Clinical trials: Abdominal Delivery
Microbial Colonization, Antibiotic Side Effect
Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome.
- Conditions
- Microbial Colonization, Antibiotic Side Effect, Cesarean Section Complications
- Trial name
- CSBabyBiome (NCT06030713)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Cesarean
Prilocaine or Bupivacaine for Spinal Anesthesiain Pregnant
The planned cesarean section is an intervention with a standard operating time of less than 40 minutes in trained teams. Hyperbaric Bupivacaine is the local anesthetic (LA) reference for these operations.
- Trial name
- Césarcaïne (NCT03433976)
- Testing
- spinal anesthesia
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Postoperative Pain
Efficacy of Intrathecal Clonidine Versus Neostigmine as Adjuvants to Bupivacaine on Postoperative Maternal and Fetal Outcomes After Elective Cesarean Section
The delivery of the infant into the arms of a conscious and pain free mother is one of the most exciting and rewarding moments in medicine.
- Trial name
- NCT05943613
- Testing
- Clonidine
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section
Use of Cesarean Birth at Private Health Facilities in Lilongwe and Blantyre, Malawi
The purpose of the research study is to collect preliminary data to which future outcomes after implementing quality improvement projects or research will be compared.
- Trial name
- NCT04442997
- Where
- 3 sites in Malawi
- Volunteers
- 260 people
- Sponsor
- University of Colorado, Denver
Hypotension
ET 50 for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50 (NCT01561274)
- Testing
- 2 ml bupivacaine, 1.5 ml bupivicaine.
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain, Postoperative, Opioid Use
Liposomal Bupivacaine After Cesarean Delivery
The aim of this study is to determine if local wound infiltration with liposomal bupivacaine at the time of cesarean delivery can decrease opioid use and provide adequate post-operative pain control.
- Trial name
- NCT03907813
- Testing
- Exparel, Saline infiltration
- Where
- United States
- Sponsor
- Wright State University
Obstetric Labor Complications
Dynamic Ultrasound for Prediction of Adhesion Section
1. To validate the use of dynamic ultrasound for prediction of adhesions in women undergoing repeated cesarean section. 2. To detect the interobserver and intraobserver reliability of this method
- Trial name
- NCT03862820
- Testing
- dynamic ultrasound
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Delivery Affecting Fetus or Newborn, Labor (Obstetrics)--Complications
Two Previous Cesarean and Vaginal Birth Before and After Starting Training and Protocols
In 2015 ObGyn Dept of Santo Spirito Hospital in Pescara (Italy) started protocol for previous CS vaginal birth. In 2021 was started a protocol for training on obstetric emergencies and protocol on two previous cesarean was…
- Conditions
- Cesarean Delivery Affecting Fetus or Newborn, Labor (Obstetrics)--Complications, Hemorrhagic Complications
- Trial name
- TOLA2C Train (NCT07258459)
- Testing
- Acceptance, rate of vaginal birth and safety
- Where
- 2 sites in Italy
- Volunteers
- 2,016 people
- Sponsor
- G. d'Annunzio University
Hypotension
Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean Section
Hypotension occurs commonly during spinal anesthesia for caesarean section with maternal and fetal adverse effects. The investigators developed a double-vasopressor automated system incorporating continuous non-invasive arterial…
- Trial name
- NCT04025918
- Testing
- Vasopressor automated delivery system, Phenylephrine, Ephedrine
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Post Partum Hemorrhage
A Comparative Study Between Bakri Balloon and B Lynch Suture Used to Control Primary Postpartum Hemorrhage After Cesarean Section
Hundred (100) patients with primary postpartum hemorrhage during caesarean section due to atonic uterus will be recruited for this study.and randomized to either B lynch or Bakeri Ballon B-Lynch: A 70 mm round bodied hand needle…
- Trial name
- NCT03891082
- Testing
- B-Lynch, BALLOON INSERTION
- Volunteers
- 100 people
- Sponsor
- Cairo University
Cesarean Section Complications
Knot Burial Technique for Rectus Sheath Closure
Caesarean section is one of the most commonly performed abdominal operations on women in most countries of the world. Its rate has increased markedly in recent years, and is about 20-25% of all child-births in most developed…
- Trial name
- NCT04156282
- Testing
- knot burial technique, classical closure
- Where
- Egypt
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Placenta Accreta Spectrum
Risk Factors, Prognosis and Prediction Models for Placenta Accreta Without Prior Cesarean Section
1. Identify the risk factors for Placenta accreta spectrum (PAS) disorders in women without prior caesarean section (CS). 2. Clarify the prognostic factors of the disease and explore individualized treatment options to improve…
- Trial name
- NCT06383923
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Cesarean Wound; Dehiscence, Cesarean Section Complications
Lower Uterine Segment Following a Cesarean Section With Barbed Suture
This aim of this study is to investigate the LUS in the pregnancy following a previous cesarean section with the use of barbed or conventional smooth suture.
- Trial name
- BARB-LOWSEGM (NCT05166174)
- Testing
- Transvaginal ultrasound in the third trimester pregnancy
- Where
- Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Cesarean Section Complications
Impedance Cardiography as Tool for Continuous Hemodynamic Monitoring During Cesarean Section
Impedance Cardiography (ICG) is a non-invasive tool for continuous hemodynamic monitoring. Aims of our study is to assess the utility of ICG to evaluate the hemodynamic impact of 6 mg (GL6) vs 8 mg (GL8) levobupivacaine combined…
- Trial name
- NCT03170427
- Testing
- Impedance cardiography, Sensory levels, Motor block
- Volunteers
- 62 people
- Sponsor
- University of Foggia
Cesarean Section Rates
Cesarean Delivery in Uganda: A Mixed Methods Study
Recent data indicate that 1 in 5 women worldwide undergo Caesarean sections (CS) and in most regions CS rates are increasing. Sub-Saharan Africa has the lowest CS rate at 3.5%, compared to a global average of 19.1%.
- Trial name
- CRADLING (NCT06090695)
- Where
- 14 sites in Uganda
- Volunteers
- 11,760 people
- Sponsor
- Massachusetts General Hospital
Post Partum Hemorrhage
Prevention of Postpartum Haemorrhage
Use of Tranexamic Acid for prevention of Postpartum hemorrhage in high risk patients: Randomized Control Trial
- Trial name
- NCT04463966
- Testing
- Tranexamic acid injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Wound Infection
Swabbing of Subcutaneous Tissues of Cesarean Section Wounds With Povidone Iodine
The study has 2 groups. Group A in which the subcutaneous tissue will be swabbed with 10 cc of undiluted 10% povidone iodine and will not be mobbed. Group B ; No swabbing.
- Trial name
- NCT02868372
- Testing
- Povidone iodine
- Volunteers
- 538 people
- Sponsor
- Assiut University
Cesarean Section, Dysmenorrhea
Association Between Cesarean Scar Mobility and Menstrual Pain in Post-Cesarean Women
The aim of this observational cross-sectional study is to investigate the association between cesarean scar mobility and menstrual pain severity in women following cesarean section.
- Trial name
- NCT07729254
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Cairo University
Adverse Effect
ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients
The objective of this study is to investigate the ED90 of norepinephrine and phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive treatment in preeclamptic patients during cesarean section
- Trial name
- NCT06158022
- Testing
- Norepinephrine, Phenylephrine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- General Hospital of Ningxia Medical University
Postpartum Women
The Effects of Acupressure on Pain After Cesarean Section
Purpose: To examine the effect of Pericardium 6 and Large Intestine 4 acupressure on pain and analgesia consumption in women after cesarean section.
- Trial name
- NCT04337801
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
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