Clinical trials: Abdominal Aortic Aneurysms
Abdominal Aortic Aneurysm
Sodium Fluoride Imaging of Abdominal Aortic Aneurysms
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to help predict the rate of abdominal aortic aneurysm expansion.
- Trial name
- SoFIA3 (NCT02229006)
- Testing
- 18F-NaF PET-CT
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Abdominal Aortic Aneurysm
Reduction of Myocardial Infarction by Preconditioning in Patients With Ruptured Abdominal Aortic Aneurysm
Preconditioning in patients treated for elective abdominal aneurysm showed that the rate of perioperative myocardial infarction could be reduced by 80 %(ARR from 27% to 5%).
- Trial name
- PreconRAAA (NCT00883363)
- Testing
- Precondition
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Nikolaj Eldrup
AAA - Abdominal Aortic Aneurysm
Prediction of Abdominal Aortic Aneurysm Shrinkage After Stent-placement With Artificial Intelligence
The goal of this observational study is to find out what factors contribute to a good treatment outcome in patients who have received a stent for their dilation of the main abdominal artery (abdominal aortic aneurysm or AAA).
- Trial name
- ARTinEVAR (NCT06250998)
- Where
- 5 sites in Netherlands, Sweden
- Volunteers
- 1,000 people
- Sponsor
- Rijnstate Hospital
Abdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured
Prospective Aortic Biobank of POP-STAR
The overall objective of the POP-STAR project is individualized surveillance for patients diagnosed with abdominal aortic aneurysms by means of more precise, patient-specific AAA growth prediction.
- Conditions
- Abdominal Aortic Aneurysm Without Rupture, Abdominal Aortic Aneurysm, Ruptured, Aortic Aneurysm, Aneurysm Abdominal
- Trial name
- NCT04269447
- Testing
- Structured imaging follow-up
- Where
- 2 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Aortic Aneurysm, Abdominal
Cortisol Response to Adrenocorticotrophin (ACTH) in Acute Stress
Cortisol deficiency is diagnosed by the adrenocorticotrophin (ACTH) stimulation test. This test measures cortisol levels in the blood before and after giving an injection of ACTH.
- Trial name
- CRAAS (NCT00493389)
- Testing
- Adrenocorticotrophic hormone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Ottawa
Abdominal Aortic Aneurysm, Endovascular Abdominal Aortic Aneurysm Repair
Intraoperative Assessment of Pulsatile Aneurysm Wall Motion During Endovascular Aneurysm Repair
Endovascular abdominal aortic aneurysm repair (EVAR) aims to reduce the risk of aneurysm (AAA) rupture by reducing the blood pressure transmitted to the wall of the aneurysm.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Abdominal Aortic Aneurysm Repair, Ultrasound
- Trial name
- NCT03993496
- Testing
- Abdominal Aortic Aneurysm Sac Pulsatility
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Ottawa
Abdominal Aortic Aneurysm Without Rupture
ShorT Stay Aneurysm Repair Study
A prospective observational cohort study to assess the eligibility, uptake, viability, acceptability, safety, and cost of a ShorT stay (23-hour) Aneurysm Repair (STAR) pathway. Outcomes will be collected for up to 1 year.
- Trial name
- STAR (NCT05279274)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
PAD, Abdominal Aortic Aneurysm
Use of Fish Oil to Reduce Inflammation During Endovascular Abdominal Aortic Repair
The purpose of this study is to determine if high-dose PUFA supplementation in patients undergoing EVAR for infra-renal AAA reduces the peri-operative inflammation.
- Trial name
- Omega-EVAR (NCT03208920)
- Testing
- Pro-Omega
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Aortic Aneurysm
ANCHOR (Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System Global Registry)
The ANCHOR registry is a multi-center, post-market, non-interventional, non-randomized, prospective study. Subjects must sign an ICF prior to obtaining any study specific information.
- Trial name
- ANCHOR (NCT01534819)
- Testing
- EndoAnchor™, endovascular treament
- Where
- 87 sites in United States, Australia and 11 more
- Volunteers
- 1,090 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Aortic Aneurysm
ALTo endogrAft Italian Registry
The aim of present study is to evaluate intraoperative, peri-operative, and post-operative results in patients treated by the ALTO stent graft (Endologix Inc.
- Trial name
- ALTAIR (NCT05234892)
- Testing
- ALTO endograft implantation
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Gianmarco de Donato
Aortic Aneurysms
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of pararenal, supra-renal and type 4 THORACO-abdominal aortic…
- Trial name
- Windows1 (NCT01168037)
- Testing
- Endovascular aortic repair with branched/fenestrated stent-graft, Open Surgical Repair
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Aortic Aneurysm
GORE® EXCLUDER® Endoprosthesis French Mandatory Registry
This is a French Registry mandated by the French National Health Authority assessing long-term (5-years) safety of the GORE® Excluder® Endoprosthesis in the treatment of infra-renal Abdominal Aortic Aneurysms (AAA).
- Trial name
- NCT02308839
- Testing
- GORE® EXCLUDER® Endoprosthesis
- Where
- France
- Volunteers
- 181 people
- Sponsor
- W.L.Gore & Associates
Abdominal Aortic Aneurysms, Thoracoabdominal Aneurysms
Physician-Modified Endografts for Complex Aortic Aneurysms and Thoracoabdominal Aneurysm Repair in High-Risk Patients
This single-arm FDA-monitored protocol intends to broaden endovascular device applicability using physician-modifications in patients who A) Have anatomical conditions not amenable to endovascular repair using currently marketed…
- Conditions
- Abdominal Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aortic Aneurysm
- Trial name
- PMEG (NCT07224230)
- Testing
- Physician Modified Endograft
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Steven Maximus
Abdominal Aortic Aneurysm Patients Under Surveillance
Effects of Beta-blockade on Cardiopulmonary Exercise Testing
A major determinant of perioperative mortality is the inability of the heart to increase its output in response to surgical stress.
- Trial name
- NCT02106286
- Testing
- Bisoprolol
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Michelle Mossa
Abdominal Aortic Aneurysm
Estimation of Biomechanical Aortic Wall Properties in Healthy and Aneurysmal Aortas Using Novel Imaging Techniques
The primary aim of this study is to establish the practicality of using two novel imaging modalities for the assessment of biomechanical properties of the aorta.
- Trial name
- NCT02548546
- Testing
- ECHO, ECG-gated MRA
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm
Physician Modified Endograft For Complex Aortic Aneurysm Repair
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk…
- Conditions
- Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT05339061
- Testing
- Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracoabdominal
Clinical Application of the Medyria TrackCath System in Endovascular Repair of Abdominal Aortic Aneurysms (AAA)
Pre-market, single-arm, prospective, open-label, multi-center clinical trial aimed at assessing the safety and the performance of the Medyria TrackCath system in patients undergoing endovascular intervention.
- Conditions
- Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracoabdominal, Acute Renal Failure, Acute Kidney Injury
- Trial name
- ACCESS (NCT04190979)
- Testing
- Medyria TrackCath System
- Where
- 4 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Medyria AG
Abdominal Aortic Aneurysm Without Rupture
EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study
Prospective, multicenter, single arm study with consecutive, eligible subject enrollment at each site. All subjects will undergo the Endovascular Aneurysm repair procedure with the Nellix System.
- Trial name
- EVAS2 (NCT03298477)
- Testing
- Nellix® System
- Where
- 27 sites in United States
- Volunteers
- 98 people
- Sponsor
- Endologix
Aortic Aneurysm
Modern Technology For Learning and Psychosocial Support In Patients With Abdominal Aortic Aneurysm
This study evaluates the effects of an eHealth tool and psychosocial support on anxiety, depression and health-related quality of life in patients undergoing surgical treatment for abdominal aortic aneurysm (AAA).
- Trial name
- NCT03157973
- Testing
- Education intervention
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska University Hospital
Abdominal Aortic Aneurysm
Limiting AAA With Metformin (LIMIT) Trial
In this research, the investigators are looking at the effects of a drug called metformin may have on the growth of abdominal aortic aneurysm (AAA)s.
- Trial name
- LIMIT (NCT04500756)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Stanford University