Clinical trials: Abdominal Delivery
Surgical Site Infection
Betadine Versus Saline in Swapping of Subcutaneous Tissue
Caesarean section is an increasingly common major surgical procedure performed on women. Last decade an overall increase of the global rate of caesarean section, of up to 31.2%, was reported.
- Trial name
- NCT06595823
- Testing
- Betadine
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Egymedicalpedia
Post-operative Nausea and Vomiting
Effect of Using Azithromycin Versus Placebo With Dexamethasone in Prevention of Post-spinal Nausea and Vomiting.
Postoperative nausea and vomiting is defined as any nausea, retching, or vomiting occurring during the first 24-48 h after surgery in inpatients.
- Trial name
- NCT03165123
- Testing
- Oral Azithromycin tablet, Intravenous dexamethasone
- Volunteers
- 160 people
- Sponsor
- Assiut University
Obstetric Anesthesia Problems, Placenta Accreta
Fibrinogen Concentrate and Placenta Acreta Spectrum
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
- Trial name
- NCT05938062
- Testing
- the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Thinned-out Lower Uterine Segment Scar Previous Cesarean Section
Comparison of Purse String Suture vs Transverse Mattress Suture to Maintain Hemostasis in Thinned-out Caesarean Sections Scars
Brief Summary The goal of this clinical trial is to compare the effectiveness of purse-string suture versus transverse mattress suture for achieving hemostasis in women with thinned-out lower uterine segment scars undergoing…
- Trial name
- NCT07758959
- Testing
- Purse-String Suture, Transverse Mattress Suture
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Natasha Bushra
Cesarean Section Complications
Buccal Misoprostol and Intravenous Tranexamic Acid During Emergent Cesarean Delivery
Purpose to evaluate the effects of buccal misoprostol with or without intravenous tranexamic acid (TA) in comparison with placebo on reducing post-partum hemorrhage in pregnant women undergoing emergent cesarean section
- Trial name
- NCT03777696
- Testing
- Misoprostol, TA
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- hany farouk
Delivery, Obstetric
The Effect of Warmed Parenteral Fluids During Delivery
To evaluate the influence of warm IV fluids during delivery and cesarean section on perinatal outcomes.
- Trial name
- NCT03178461
- Testing
- Body temperature parenteral fluids
- Where
- 2 sites in Israel
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Intrauterine Devices, Cesarean Section
Immediate Postplacental Insertion of IUDs at Time of Cesarean Delivery: A Randomized Clinical Trial
This is a randomized controlled trial among women who deliver by cesarean at UNC Women's Hospital and desire an Intrauterine Device (IUD) for contraception postpartum.
- Trial name
- IUD@CSD (NCT01539759)
- Testing
- Immediate Postplacental Placement of an IUD during cesarean delivery
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of North Carolina, Chapel Hill
Maternal Anxiety, Cesarean Delivery
Restrained vs Gripping String Techniques in Patients Undergoing Cesarean Delivery
This randomized controlled trial will compare two upper-extremity restraint techniques in patients undergoing elective cesarean delivery under neuraxial anesthesia.
- Trial name
- NCT07772219
- Testing
- Standard Forearm Restraint, Wrist-Level Gripping Restraint
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- Ohio State University
Atelectasis, Cesarean Section
The Effect of Oxygen Therapy on Atelectasis
In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis.
- Conditions
- Atelectasis, Cesarean Section, Hypotension
- Trial name
- NCT05509764
- Testing
- lung ultrasound score
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Cesarean Section; Infection, Surgical Site Infection
Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline
The purpose of this study is to see whether chlorhexidine is superior to povidine-iodine vaginal antisepsis at reducing bacteria colony counts in pregnant women by comparing three groups: vaginal washing with…
- Trial name
- NCT03640507
- Testing
- Chlorhexidine-alcohol, Povidine-iodine, Sterile saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Columbia University
Postoperative Analgesia After Cesarean Delivery
Ultrasound-Guided Posterior Quadratus Lumborum Block With Bupivacaine and Dexmedetomidine Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Cesarean delivery (CD) is one of the most commonly performed surgical procedures worldwide, with millions of women undergoing the procedure annually (1).
- Trial name
- NCT07807592
- Testing
- Intrathecal Morphine, Ultrasound-Guided Posterior Quadratus Lumborum Block
- Volunteers
- 80 people
- Sponsor
- Assiut University
Dexmedetomidine
Comparing Doses of Intrathecal Dexmedetomidine
To compare the duration of sensory and motor blockade produced by two different intrathecal doses of dexmedetomidine (5 µg and 10 µg) when added to hyperbaric bupivacaine in patients undergoing elective cesarean section
- Trial name
- NCT07395271
- Testing
- Dexmedetomidine 5 mcg, Dexmedetomidine 10 mcg
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Bahria International Hospital
Contraception
IUD Insertion During Cesarean Section
Insertion of Intrauterine Contraceptive Device during Cesarean Section: Randomized Clinical Trial
- Trial name
- NCT03492034
- Testing
- IUD during CS, IUD after puerperium
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Hyperalgesia, Secondary
Transversus Abdominis Plane (TAP) Block for Cesarean Section
The purpose of this study is to determine whether a transversus abdominis plane (TAP) block with Clonidine added to the injectate (Clo-TAP) performed approximately 2hrs after the cesarean section (CS) will decrease the amount of…
- Trial name
- CLOTAP (NCT01015807)
- Testing
- Bupivacaine, Clonidine
- Where
- 2 sites in United States, Brazil
- Volunteers
- 90 people
- Sponsor
- University of Washington
Regional Block
Quadratus Lumborum Block Type 2 Versus Posterior Transversus Abdominus Plane Block
This patient population are at risk of adverse effects secondary to inadequate pain management such as inadequate maternal bonding and late ambulation.
- Trial name
- quadratus (NCT04773730)
- Testing
- Posterior transversus abdominus plane block, Quadratus lumborum block type 2
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Cesarean Section Complications
Tranexamic Acid for the Control of Blood Loss at Elective Cesarean Section
The aim of the study is to determine, out of two doses (a standard and a low dose) compared to placebo, the optimal and minimal dose of an intravenously administered single bolus of tranexamic acid(TA) to reduce blood loss when…
- Trial name
- NCT03710330
- Testing
- normal saline, 1gm tranexamic acid, 0.5 gm tranexamic acid
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Aswan University Hospital
Postpartum Hemorrhage, Cesarean Section Complications
The Impact of Mechanical Methods on the Postpartum Haemorrhage Prophylaxis During Caesarean Section
The rate of heavy blood loss is higher in Cesarean delivery compared to vaginal deliveries. Since postpartum hemorrhage is a life threatening situation to decrease the maternal mortality and morbidity rates, precautions should be…
- Trial name
- NCT05948436
- Testing
- Clamping the uterine artery bilaterally during Cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain
Factors Predicting Postoperative Cesarean Section Pain
In spite of identical analgesic protocols, parturients suffer different levels of pain postoperative lay. In this study we hope to identify factors which influence the perception of pain including preoperative anxiety, sleep…
- Trial name
- NCT02033304
- Where
- 2 sites in Israel
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Postoperative Pain, Cesarean Section Pain
Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section
This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section.
- Trial name
- KETODEX-CS (NCT07022821)
- Testing
- Dexmedetomidine, ketamine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Memorial Hospital
Scar Niche, Myometrial Remodeling
Postplacental Copper Intrauterine Device Versus Postpartum Progesterone-only Pills on Uterine Niche Formation
The purpose of the study is to determine whether immediate postplacental copper T380A intrauterine device insertion increases uterine-niche incidence compared with postpartum progestin-only pills after primary cesarean section .
- Conditions
- Scar Niche, Myometrial Remodeling, Contraceptive Device; Complications, Cesarean Section Complications
- Trial name
- T380A (NCT07264933)
- Testing
- Primary Cesarean Section, immediate postplacental insertion of a copper T380A intrauterine device, progesterone-only pills
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Benha University
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