Clinical trials: Abdominal Delivery
Cesarean Section, Wound Complications
Cesarean Trial of Staples vs. Sutures
To determine whether the rate of wound complications differs based on method of closure of skin incision (staples vs. suture) after cesarean delivery.
- Conditions
- Cesarean Section, Wound Complications, Patient Satisfaction, Pain Measurement
- Trial name
- CROSS (NCT01211600)
- Testing
- Staples, Suture
- Where
- 2 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib
Cesarean Delivery
Prevention of Intraoperative Nausea and Vomiting During Cesarean Section
The study investigates the incidence of intraoperative nausea and vomiting under spinal anesthesia using a phenylephrine infusion with and without prophylactic antiemetics.
- Trial name
- NCT01216410
- Testing
- Metoclopramide, Phenylephrine infusion, Combination Group
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- Duke University
Postpartum Hemorrhage
Tranexamic Acid and Thromboelastography During Cesarean Delivery
The aim of this study is to characterize the coagulation changes, using thromboelastography (TEG), after prophylactic tranexamic administration during cesarean delivery.
- Trial name
- TA TEG (NCT02026297)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brigham and Women's Hospital
Cesarean Section, Complication
A Skin Glue Versus Subcuticular Suture for Cesarean Closure Study
The aim of this study is to compare cesarean incision outcomes between patients with incision closed with the Dermabond Prineo system compared to standard subcuticular suture.
- Conditions
- Cesarean Section, Complication, Wound
- Trial name
- NCT05903547
- Testing
- Dermabond Prineo, Suture
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Columbia University
Anesthesia, Spinal, Cesarean Section
Ultrasonography Versus Palpation for Spinal Anesthesia in Obese Parturients Undergoing Cesarean Delivery
The study will compare between preprocedural ultrasonography and the conventional palpation technique for spinal anesthesia in obese parturients undergoing elective cesarean delivery
- Conditions
- Anesthesia, Spinal, Cesarean Section, Spinal Ultrasound
- Trial name
- NCT03792191
- Testing
- Lumbar Spinal Ultrasonography, Conventional Landmark Palpation, Spinal Anesthesia
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Mansoura University
Nausea, Vomiting
Acupuncture Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean
The purpose of this study is to compare the effectiveness of acupressure point P6 stimulation versus intravenous ondansetron plus metoclopramide versus no antiemetic prophylaxis during elective cesarean section under regional…
- Conditions
- Nausea, Vomiting, Satisfaction
- Trial name
- NCT02959840
- Testing
- Acupressure Point P6 stimulator, Metoclopramide, Ondansetron
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Enterocolitis, Necrotizing, Premature Infant
NEC Screening Abdominal Radiograph vs Bowel Ultrasound in Preemies
The overall primary objective is to establish the feasibility and pilot the design and delivery of a diagnostic randomized controlled trial (RCT) of BUS (bowel ultrasound) for NEC evaluation which will lead to a successful…
- Trial name
- NCT03963011
- Testing
- Bowel Ultrasound
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Children's Mercy Hospital Kansas City
Postoperative Pain
A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients
This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively.
- Trial name
- NCT02619799
- Testing
- intrathecal magnesium sulphate,, Intrathecal midazolam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rangaraya Medical College
Any Solid Malignancies of Any Tissue Origin (Except for Small Cell Lung Cancer) Involving the Upper Abdomen and Thorax
Novel Optical Surface Image Guidance System for Beam-Gated Online Adaptive SBRT Delivery in Mobile Lower Lung and Upper Abdominal Malignancies
Motion during radiation therapy can be categorized as inter-fraction (changes in anatomy that occur between treatment days) and intra-fraction (changes that occur during the "beam on" window of treatment delivery).
- Trial name
- NCT05030454
- Testing
- ETHOS, CT-guided stereotactic adaptive radiotherapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Cesarean Section Complications, Post Partum Hemorrhage
DAISY Uterine Drain Device Evaluation
The goal of this study is to obtain user feedback while placing and observing the DAISY uterine drain with wall suction. This study defines the obstetrical surgeons as "users" and the patients in whom the drain is placed as…
- Conditions
- Cesarean Section Complications, Post Partum Hemorrhage, Uterine Atony With Hemorrhage, Uterine Bleeding
- Trial name
- NCT06219538
- Testing
- DAISY Uterine Drain
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Raydiant Oximetry, Inc.
Labor Pain, Complications; Cesarean Section
Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
To compare the effects of epidural versus combined spinal and epidural (CSE) anesthesia on the success of Trial of Labor After Cesarean (TOLAC).
- Conditions
- Labor Pain, Complications; Cesarean Section, Pregnancy
- Trial name
- NCT02105558
- Testing
- Epidural anesthesia, Combined spinal and epidural anesthesia
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity, Morbid, Spinal Anesthesia
ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
The aim of this study is to determine the ED90 of hyperbaric intrathecal bupivacaine for the super obese population undergoing cesarean section under a combined spinal epidural technique.
- Conditions
- Obesity, Morbid, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT03781388
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Duke University
C-Section, Pain Management
Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
Primary objective: The primary objective of this study is to compare total opioid consumption through 72 hours following EXPAREL+bupivacaine HCl infiltration into the transversus abdominis plane (TAP) after spinal anesthesia to…
- Trial name
- C-Section (NCT03176459)
- Testing
- Exparel + Bupivacaine, Bupivacaine
- Where
- 12 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Complications After Cesarean Section
Enemas Before Elective Cesarean Section
Enemas are not anymore used routinely before vaginal deliveries.The intention of this study is to elucidate whether there is a benefit in routine use of enema before cesarean section.
- Trial name
- NCT00391599
- Testing
- enema
- Volunteers
- 130 people
- Sponsor
- Wolfson Medical Center
Surgery, Opioid Use
Opioid Prescribing After Cesarean Delivery
The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic.
- Trial name
- NCT03168425
- Testing
- Tailored prescription, Control
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pain
Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
The purpose of this study is to determine if the infusion of the local anesthetic ropivacaine (a numbing medicine) and the non-steroidal anti-inflammatory drug ketorolac (a pain killer similar to ibuprofen) through a catheter…
- Trial name
- NCT02829944
- Testing
- Ropivacaine, Ketorolac
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Duke University
Placenta Accreta, Postpartum Hemorrhage
Perioperative Administration of Tranexamic Acid for Placenta Previa and Accreta Study
The purpose of this pilot study is to determine if intravenous tranexamic acid (TXA) is effective for reducing blood loss during high risk surgical procedures related to placenta previa and placenta accreta.
- Conditions
- Placenta Accreta, Postpartum Hemorrhage, Cesarean Section, Tranexamic Acid
- Trial name
- TAPPAS (NCT02806024)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Pain
Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section
This is a Phase 4, multicenter, open-label study evaluating EXPAREL infiltration into the transversus abdominis plane (TAP) after bupivacaine hydrochloride (HCl) spinal anesthesia in subjects undergoing elective Cesarean section…
- Trial name
- NCT02353754
- Testing
- Intrathecal morphine injection, EXPAREL
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Endometritis
Reduction of Endometritis After Cesarean Section With the Routine Use of Methergine
Endomyometritis is an "infection in the uterus". It can occur in up to 1 out of 5 women having unplanned cesarean deliveries. Antibiotics are routinely given at the time of Cesarean delivery, but the infection in the uterus can…
- Trial name
- NCT00858832
- Testing
- Methergine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of South Florida