Clinical trials: Abdominal Delivery
Obstetrics: Elective Caesarean Delivery
Effects of Spinal Anesthesia on the Fetal Autonomic Nervous System
Elective cesarean deliveries account for over 10% of births in France and are often scheduled around 39 weeks of gestation. When feasible, spinal anesthesia is considered the gold standard in such a clinical situation.
- Trial name
- RACHISNA (NCT07333729)
- Testing
- Recording of fetal and maternal heart rate
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Hemorrhage, Postpartum
Intrauterine Misoprostol Versus Rectal Misoprostol in Reducing Blood Loss During Cesarean Section
98 pregnant women attending for CS will be randomized into 2 groups. Rectal misopristol group who will receive 400 microgram misoprostol rectally preoperatively with urinary catheter insertion and intrauterine misopristol group…
- Trial name
- NCT03723031
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Continuous Fetal Heart Beat Monitor and Analysis After Spinal Anesthesia
Fetal Heart Rate Pattern After Spinal Anesthesia for Scheduled Uncomplicated Cesarean Section
Spinal anesthesia may cause sympathetic blockade which decrease peripheral vascular resistance and bradycardia and then hypotension.
- Trial name
- NCT05776186
- Testing
- Spinal anesthesia with heavy bupivacaine
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Failed Trial of Labor, Unspecified, With Delivery, Failed VBAC (Vaginal Birth After Caesarean)
Oxytocin Induction in Full Term Pregnant Women With Cesarean Section of Prelabor Rupture of Membranes
This study is a multi-center, prospective, observational clinical trial study. 528 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Failed Trial of Labor, Unspecified, With Delivery, Failed VBAC (Vaginal Birth After Caesarean), Prelabor Rupture of Membranes, Failed Induction (of Labor) by Oxytocin
- Trial name
- NCT05333731
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 528 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Infection
Platelet Rich Plasma and Wound Healing After Cesarean Section
Objective: To assess the effect of autologous Platelet Rich Plasma (PRP) on wound healing and pain perception in high risk women undergoing cesarean sections in a low resource setting.
- Trial name
- NCT04669353
- Testing
- Platelet rich plasma
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Menoufia University
Cesarean Section Complications
The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section
Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine effect on fetus and parturient during Cesarean Section
- Trial name
- NCT03833895
- Testing
- Norepinephrine, Phenylephrine, Ringer's Solution
- Where
- China
- Volunteers
- 238 people
- Sponsor
- China International Neuroscience Institution
Postoperative Pain
Disposition of Intravenous Ketorolac
The purpose of this study is: to document ketorolac disposition (concentration/time profile, protein binding, metabolism) and its covariates following intravenous (iv) administration of ketorolac right after caesarean section and…
- Trial name
- NCT01291472
- Testing
- Ketorolac Tromethamine
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Post Partum Hemorrhage, Cesarean Section Complications
Aortic Compression Trial to Reduce Blood Loss at Cesarean Section
The goal of this clinical trial is to test if manual external aortic compression can prevent heavy blood loss in cesarean section. The main question[s] it aims to answer are: 1. Is external aortic compression effective? 2.
- Conditions
- Post Partum Hemorrhage, Cesarean Section Complications, Anemia
- Trial name
- ACT (NCT05312658)
- Testing
- External aortic compression
- Where
- Sweden
- Volunteers
- 2,246 people
- Sponsor
- Karolinska Institutet
Pain, Postoperative, Cesarean Section Complications
Satisfaction Following Cesarean Section
Presently, the standard of care at the investigators' practice is that the discharging physician decides the type and amount of opioid medication to prescribe a patient following a cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section Complications, Postpartum Disorder, Opioid Use
- Trial name
- NCT03355248
- Testing
- Oxycodone Acetaminophen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ProMedica Health System
Pain, Cesarean Section
Postcesarean Section Pain: Possible Demographic and Medical Predictors
The aim of this retrospective study is to find out if one or more of the following parameters has an impact on postcesarean section pain:age,ethnic origin, parity,body habitus, smoking, breastfeeding, education,newborn in…
- Trial name
- NCT00416104
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Surgical Wound Infection
The Use of a Silver Containing Dressing (Acticoat) on Wound Complication Rates Post Elective Cesarean Section
The purpose of this study is to determine the effect of a silver containing dressing (Acticoat Post-Op) compared to a standard dressing (OpSite PostOp) on post elective cesarean section wound complications in obese women (BMI…
- Trial name
- NCT02288884
- Testing
- Acticoat PostOp, OpSite PostOp
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Postpartum Hemorrhage
Comparative Study Between the Roles of Intrauterine Misoprostol Versus the Sublingual Route for Prevention of Postpartum Blood Loss in Elective Cesarean Sections
Study design: A prospective randomized control trial was carried out at labor and delivery unit at Kasr Al Aini Hospital, Cairo University.
- Trial name
- NCT06364098
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diastasis Recti, Sacroiliac Joint Somatic Dysfunction
Diastasis Recti Abdominis Association With Sacroiliac Joint and Pelvic Floor Dysfunction in Postpartum C-section Women
Purpose: The purpose of the proposed study is to examine the ability of diastasis recti abdominis to predict outcomes of Sacroiliac joint dysfunction and pelvic floor dysfunction.
- Conditions
- Diastasis Recti, Sacroiliac Joint Somatic Dysfunction, Pelvic Floor Disorders
- Trial name
- NCT04519840
- Testing
- nill
- Where
- United Arab Emirates
- Volunteers
- 32 people
- Sponsor
- Dubai Health Authority
Cesarean Section Complications
Impact of a Strategy Combining Morphine Savings and Anesthesia Technique on the Quality of Post-operative Rehabilitation
The aim of REHACESAR is to study the impact of an association of a low dose of neuraxial morphine and a locoregional anesthesia (TAP block or catheter for continuous wound infiltration) on quality of recovery after cesarean…
- Trial name
- REHACESAR (NCT04377984)
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Postoperative Pain
Dexmedetomidine Wound Infiltration in Cesarean Section
The effects of four different wound infiltration protocols in cesarean section will be investigated on parturient' pain intensity, PCA morphine consumption given, side effects and parturient' overall satisfaction.
- Trial name
- NCT03382938
- Testing
- Dexmedetomidine, Ropivacaine, Dexmedetomidine - Ropivacaine
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Uterine Rupture Gravid
Uterine Rupture International Data Acquisition
Uterine rupture represents an uncommon event: it is is a life-threatening obstetric complication with high maternal and perinatal morbidity and mortality.
- Trial name
- URIDA (NCT03576950)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Post Partum Hemorrhage
Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
The goal of this study is to compare 2 medications that are commonly used to prevent excess uterine bleeding (postpartum hemorrhage, or PPH) following cesarean delivery (CD), oxytocin and carbetocin.
- Trial name
- NCT06333340
- Testing
- Oxytocin, Carbetocin
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy, Respiratory Aspiration of Gastric Content
Intra- and Interrater Reliability of Quantitative Ultrasound Assessment of Gastric Content in Term Parturients Before Elective Caesarean Delivery
The presence of solid food or fluid residue in the stomach is always a major concern when patients require medical procedures under sedation or general anesthesia, due to the high risk of pulmonary aspiration of the stomach…
- Trial name
- NCT05946447
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Drying Time
Chlorhexidine Drying Time
Before a patient gets a spinal/epidural, their lower back is cleaned with an antiseptic solution diluted in alcohol called ChloraPrep. ChloraPrep must completely dry before starting the anesthetic procedure.
- Trial name
- Chlorhexidine (NCT02095535)
- Testing
- Chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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