Clinical trials: Abdominal Delivery
Cesarean Section, Hypotension
Prevention of Post-spinal Anesthesia Hypotension in Caesarean Delivery Using Delayed Supine Positioning
Maternal hypotension is a common complication after spinal anaesthesia for caesarean delivery. Prophylaxis against post-spinal hypotension (PSH) during caesarean delivery would prevent serious maternal and fetal complications.
- Conditions
- Cesarean Section, Hypotension, Spinal Anaesthesia
- Trial name
- NCT04777123
- Testing
- sitting position
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Shivering, Post-Spinal Shivering
Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section
Spinal anesthesia is the preferred anesthetic method for elective cesarean deliveries, but it frequently causes post-spinal shivering.
- Conditions
- Shivering, Post-Spinal Shivering, Hypothermia, Cesarean Section
- Trial name
- NCT07855523
- Testing
- Midazolam and Ketamine, 0.9% Sodium Chloride
- Volunteers
- 120 people
- Sponsor
- Assiut University
Hypotension
Measuring Cardiac Output and Stroke Volume Using the Physioflow Impedance Device in Pregnant Patients
Pregnant patients having a cesarean section (CS) under spinal anesthesia experience a variety of hemodynamic changes, such as hypotension due to decreases in cardiac output (CO), stroke volume (SV) and/or systemic vascular…
- Trial name
- NCT00573274
- Testing
- Physioflow Impedance
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hypotension
Study to Detect Hypotensive Episodes During Spinal Anesthesia for Cesarean Section Using a Noninvasive Continuous Device
Hypotension after spinal anesthesia for Cesarean section occurs in up to 90% usually under five minutes after local anesthetics administration. These changes are poorly depicted by oscillometric measurements.
- Trial name
- NCT01157520
- Sponsor
- University Hospital Schleswig-Holstein
Cesarean Section Complications
Sublingual Misoprostol and Tranexamic Acid in Pregnant Women With Twin Pregnancy Undergoing Cesarean Section
Purpose to evaluate the effects of sublingual misoprostol with or without intravenous tranexamic acid (TA) in comparison with placebo on reducing post-partum hemorrhage in pregnant women with twin pregnancy undergoing an elective…
- Trial name
- NCT03774524
- Testing
- Misoprostol, TA
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Cesarean Section
MgSO4 as Adjuvants to Bupivacaine vs Neostigmine in TAP Block in Cesarean Section
The aim of this study is to compare the duration of analgesia obtained by addition of Neostigmine versus MgSO4 as adjuvants to bupivacaine in TAP block in patients undergoing Cesarean Section and to evaluate postoperative…
- Trial name
- NCT06513013
- Testing
- transversus abdominis plane (TAP) block in cesarean section, Magnesium sulfate, Neostigmine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Assiut University
Analgesia
Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
The enhanced recovery anesthesia concept has been widely adopted, including cesarean delivery. Modern obstetrical anesthesia aims to offer an experience to a patient undergoing a cesarean delivery similar to normal vaginal…
- Trial name
- NCT05042817
- Testing
- 100 mcg morphine, 0.9% NaCl, 50 mg prilocaine + 2.5 mcg sufentanil
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University of Liege
Operation Wound; Infection, Endometritis
Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section
To evaluate the rate of infections after cesarean sections in patients with premature rupture of membranes after vaginal wash either with an antiseptic solution (clorhexidine solution) vs. saline solution (placebo).
- Trial name
- NCT03442218
- Testing
- Clorhexidine, Saline solution
- Where
- Panama
- Volunteers
- 203 people
- Sponsor
- Saint Thomas Hospital, Panama
Vomiting
Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia
overall incidence of intraoperative nausea and vomiting(IONV) during regional anesthesia for cesarean section is extremely variable, up to 80 percent , depending on the anesthetic technique used (spinal, epidural or combined…
- Trial name
- NCT04785118
- Testing
- Hyoscine N Butylbromide, Ondansetron, Saline
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Assiut University
Cesarean Section
Use of Cesarean Birth at Private Health Facilities in Lilongwe and Blantyre, Malawi
The purpose of the research study is to collect preliminary data to which future outcomes after implementing quality improvement projects or research will be compared.
- Trial name
- NCT04442997
- Where
- 3 sites in Malawi
- Volunteers
- 260 people
- Sponsor
- University of Colorado, Denver
Caesarean Section
Sensitivity of Hyomental Distance Ratio as a Single Predictor of Difficult Intubation in Obstetrics
This is a study to detect the sensitivity of thyromental distance ratio as a single predictor for difficult intubation in patients undergoing cesarean section under general anesthesia.
- Trial name
- HMDR (NCT00916812)
- Where
- United Arab Emirates
- Volunteers
- 188 people
- Sponsor
- King Khaled Eye Specialist Hospital
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor, Analgesia
Postoperative Analgesic Effect of Esketamine
The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section.
- Trial name
- NCT05582135
- Testing
- 2 mg morphine sulfate, 0.25mg/kg esketamine, 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Xuanhan County People's Hospital
Pregnancy
Comparison Between Palpatory and Preprocedural Ultrasound Guided Techniques on Performance of Spinal Anesthesia
Pre-procedural ultrasound for Spinal \& Epidural anesthesia is now being increasingly performed worldwide. Pre-procedural ultrasound assessment of the spine has been shown to facilitate the placement of epidural anesthesia in…
- Trial name
- NCT01865955
- Testing
- Ultrasound, The spinal needle
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hypotension
Corrected Carotid Flow Time for Predicting Spinal Anesthesia-induced Hypotension
Spinal anaesthesia is a standard technique frequently preferred for caesarean section. However, spinal anaesthesia-induced hypotension remains a critical problem causing undesirable maternal symptoms such as nausea, vomiting and…
- Trial name
- NCT06905535
- Volunteers
- 50 people
- Sponsor
- Selcuk University
Labor Induction, Cesarean Delivery
Induction of Labor With Oxytocin: When Should Oxytocin be Held?
The investigators propose to perform a prospective randomized control trial to compare the rate of cesarean delivery in women where Oxytocin (OT) is discontinued once active labor begins (5 cm dilation) when compared with women…
- Trial name
- NCT00957593
- Testing
- Oxytocin, Oxytocin discontinuation
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital
Pregnant Women, Enhanced Recovery After Surgery (ERAS) Protocol
ERAS Protocol on Maternal and Fetal Outcomes Following Elective Cesarean Section
The goal of this observational study is to investigate the maternal, fetal, and neonatal outcomes in parturients scheduled to undergo elective cesarean section (CS) receiving either standard care or enhanced recovery after…
- Trial name
- ERAS (NCT06753058)
- Testing
- 25 gram of maltodextrin in 330 mL , Nutricia Fantomalt 4 Gram, Nutri Gıda Ürünleri San. ve Tic. A.Ş., Istanbul, Türkiye, 2 h prior to surgery., Mother baby bonding
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Gazi University
Postpartum Hemorrhage
Maintenance Infusion of Oxytocin Following Elective Cesarean Deliveries
This study is designed to determine the minimal effective oxytocin maintenance dose required during cesarean delivery to achieve the best effect.
- Trial name
- NCT04946006
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hypotension, Pregnancy
Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients
The investigators hypothesize that given prophylactically, intravenous ondansetron will attenuate the drop in blood pressure and heart rate frequently seen after spinal anesthesia.
- Trial name
- NCT01414777
- Testing
- ondansetron
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Virginia
Pain
Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section
For post-Cesarean analgesia, the investigators will compare the efficacy of single-shot epidural preservative free morphine with a continuous epidural fentanyl infusion.
- Trial name
- NCT01362998
- Testing
- Preservative free morphine, Fentanyl
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Goodman, Evan, M.D.
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