Clinical trials: Abdominal Delivery
Adverse Effect
Preload Optimization Guided by Inferior Vena Cava Collapsibility Index
The purpose of this study is to investigate the optimal preload guided by inferior vena cava collapsibility index in parturients with prophylactic norepinephrine infusion undergoing cesarean section.
- Trial name
- NCT04272580
- Testing
- Control group, 4 ml/kg group., 8 ml/kg group.
- Where
- China
- Volunteers
- 193 people
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Section During Labor
Minimum Oxytocin Dose for Cesarean During Labor: Adaptative Clinical Trial
Introduction: postpartum hemorrage is a leading cause of death after cesarean sections in Brazil. Oxytocin is the main drug for both prophylaxis and threatment of postpartum hemorrage because uterine atony is the most prevalent…
- Trial name
- MODCL (NCT02794779)
- Testing
- Oxytocin
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Brasilia University Hospital
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Spinal, Hypotension
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia in Lower Segment Caesarean Section
Spinal anesthesia for caesarean section is invariably associated with variable degree of hypotension. Hypotension that occurs may be detrimental to various organ system due to inadequate perfusion.
- Conditions
- Spinal, Hypotension, Perfusion Index
- Trial name
- NCT03319433
- Testing
- Perfusion Index
- Volunteers
- 130 people
- Sponsor
- Paropakar Maternity and Women's Hospital
Acute Post-operative Pain Following Caesarean Section
Opioid-free Analgesia for the Management of Acute Post-operative Pain Following Caesarean Section
Background: Multimodal analgesia; a combination of opioid and non-opioid analgesics, for management of acute post-operative pain significantly reduces the incidence of adverse effects associated with liberal post-operative opioid…
- Trial name
- OFAAPPCS (NCT04539249)
- Testing
- Magnesium sulphate, Pentazocine
- Where
- Nigeria
- Volunteers
- 324 people
- Sponsor
- Olakunle Ifeoluwa Makinde
Cicatrix
The Long-term Effect of Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars
The study is to investigate the long-term efficacy of perinatal tissue mesenchyme stem cells treatment on the appearance of a caesarean scar as compared to a similar untreated scar.
- Trial name
- NCT04034615
- Testing
- Mesenchyme Stem Cells low-dose group, Mesenchyme Stem Cells high-dose group
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Hypotension, Nausea
Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section
The purpose of this study is to determine the minimum effective bolus dose of phenylephrine to prevent post-spinal hypotension in Cesarean section in 95 % of our patients.
- Trial name
- NCT00379691
- Testing
- phenylephrine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Surgical Site Infection, Cosmetic Appearance of Cesarean Scar
Prospective Study on Cesarean Wound Outcomes
This study will investigate whether the placement of silver impregnated dressings beginning in the OR will improve wound healing in patients undergoing cesarean delivery compared to traditional Telfa pads.
- Conditions
- Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
- Trial name
- NCT01697748
- Testing
- Silver-impregnated dressing, Telfa pad dressing
- Where
- 3 sites in United States
- Volunteers
- 660 people
- Sponsor
- University of South Florida
Hemorrhage, Cesarean Section
Continuous Non-Invasive Measurement of Hemoglobin During Parturition
A non-invasive hemoglobin monitor will be used during cesarean delivery and the values obtained will be compared to values obtained from traditional blood draw.
- Trial name
- NCT03150043
- Testing
- Masimo Rainbow Pulse CO-oximeter
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cesarean Section, Hypotension
The Effect of Two Different Doses of Noradrenaline on Hypotension Caused by Spinal Anesthesia for Cesarean Section
To compare two infusion rates of norepinephrine for prophylaxis against post-spinal hypotension during caesarean delivery.
- Conditions
- Cesarean Section, Hypotension, Norepinephrine
- Trial name
- NCT06102382
- Testing
- Norepinephrine (0.1), Norepinephrine (0.075)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Obstetrical Complications, Hemorrhage
Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean
A randomized placebo-controlled trial of 11,000 women to assess whether tranexamic acid as prophylaxis lowers the risk of postpartum hemorrhage in women undergoing a cesarean delivery.
- Conditions
- Obstetrical Complications, Hemorrhage, Labor and Delivery
- Trial name
- TXA (NCT03364491)
- Testing
- Tranexamic Acid
- Where
- 12 sites in United States
- Volunteers
- 11,000 people
- Sponsor
- The George Washington University Biostatistics Center
Anesthesia
Comparison of Intratechal Levobupivacaine and Adding With Sufetanil and Fentanyl in Ceserean Section
45 pregnant women undergoing cesarean section were enrolled in the study in november 2006 to march 2007. 2 ml of 0.5% levobupivacaine was added to 1 ml of saline in group I, 1 ml of 15 µcg of fentanyl in group II and 1 ml of 1,5…
- Trial name
- NCT02430090
- Testing
- Levobupivacaine, Fentanyl, Sufentanil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Perinatal Morbidity
Perinatal Morbidity Factors During Cesarean Section
Caesarean section is one of the most common surgeries in the world and the increasing rate of cesarean delivery is associated with increased maternal and fetal morbidity when compared to vaginal delivery.
- Trial name
- NCT03928795
- Testing
- elective caesarean section
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Gestational Diabetes, Gestational Diabetes Mellitus
Gestational Diabetes: Induction Versus Expectant Management of Labour
The purpose of this study is to determine whether, in Gestational Diabetes Mellitus (GDM) pregnancies, induction of labour at 38-39 weeks of pregnancy is superior to expectant management in terms of maternal and neonatal outcomes.
- Conditions
- Gestational Diabetes, Gestational Diabetes Mellitus, Diabetes Mellitus, Gestational, Pregnancy-Induced Diabetes
- Trial name
- GINEXMAL (NCT01058772)
- Testing
- INDUCTION of LABOUR
- Where
- 9 sites in Israel, Italy and 3 more
- Volunteers
- 425 people
- Sponsor
- IRCCS Burlo Garofolo
Labour
Effect of World Health Organization Labour Care Guide On Reducing Cesarean Section Rates
After taking informed consent for participation in the study, all selected cases will be divided into two groups by lottery method.
- Trial name
- NCT07550439
- Testing
- WHO Labour Care Guide, Partogram
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Pak Emirates Military Hospital
Induction Time, Apgar Score
The Balloon Project for Birth Induction
The use of prostaglandin E2 (PGE2) for induction of labour in women with unfavourable cervices is well-established1. There are, however, potential side effects to prostaglandins, in particular the risk of uterine hypertonicity…
- Conditions
- Induction Time, Apgar Score, Admission to Neonatal Unit, Vaginal Delivery
- Trial name
- NCT01255839
- Testing
- Double Balloon, Minprostin
- Where
- Denmark
- Volunteers
- 825 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Adverse Anesthesia Outcome
Phenylephrine and Noradrenaline for Post Spinal Anesthesia Hypotension
Hypotension following spinal anesthesia for cesarean section is a serious problem. In this study we investigated the effect of the vasopressors phenylephrine and noradrenaline on postspinal hypotension.
- Trial name
- NCT03015857
- Testing
- phenylephrine, Norepinephrine, Bupivacaine
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Hypotension
Norepinephrine and Phenylephrine for Maternal Cardiac Output During Spinal Anesthesia for Elective Cesarean Delivery
The purpose of this study is to compare norepinephrine and phenylephrine on the effects of maintaining the cardiac output in Cesarean section under spinal anesthesia.
- Trial name
- NCT02969239
- Testing
- Norepinephrine, Phenylephrine
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Jeju National University Hospital
Caesarean Section, Postoperative Analgesia
Analgesic Effects of Intrathecal Morphine and Transversalis Plane Block After Cesarean Delivery
A comparison of postoperative pain levels, patient satisfaction, and side effects is planned between patients who received morphine during spinal anesthesia for cesarean section and patients who did not receive morphine but…
- Trial name
- NCT07490795
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Vezirköprü State Hospital
Perinatal Depression, Chronic Pain
CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean
The aim is to investigate if inflammatory biomarkers in the blood and cerebrospinal fluid (CSF) are associated with the development of perinatal depression and/or persistent pain after cesarean delivery.
- Trial name
- NCT04271072
- Testing
- No intervention
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Duke University
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