05871515)
- Testing
- 3D ultrasound
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Abdominal Aortic Aneurysm
Biomarker Profiling in Abdominal Aortic Aneurysm Patients
The BIOMArCS-AAA study aims to investigate the associations of (temporal patterns of) blood biomarkers with aneurysm growth in patients with abdominal aortic aneurysm (AAA), with particular attention to biomarkers that have…
- Trial name
- BIOMArCS-AAA (NCT03703947)
- Where
- 2 sites in Netherlands
- Volunteers
- 440 people
- Sponsor
- Erasmus Medical Center
Aortic Disorders, Carotid Disease
A Multicenter Study of Iomeron®-400 Used With Multi-detector Computed Tomography Angiography (MDCTA)
This is a Phase IV multicenter, open-label study and is being implemented in order to assess diagnostic image quality of MDCTA in subjects undergoing computed tomography angiography (CTA) of the thoraco-abdominal aorta, and the…
- Conditions
- Aortic Disorders, Carotid Disease, Pulmonary Disease, Peripheral Artery Disease
- Trial name
- Iomeron®-400 (NCT02596048)
- Testing
- Iomeron
- Where
- 5 sites in China
- Volunteers
- 224 people
- Sponsor
- Bracco Diagnostics, Inc
Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Excluder / Excluder Conformable AAA Endoprosthesis in subjects with Abdominal…
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder), Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
- Trial name
- ADVANCE (NCT05378347)
- Testing
- Medtronic Endurant II or Endurant IIs Stent Graft System, Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
- Where
- 68 sites in United States, Finland and 10 more
- Volunteers
- 600 people
- Sponsor
- Medtronic Cardiovascular